Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Andrey V, Bortsov"'
Autor:
Andrey V. Bortsov, Marc Parisien, Samar Khoury, Amy E. Martinsen, Marie Udnesseter Lie, Ingrid Heuch, Kristian Hveem, John-Anker Zwart, Bendik S. Winsvold, Luda Diatchenko
Publikováno v:
PAIN Reports, Vol 7, Iss 5, p e1018 (2022)
Abstract. Introduction:. Back pain is the leading cause of disability worldwide. Although most back pain cases are acute, 20% of acute pain patients experience chronic back pain symptoms. It is unclear whether acute pain and chronic pain have similar
Externí odkaz:
https://doaj.org/article/7b12ab0c3da2446fa57ab4fb3968480c
Autor:
Sangsu Bang, Christopher R. Donnelly, Xin Luo, Maria Toro-Moreno, Xueshu Tao, Zilong Wang, Sharat Chandra, Andrey V. Bortsov, Emily R. Derbyshire, Ru-Rong Ji
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
GPR37 is expressed in macrophages, and has been implicated in resolution of inflammatory pain. Here the authors show that GPR37 can modulate sepsis in several animal models.
Externí odkaz:
https://doaj.org/article/eb825ea936f54c5198d6ef87a574a599
Publikováno v:
The Journal of Pain. 24:49-50
Autor:
Zilong Wang, Ru-Rong Ji, Wolfgang Liedtke, Andrey V. Bortsov, Kaiyuan Wang, Yong Chen, Michele Yeo, Maria I. Lioudyno, Qian Zeng, Changyu Jiang, Jorge Busciglio, Peng Wang, Sharat Chandra, Gang Chen
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature Communications
Nature Communications
Inhibitory GABA-ergic neurotransmission is fundamental for the adult vertebrate central nervous system and requires low chloride concentration in neurons, maintained by KCC2, a neuroprotective ion transporter that extrudes intracellular neuronal chlo
Autor:
Shad B. Smith, Andrey V. Bortsov, Andrea G. Nackley, William Maixner, Roger B. Fillingim, Aurelio A. Alonso, Thomas Buchheit, Luda Diatchenko, William E. Whitehead, Joel D. Greenspan, Richard Ohrbach, Inna E. Tchivileva, Sheila M. Gaynor, Richard L. Boortz-Marx, Wolfgang Liedtke, Jongbae Park, Eric Bair
Publikováno v:
Pain
Traditional classification and prognostic approaches for chronic pain conditions focus primarily on anatomically based clinical characteristics not based on underlying biopsychosocial factors contributing to perception of clinical pain and future pai
Autor:
Shad B. Smith, Tamar Sofer, Samuel A. McLean, Joel D. Greenspan, Dmitri V. Zaykin, Sarah D. Linnstaedt, Gary D. Slade, Hans Markus Munter, Luda Diatchenko, Richard Ohrbach, Marc Parisien, Eija Kalso, Jiwon Lee, Andrea G. Nackley, Tin Louie, Andrew S. Tungate, Mari A. Kaunisto, Samar Khoury, Andrey V. Bortsov, Pavel Gris, Qiao-Ping Wang, William Maixner, Roger B. Fillingim, G. Gregory Neely, Susan Redline
Publikováno v:
Sleep
Poor sleep quality can have harmful health consequences. Although many aspects of sleep are heritable, the understandings of genetic factors involved in its physiology remain limited. Here, we performed a genome-wide association study (GWAS) using th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6efec5e6d85300569af3799f2a10af9
http://hdl.handle.net/10138/335102
http://hdl.handle.net/10138/335102
Autor:
Mei-Chuan Ko, Temugin Berta, Andrea G. Nackley, Ouyang Chen, Sang Hoon Lee, Christopher R. Donnelly, Yul Huh, Zilong Wang, Kenta Furutani, Qianru He, Sangsu Bang, Andrey V. Bortsov, Yong Chen, Jasmine Ji, Ru-Rong Ji, Xin Luo, Xueshu Tao
Publikováno v:
Neuron. 109(17)
Although sex dimorphism is increasingly recognized as an important factor in pain, female-specific pain signaling is not well studied. Here we report that administration of IL-23 produces mechanical pain (mechanical allodynia) in female but not male
Autor:
Andrea G. Nackley, Wolfgang Liedtke, Anna Mae Diehl, Huiping Ding, Andreas E. Kremer, Johannes Morstein, Ana E. López-Romero, Qian Zeng, Zilong Wang, Ru-Rong Ji, Qiaojuan Zhang, Yong Chen, Xin Zhang, Piotr Milkiewicz, Tony E. Reeves, Sara L. Morales-Lázaro, Jennifer Y. Zhang, Marcin Krawczyk, Tamara Rosenbaum, Mei-Chuan Ko, Frank Lammert, Andrey V. Bortsov, Manal F. Abdelmalek, Michele Yeo, Huanghe Yang, Carlene Moore, Ying-Ai Jin
Publikováno v:
Gastroenterology. 161(1)
Background & Aims Limited understanding of pruritus mechanisms in cholestatic liver diseases hinders development of antipruritic treatments. Previous studies implicated lysophosphatidic acid (LPA) as a potential mediator of cholestatic pruritus. Meth
Autor:
Marie Udnesseter Lie, Ingrid Heuch, Hunt All-In Pain, Dmitri V. Zaykin, Samar Khoury, Bendik S. Winsvold, Luda Diatchenko, Marc Parisien, John-Anker Zwart, Amy E Martinsen, Andrey V. Bortsov, Kristian Hveem
Back pain is the leading cause of disability worldwide. Although most cases of back pain are acute, 20% of people with acute back pain go on to experience chronic back pain symptoms. It is unclear if acute and chronic pain states have similar or dist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::003639749cda6efd7aae855c5defb0b7
https://doi.org/10.1101/2020.09.04.20187575
https://doi.org/10.1101/2020.09.04.20187575
Publikováno v:
Anesthesiology. 133(3)
Background Voltage-gated sodium channel Nav1.7 has been validated as a perspective target for selective inhibitors with analgesic and anti-itch activity. The objective of this study was to discover new candidate compounds with Nav1.7 inhibitor proper