Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Andrey V. Malkovskiy"'
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract CLARITY is a tissue preservation and optical clearing technique whereby a hydrogel is formed directly within the architectural confines of ex vivo brain tissue. In this work, the extent of polymer gel formation and crosslinking within tissue
Externí odkaz:
https://doaj.org/article/1a4ac66481044f91b5e655f93b6111f9
Autor:
Nir Qvit, Deborah Schechtman, Darlene Aparecida Pena, Denise Aparecida Berti, Chrislaine Oliveira Soares, Qianqian Miao, Liying (Annie) Liang, Lauren A. Baron, Christian Teh-Poot, Pedro Martínez-Vega, Maria Jesus Ramirez-Sierra, Eric Churchill, Anna D. Cunningham, Andrey V. Malkovskiy, Nancy A. Federspiel, Fabio Cesar Gozzo, Ana Claudia Torrecilhas, Maria Julia Manso Alves, Armando Jardim, Ndao Momar, Eric Dumonteil, Daria Mochly-Rosen
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 6, Iss 1, Pp 74-84 (2016)
Parasitic diseases cause ∼500,000 deaths annually and remain a major challenge for therapeutic development. Using a rational design based approach, we developed peptide inhibitors with anti-parasitic activity that were derived from the sequences of
Externí odkaz:
https://doaj.org/article/4cd893de292342dcb247cf36ee86cb22
Autor:
Kyung Oh Jung, Jung Ho Yu, Craig S. Levin, Andrey V Malkovskiy, Edwin Chang, Jarrett Rosenberg, Aimen Zlitni, Seung-min Park, Hadas Frostig, Guillem Pratx, Sanjiv S. Gambhir, Idan Steinberg, Jos L. Campbell, Luis Dan Curet, Rochelle Karina Radzyminski, Aloma L. D'Souza, Ryan M. Davis, Daniel Tan Chung
Publikováno v:
ACS Nano
In vivo multiplexed imaging aims for noninvasive monitoring of tumors with multiple channels without excision of the tissue. While most of the preclinical imaging has provided a number of multiplexing channels up to three, Raman imaging with surface-
Autor:
Jayakumar Rajadas, Yuanyuan Dai, Nadezda Ignatyeva, Gerd Hasenfuss, Andrey V Malkovskiy, Antje D. Ebert
Publikováno v:
Biological Chemistry. 402:113-121
We developed a new approach for combined analysis of calcium (Ca2+) handling and beating forces in contractile cardiomyocytes. We employed human induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) from dilated cardiomyopathy (DCM) patient
Autor:
Luis C. Romero, Ai My Luong, Jenny C Mortimer, Nicolas L. Taylor, Sergio Alan Cervantes-Pérez, David W. Ehrhardt, Yana Kazachkova, Adrien Burlaocot, Rajiv K. Tripathi, Alfredo Cruz-Ramírez, Nicholas J. Provart, Uwe John, Shou-Ling Xu, Renate A Weizbauer, Mathew G. Lewsey, José M. Palma, R. Glen Uhrig, Asela J. Wijeratne, Maria J. Harrison, William P Dwyer, Alexander T. Borowsky, Yuling Jiao, Kaushal Kumar Bhati, Edoardo Bertolini, Anna Stepanova, Francisco J. Corpas, Fabio Zanini, Pubudu P. Handakumbura, Dominique C. Bergmann, Devang Mehta, Saroj K Sah, Naomi Nakayama, Claire D McWhite, Jahed Ahmed, Dhruv Lavania, Gazala Ameen, Mather A Khan, Marc Libault, Gergo Palfalvi, Seung Y. Rhee, Laura E. Bartley, Vaishali Arora, Cesar L. Cuevas-Velazquez, Josh T. Cuperus, Benjamin Buer, Amir H. Ahkami, Lachezar A. Nikolov, Selena L Rice, Feng Zhao, Ronelle Roth, Ajay Kumar, Atique ur Rehman, Andrew Farmer, Maida Romera-Branchat, Zhi-Yong Wang, Tuan M Tran, Lydia-Marie Joubert, Le Liu, Julia Bailey-Serres, Fabio Gomez-Cano, Ramin Yadegari, Sanjay Joshi, James Whelan, Batthula Vijaya Lakshmi Vadde, Rachel Shahan, Houlin Yu, Bao-Hua Song, Andrey V Malkovskiy, Arun Kumar, Aaron J. Ogden, Javier Brumos, Xiaohong