Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Andri Vasou"'
Publikováno v:
Viruses, Vol 9, Iss 7, p 186 (2017)
Modern vaccinology has increasingly focused on non-living vaccines, which are more stable than live-attenuated vaccines but often show limited immunogenicity. Immunostimulatory substances, known as adjuvants, are traditionally used to increase the ma
Externí odkaz:
https://doaj.org/article/f3bf6b1140834877aa05cafcb30fd647
Autor:
Richard E. Randall, John McLauchlan, David J. Hughes, Katie Nightingale, Andri Vasou, Connor G. G. Bamford, Michael P. Weekes, J. Andrejeva, Cetkovská
Type I interferon (IFN) signalling induces the expression of several hundred IFN-stimulated genes that provide an unfavourable environment for viral replication. To prevent an overexuberant response and autoinflammatory disease, IFN signalling requir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::900308aa2b8562923a86ca08d6c11921
https://doi.org/10.1101/2021.06.01.446527
https://doi.org/10.1101/2021.06.01.446527
Autor:
Andri Vasou, David J. Hughes, Elizabeth B. Wignall-Fleming, Steve Goodbourn, Richard E. Randall, Jessie Short, Dan Young
Publikováno v:
Journal of Virology
Copyback defective virus genomes (DVGs) are powerful inducers of innate immune responses both in vitro and in vivo. They impact the outcome of natural infections, may help drive virus‐host coevolution, and promote virus persistence. Due to their po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::763921192e68ba5bab1ebb7a332bb792
https://pubmed.ncbi.nlm.nih.gov/32295916
https://pubmed.ncbi.nlm.nih.gov/32295916
Autor:
J. Andrejeva, Andri Vasou, David J. Hughes, John McLauchlan, Connor G. G. Bamford, David Holthaus, Christina Paulus, Richard E. Randall
Publikováno v:
The Journal of Immunology Author Choice
Key Points Cell culture model of ISG15 deficiency replicates findings in ISG15−/− patient cells. Cause of resistance in ISG15−/− cells differs depending on duration of IFN treatment. ISG15−/− patients without serious viral disease do not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76b0841136ce0776f21fed33da46d01f
https://doi.org/10.1101/2019.12.12.873919
https://doi.org/10.1101/2019.12.12.873919
Autor:
David Holthaus, John McLauchlan, David J. Hughes, J. Andrejeva, Andri Vasou, Richard E. Randall, Connor G. G. Bamford
Publikováno v:
Access Microbiology. 1
Viral infections induce profound cellular responses resulting the expression of hundreds of IFN-stimulated genes (ISGs). Some ISGs have specific antiviral activity, while others regulate the cellular response. For most viruses, the specific antiviral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de415f5cb49588361fb9e1f8f3a6f82d
https://doi.org/10.1099/acmi.ac2019.po0093
https://doi.org/10.1099/acmi.ac2019.po0093
Publikováno v:
Journal of Biomolecular Screening
Production of type I interferon (IFN) is an essential component of the innate immune response against invading pathogens. However, its production must be tightly regulated to avoid harmful effects. Compounds that modulate the IFN response are potenti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::beebaf99d4a49699884089188f601323
https://pubmed.ncbi.nlm.nih.gov/27358388
https://pubmed.ncbi.nlm.nih.gov/27358388
Autor:
Andri Vasou, Katie Nightingale, Vladimira Cetkovska, Connor Bamford, Jelena Andrejeva, Richard Randall, John McLauchlan, Michael Weekes, David Hughes
Publikováno v:
University of St Andrews CRIS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::5be931ab14ae0ea6c0daeccebc162c92
https://risweb.st-andrews.ac.uk/portal/en/researchoutput/a-coopted-isg15usp18-binding-mechanism-normally-reserved-for-deisgylation-controls-type-i-ifn-signalling(ed8a6d83-bfac-4f1e-a40f-42518fd1e675).html
https://risweb.st-andrews.ac.uk/portal/en/researchoutput/a-coopted-isg15usp18-binding-mechanism-normally-reserved-for-deisgylation-controls-type-i-ifn-signalling(ed8a6d83-bfac-4f1e-a40f-42518fd1e675).html