Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Andria Doty"'
Autor:
Phillip M. Mackie, Adithya Gopinath, Dominic M. Montas, Alyssa Nielsen, Aidan Smith, Rachel A. Nolan, Kaitlyn Runner, Stephanie M. Matt, John McNamee, Joshua E. Riklan, Kengo Adachi, Andria Doty, Adolfo Ramirez-Zamora, Long Yan, Peter J. Gaskill, Wolfgang J. Streit, Michael S. Okun, Habibeh Khoshbouei
Publikováno v:
JCI Insight, Vol 7, Iss 4 (2022)
Monocyte-derived macrophages (MDMs) are key players in tissue homeostasis and diseases regulated by a variety of signaling molecules. Recent literature has highlighted the ability for biogenic amines to regulate macrophage functions, but the mechanis
Externí odkaz:
https://doaj.org/article/263453e666ba4697b86326efb160a36d
Autor:
Changlin Yang, Guimei Tian, Mariana Dajac, Andria Doty, Shu Wang, Ji-Hyun Lee, Maryam Rahman, Jianping Huang, Brent A. Reynolds, Matthew R. Sarkisian, Duane Mitchell, Loic P. Deleyrolle
Publikováno v:
Cancers, Vol 14, Iss 5, p 1126 (2022)
Glioblastoma (GBM) exhibits populations of cells that drive tumorigenesis, treatment resistance, and disease progression. Cells with such properties have been described to express specific surface and intracellular markers or exhibit specific functio
Externí odkaz:
https://doaj.org/article/76f70c18b5a44ac4afe5e1858ff59821
Autor:
Paul R. Dominguez-Gutierrez, Elizabeth P. Kwenda, William Donelan, Mariza Miranda, Andria Doty, Padraic O’Malley, Paul L. Crispen, Sergei Kusmartsev
Publikováno v:
The Journal of Immunology. 208:2829-2836
Expression of the transmembrane protein PD-L1 is frequently upregulated in cancer. Because PD-L1–expressing cells can induce apoptosis or anergy of T lymphocytes through binding to the PD1 receptor, the PD-L1–mediated inhibition of activated PD1+
Autor:
Hector Mendez-Gomez, Anna DeVries, Brian Stover, Dingpeng Zhang, Adam Grippin, Christina Von Roemeling, Frances Weidert, Aida Karachi, Sadeem Qdaisat, Nagheme Thomas, James McGuiness, Paul Castillo, Jianping Huang, John Ligon, Natalie Silver, Patrick Kellish, Andria Doty, Sheila Carrera-Justiz, Michael Prados, Sabine Mueller, Maryam Rahman, Ashley Ghiaseddin, Duane Mitchell, Elias Sayour
Publikováno v:
Neuro-Oncology. 24:vii66-vii67
BACKGROUND Although mRNA vaccines have been deployed with great success against COVID-19, unlocking this technology against glioblastoma will necessitate new lipid-nanoparticle formulations that overcome cancer tolerance and immunosuppression. OBJECT
Autor:
CHRISTINA M. GOBIN, JAMES N. MENEFEE, CHAYIL C. LATTIMORE, ANDRIA DOTY, KRISTIANNA M. FREDENBURG
Publikováno v:
Anticancer research. 42(6)
miRNA functional analysis involves transfection with miRNA-based oligos to identify gain-of or loss-of function cellular phenotypes. Apoptosis is a common phenotypic endpoint for miRNA functional analysis. We report that four common cell dissociation
Publikováno v:
The Journal of Immunology. 198:208.14-208.14
The IL10 knockout (KO) mouse is a model for environmentally and genetically triggered spontaneous colitis. The response of the adaptive immune system to these changes has been studied extensively in this model. However, the response of the innate imm
Publikováno v:
The Journal of Immunology. 198:55.45-55.45
Introduction Crohn’s disease (CD) is one form of inflammatory bowel disease (IBD). Traditionally, adaptive immunity has been presumed to play a major role in the pathogenesis of CD. Recently, increasing evidence indicates that innate immunity also
Publikováno v:
The Journal of Immunology. 196:129.11-129.11
The aryl hydrocarbon receptor (AHR) is a ligand-dependent transcription factor. Initial studies of AHR concentrated on its role in the detoxification of xenobiotics. However, recent research has focused on its role in the immune system. AHR has been
Autor:
Andria Doty, Margo L. Macpherson, Margolotza Pozor, Mats H.T. Troedsson, William C. Buhi, Charlotte Dow, S. Benson
Publikováno v:
Biology of Reproduction. 77:128-128