Zhuang, Oluwafemi Alaba, Harmanpreet Kaur, Tatsuya Nobori, Marisa S. Otegui, Peter H Denolf, Miguel Miñambres Martín, Sakil Mahmud, Tingting Xiang, Lisa I David, Justin W. Walley, Purva Karia, Maite Saura-Sanchez, Pankaj Kumar, Jamie Waese, Ansul Lokdarshi, Suryatapa Ghosh Jha, Sagar Kumar, Matthew M. S. Evans, Hai Ying Yuan, Rajveer Singh, Puneet Paul, Carly A Martin, Robert E. Jinkerson, Dianyi Liu, Rajdeep S. Khangura, Dae Kwan Ko, Tedrick Thomas Salim Lew, Jennifer A N Brophy, Ari Pekka Mähönen, Marija Vidović, Mark-Christoph Ott, Alok Arun, Pinky Agarwal, Pradeep Kumar, Alexandre P. Marand, R. Clay Wright, Moises Exposito-Alonso, Rosangela Sozzani, Tamas Varga, Luigi Di Costanzo, Shyam Solanki, Sixue Chen, Chien-Yuan Lin, Iain C. Macaulay, Tie Liu, Elsa H Quezada-Rodríguez, Trevor M. Nolan, Peter Denolf, Stefania Giacomello, Elizabeth S. Haswell, Nancy George, Noel Blanco-Touriñán, Bruno Contreras-Moreira, Benjamin J. Cole, Abhishek Joshi, Steven P. Briggs, Toshihiro Obata, Kerstin Kaufmann, Kenneth D. Birnbaum, Klaas J. van Wijk, Noah Fahlgren, Kamal Kumar Malukani, Ramesh Katam, Pingtao Ding, Mario A. Arteaga-Vazquez, Marcela K. Tello-Ruiz, Shao-shan Carol Huang, Sunil Kumar Kenchanmane Raju, Venura Herath, George W. Bassel, Christopher R. Anderton, Stefan de Folter, Gary Stacey, Jie Zhu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e07ab6c78004de66a9d276c061e8784b
https://doi.org/10.7554/elife.66877.sa2
https://doi.org/10.7554/elife.66877.sa2
Autor:
Paul L. Bollyky, Sean P. Ryan, Alexander A. Yacob, Colleen Dunn, Carlos Milla, Jacquelyn Zirbes, Jayakumar Rajadas, Andrey V. Malkovskiy
Publikováno v:
Analytical Chemistry. 91:7929-7934
Improved methods are needed to reliably assess Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) function in vivo in light of recent therapeutic developments targeting the CFTR protein. Oral fluid from patients with cystic fibrosis (CF) and
Autor:
Irina Gurevich, Jayakumar Rajadas, Adam Frymoyer, Wenchao Sun, Andrey V. Malkovskiy, Jens W. Fischer, Gernot Kaber, Bryan J. Xie, Nadine Nagy, Paul L. Bollyky, Payton L. Marshall, Hedwich F. Kuipers, Maria Grandoch, Shannon M. Ruppert
Publikováno v:
J Biol Chem
4-Methylumbelliferone (4-MU) inhibits hyaluronan (HA) synthesis and is an approved drug used for managing biliary spasm. However, rapid and efficient glucuronidation is thought to limit its utility for systemically inhibiting HA synthesis. In particu
Autor:
Che-Hong Chen, Andrey V. Malkovskiy, Jayakumar Rajadas, Bradley Efron, Lauren D. Van Wassenhove, Kwame Osei-Sarfo, Daria Mochly-Rosen, Lorraine J. Gudas, Yury Goltsev
Publikováno v:
Calcified tissue international, vol 108, iss 2
Calcif Tissue Int
Calcif Tissue Int
ALDH2 inactivating mutation (ALDH2*2) is the most abundant mutation leading to bone morphological aberration. Osteoporosis has long been associated with changes in bone biomaterial in elderly populations. Such changes can be exacerbated with elevated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03fcfd34c1315e7ab232033dfb94df11
https://escholarship.org/uc/item/85f5h3wz
https://escholarship.org/uc/item/85f5h3wz
Autor:
