Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Andrey V. Kartashov"'
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0122198 (2015)
During activation, T cells integrate multiple signals from APCs and cytokine milieu. The blockade of these signals can have clinical benefits as exemplified by CTLA4-Ig, which blocks interaction of B7 co-stimulatory molecules on APCs with CD28 on T c
Externí odkaz:
https://doaj.org/article/fe63a8a0b62b49dda83b6cd9e2be20fe
Autor:
Hiroyuki Sasaki, Kris G. Alavattam, Ho-Su Sin, Masashi Yukawa, So Maezawa, Kazuteru Hasegawa, Artem Barski, Andrey V. Kartashov, Satoshi H. Namekawa, Akihiko Sakashita, Naoki Kubo
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 115, iss 19
Repressive H3K27me3 and active H3K4me2/3 together form bivalent chromatin domains, molecular hallmarks of developmental potential. In the male germline, these domains are thought to persist into sperm to establish totipotency in the next generation.
Autor:
Vincent A. Mukkada, Chang Zeng, Mirna Chehade, Sahiti Marella, Ting Wen, P.E. Putnam, Marc E. Rothenberg, Jason R. Spence, Catherine Ptaschinski, Anjaparavanda P. Naren, Artem Barski, Mark Rochman, Jianwen Que, Kavisha Arora, Simon P. Hogan, Taeko K. Noah, Lisa Waggoner, Lisa J. Martin, Jazib Uddin, Simone Vanoni, David Wu, Andrey V. Kartashov, Margaret H. Collins
Publikováno v:
J Allergy Clin Immunol
Background The pathology of eosinophilic esophagitis (EoE) is characterized by eosinophil-rich inflammation, basal zone hyperplasia (BZH), and dilated intercellular spaces, and the underlying processes that drive the pathologic manifestations of the
Autor:
Artem Barski, Max Costa, Yixin Yao, Thomas Kluz, Cynthia C. Jose, Suresh Cuddapah, Adriana Arita, Andrey V. Kartashov, Xiaoru Zhang, Hong Sun, Lakshmanan Jagannathan
Publikováno v:
Journal of Cellular Physiology. 231:1611-1620
Oxygen levels range from 2% to 9% in vivo. Atmospheric O2 levels (21%) are known to induce cell proliferation defects and cellular senescence in primary cell cultures. However, the mechanistic basis of the deleterious effects of higher O2 levels is n
Autor:
Matthew T. Weirauch, Sushmitha Vallabh, Andrey V. Kartashov, Xiaoting Chen, Sajjeev Jagannathan, Artem Barski, Masashi Yukawa
Publikováno v:
The Journal of Experimental Medicine
AP-1 transcription factor is recruited to the majority of chromatin remodeling sites during T cell activation. The activity of AP-1 is induced by co-stimulation and is required for chromatin opening. The sites of remodeling overlap with risk loci of
Autor:
Yrina, Rochman, Krista, Dienger-Stambaugh, Phoebe K, Richgels, Ian P, Lewkowich, Andrey V, Kartashov, Artem, Barski, Gurjit K, Khurana Hershey, Warren J, Leonard, Harinder, Singh
Publikováno v:
Science signaling. 11(521)
Pathogenic T helper 2 (T(H)2) cells, which produce increased amounts of the cytokines interleukin-5 (IL-5) and IL-13, promote allergic disorders, including asthma. Thymic stromal lymphopoietin (TSLP), a cytokine secreted by epithelial and innate immu
Autor:
Harinder Singh, Warren J. Leonard, Artem Barski, Andrey V. Kartashov, Phoebe K. Richgels, Krista Dienger-Stambaugh, Ian P. Lewkowich, Gurjit K. Khurana Hershey, Yrina Rochman
Publikováno v:
Science Signaling. 11
Pathogenic T helper 2 (T H 2) cells, which produce increased amounts of the cytokines interleukin-5 (IL-5) and IL-13, promote allergic disorders, including asthma. Thymic stromal lymphopoietin (TSLP), a cytokine secreted by epithelial and innate immu
Publikováno v:
Methods in Molecular Biology ISBN: 9781493978335
The massive amount of information produced by ChIP-Seq, RNA-Seq, and other next-generation sequencing-based methods requires computational data analysis. However, biologists performing these experiments often lack training in bioinformatics. BioWardr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf49dc58daf63020965571ccaa2c9861
https://europepmc.org/articles/PMC6188658/
https://europepmc.org/articles/PMC6188658/
Autor:
Patricia C. Fulkerson, Kaila L. Schollaert, Carine Bouffi, Andrey V. Kartashov, Xiaoting Chen, Matthew T. Weirauch, W. Clark Bacon, Artem Barski
Publikováno v:
The Journal of Immunology. 195:2683-2695
The production of mature eosinophils is a tightly orchestrated process with the aim to sustain normal eosinophil levels in tissues while also maintaining low numbers of these complex and sensitive cells in the blood. To identify regulators of homeost
Autor:
Kenneth D. Greis, Andrey V. Kartashov, Satoshi H. Namekawa, Fan Zhang, So Maezawa, Yosuke Ichijima, Kazuteru Hasegawa, Tyler J. Broering, Ho-Su Sin, Paul R. Andreassen, Artem Barski, Kris G. Alavattam, W. Clark Bacon
Publikováno v:
Developmental cell, vol 32, iss 5
SummaryGametogenesis is dependent on the expression of germline-specific genes. However, it remains unknown how the germline epigenome is distinctly established from that of somatic lineages. Here we show that genes commonly expressed in somatic line