George W. Bassel, Claire D McWhite, Dhruv Lavania, Gazala Ameen, Christopher R. Anderton, Rajiv K. Tripathi, Maria J. Harrison, Josh T. Cuperus, Amir H. Ahkami, William P Dwyer, Bao-Hua Song, Fabio Zanini, Miguel Miñambres Martín, Atique ur Rehman, Cesar L. Cuevas-Velazquez, Ari Pekka Mähönen, Tamas Varga, Gergo Palfalvi, Andrew Farmer, Matthew M. S. Evans, Vaishali Arora, Uwe John, Mathew G. Lewsey, Dominique C. Bergmann, Selena L Rice, Mario A. Arteaga-Vazquez, Dae Kwan Ko, Tedrick Thomas Salim Lew, Jennifer A N Brophy, Jenny C Mortimer, Marc Libault, Bruno Contreras-Moreira, Benjamin J. Cole, Naomi Nakayama, Marcela K. Tello-Ruiz, Ronelle Roth, Laura E. Bartley, Tingting Xiang, Benjamin Buer, Shyam Solanki, Nicolas L. Taylor, Feng Zhao, Shao-shan Carol Huang, Alok Arun, Pinky Agarwal, Marisa S. Otegui, Arun Kumar, Marija Vidović, Pankaj Kumar, Aaron J. Ogden, Sagar Kumar, Puneet Paul, Sergio Alan Cervantes-Pérez, Purva Karia, Stefan de Folter, Kerstin Kaufmann, Gary Stacey, Le Liu, Robert E. Jinkerson, Javier Brumos, Harmanpreet Kaur, Tatsuya Nobori, David W. Ehrhardt, Francisco J. Corpas, Steven P. Briggs, James Whelan, Batthula Vijaya Lakshmi Vadde, Peter H Denolf, Tie Liu, Kamal Kumar Malukani, Elsa H Quezada-Rodríguez, Jahed Ahmed, Hai Ying Yuan, Rajveer Singh, Trevor M. Nolan, Ramesh Katam, Mather A Khan, Jamie Waese, Toshihiro Obata, Ramin Yadegari, Lachezar A. Nikolov, Seung Y. Rhee, Luis C. Romero, Ajay Kumar, Kenneth D. Birnbaum, Nicholas J. Provart, Tuan M Tran, Sakil Mahmud, Maida Romera-Branchat, Pradeep Kumar, Saroj K Sah, Ai My Luong, Alexandre P. Marand, R. Clay Wright, Yana Kazachkova, Moises Exposito-Alonso, Klaas J. van Wijk, Noah Fahlgren, Peter Denolf, Fabio Gomez-Cano, Houlin Yu, Luigi Di Costanzo, Adrien Burlaocot, Alfredo Cruz-Ramírez, Pingtao Ding, Dianyi Liu, Renate A Weizbauer, Suryatapa Ghosh Jha, Jie Zhu, Pubudu P. Handakumbura, Kaushal Kumar Bhati, Edoardo Bertolini, Anna Stepanova, Rachel Shahan, Lisa I David, Justin W. Walley, Lydia-Marie Joubert, Nancy George, Sanjay Joshi, José M. Palma, Rosangela Sozzani, Mark-Christoph Ott, Sixue Chen, Ansul Lokdarshi, Sunil Kumar Kenchanmane Raju, Chien-Yuan Lin, Iain C. Macaulay, Venura Herath, Noel Blanco-Touriñán, Rajdeep S. Khangura, Zhi-Yong Wang, Alexander T. Borowsky, Julia Bailey-Serres, Andrey V Malkovskiy, Xiaohong Zhuang, Oluwafemi Alaba, Yuling Jiao, Abhishek Joshi, Devang Mehta, Maite Saura-Sanchez, Carly A Martin, Stefania Giacomello, Elizabeth S. Haswell, Shou-Ling Xu, R. Glen Uhrig, Asela J. Wijeratne
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
eLife
eLife, Vol 10 (2021)
instname
eLife
eLife, Vol 10 (2021)
With growing populations and pressing environmental problems, future economies will be increasingly plant-based. Now is the time to reimagine plant science as a critical component of fundamental science, agriculture, environmental stewardship, energy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dadb883d9c4e018a12e711f0ec4e83e
http://hdl.handle.net/10261/269271
http://hdl.handle.net/10261/269271
Autor:
Swastik Mishra, Nicoline M. Gappel, Michele Bonus, Andrey V. Malkovskiy, Michael M. Wudick, Martin J. Lercher, Debarati Basu, Elizabeth S. Haswell, Stephan Schott-Verdugo, Thomas J. Kleist, Mackenzie Machado, David W. Ehrhardt, Margaret Bezrutczyk, Wolf B. Frommer, Cosima S. A. Sies, Holger Gohlke, Edward E. Farmer, Thomas Hartwig, Jacob Moe-Lange
Publikováno v:
Science advances 7(37), eabg4298 (2021). doi:10.1126/sciadv.abg4298
Glutamate has dual roles in metabolism and signaling; thus, signaling functions must be isolatable and distinct from metabolic fluctuations, as seen in low-glutamate domains at synapses. In plants, wounding triggers electrical and calcium (Ca 2+ ) si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1840c5aa4c81f9cba06b3795ee7b9c3e
https://hdl.handle.net/2128/28626
https://hdl.handle.net/2128/28626