Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Andrey Postnov"'
Autor:
Maarten Ooms, Sofie Celen, Ronald De Hoogt, Ilse Lenaerts, Johnny Liebregts, Greet Vanhoof, Xavier Langlois, Andrey Postnov, Michel Koole, Alfons Verbruggen, Koen Van Laere, Guy Bormans
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 1, Iss 1, Pp 1-17 (2016)
Abstract Background Phosphodiesterase 10A (PDE10A) is an important regulator of nigrostriatal dopamine (DA) neurotransmission. However, little is known on the effect of alterations in DA neurotransmission on PDE10A availability. Here, we used [18F]JN
Externí odkaz:
https://doaj.org/article/d4dd4237d5784bcaae606d3049b031e4
Autor:
Gleb Danilov, Diana Kalaeva, Nina Vikhrova, Tatiana Konakova, Anna Zagorodnova, Angelina Popova, Andrey Postnov, Svetlana Shugay, Michael Shifrin, Igor Pronin
Publikováno v:
Caring is Sharing – Exploiting the Value in Data for Health and Innovation ISBN: 9781643683881
Nowadays, the quantitative analysis of PET/CT data in patients with glioblastoma is not strictly standardized in the clinic and does not exclude the human factor. This study aimed to evaluate the relationship between the radiomic features of glioblas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5ccb0ba463fb0fe691df10250095c8f
https://doi.org/10.3233/shti230320
https://doi.org/10.3233/shti230320
Autor:
Andrey Postnov, Jérôme Toutain, Igor Pronin, Samuel Valable, Fabienne Gourand, Diana Kalaeva, Nina Vikhrova, Elena Pyzhik, Stéphane Guillouet, Grigoriy Kobyakov, Ekaterina Khokholova, David Pitskhelauri, Dmitry Usachev, Sergey Maryashev, Marina Rizhova, Alexander Potapov, Jean-Michel Derlon
Publikováno v:
Clinical Nuclear Medicine. 47:699-706
This study sought to assess 18 F-fludarabine ( 18 F-FLUDA) PET/CT's ability in differentiating primary central nervous system lymphomas (PCNSLs) from glioblastoma multiformes (GBMs).Patients harboring either PCNSL (n = 8) before any treatment, PCNSL
Autor:
Sofie Celen, Jan de Hoon, Mark E. Schmidt, Guy Bormans, Stef Rassnick, Peter Zannikos, Darrel J. Pemberton, James A. Palmer, Andrey Postnov, Maarten van den Boer, Peter van der Ark, Koen Van Laere, Anne Van Hecken
Publikováno v:
Clinical and Translational Science. 11:397-404
Inhibition of fatty acid amide hydrolase (FAAH) potentiates endocannabinoid activity and is hypothesized to have therapeutic potential for mood and anxiety disorders and pain. The clinical profile of JNJ-42165279, an oral selective FAAH inhibitor, wa
Autor:
Jaap C. Reijneveld, Robert C. Schuit, Ronald Boellaard, Maqsood Yaqub, N. Harry Hendrikse, Jan J. Heimans, Patrick Schober, Andrey Postnov, Esther Bakker, Femke E. Froklage, Adriaan A. Lammertsma, Emile F.I. Comans, Demetrios N. Velis, Rob A. Voskuyl, Jack Zwemmer
Publikováno v:
Journal of Cerebral Blood Flow and Metabolism, 37(1), 97-105. Nature Publishing Group
Froklage, F E, Postnov, A, Yaqub, M M, Bakker, E, Boellaard, R, Harry Hendrikse, N, Comans, E F I, Schuit, R C, Schober, P, Velis, D N, Zwemmer, J, Heimans, J J, Lammertsma, A A, Voskuyl, R A & Reijneveld, J C 2017, ' Altered GABA A receptor density and unaltered blood-brain barrier [ 11 C]flumazenil transport in drug-resistant epilepsy patients with mesial temporal sclerosis ', Journal of Cerebral Blood Flow and Metabolism, vol. 37, no. 1, pp. 97-105 . https://doi.org/10.1177/0271678X15618219
Journal of Cerebral Blood Flow & Metabolism
Froklage, F E, Postnov, A, Yaqub, M M, Bakker, E, Boellaard, R, Harry Hendrikse, N, Comans, E F I, Schuit, R C, Schober, P, Velis, D N, Zwemmer, J, Heimans, J J, Lammertsma, A A, Voskuyl, R A & Reijneveld, J C 2017, ' Altered GABA A receptor density and unaltered blood-brain barrier [ 11 C]flumazenil transport in drug-resistant epilepsy patients with mesial temporal sclerosis ', Journal of Cerebral Blood Flow and Metabolism, vol. 37, no. 1, pp. 97-105 . https://doi.org/10.1177/0271678X15618219
Journal of Cerebral Blood Flow & Metabolism
Studies in rodents suggest that flumazenil is a P-glycoprotein substrate at the blood–brain barrier. This study aimed to assess whether [11C]flumazenil is a P-glycoprotein substrate in humans and to what extent increased P-glycoprotein function in
Autor:
Bart De Geest, Joseph Pierre Aboumsallem, Mudit Mishra, Andrey Postnov, Olivier Gheysens, Ilayaraja Muthuramu
Publikováno v:
Aging (Albany NY)
Epidemiological studies support a strong association between non-high-density lipoprotein cholesterol levels and heart failure incidence. The objective of the current study was to evaluate the effect of selective cholesterol lowering adeno-associated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6d6aeafb6683f2980121b180055c714
https://lirias.kuleuven.be/handle/123456789/656724
https://lirias.kuleuven.be/handle/123456789/656724
Autor:
Cindy Casteels, Bart de Laat, Sofie Celen, Koen Van Laere, Michel Koole, Guy Bormans, Gil Leurquin-Sterk, Andrey Postnov, Cleo L. Crunelle
Publikováno v:
Synapse. 70:153-162
(18)F-FPEB is a promising PET tracer for studying the metabotropic glutamate subtype 5 receptor (mGluR5) expression in neuropsychiatric disorders. To assess the potential of (18)F-FPEB for longitudinal mGluR5 evaluation in patient studies, we evaluat
Autor:
Bart N.M. van Berckel, Albert D. Windhorst, Esther Bakker, Jaap C. Reijneveld, Ronald Boellaard, N. Harry Hendrikse, Andrey Postnov, Femke E. Froklage, Adriaan A. Lammertsma, Robert C. Schuit, Patrick Schober
Publikováno v:
Journal of Nuclear Medicine, 56(11), 1730-1735. Society of Nuclear Medicine Inc.
Froklage, E A M, Boellaard, R, Bakker, E N, Hendrikse, N H, Reijneveld, J C, Schuit, R C, Windhorst, A D, Schober, P, van Berckel, B N M, Lammertsma, A A & Postnov, A 2015, ' Quantification of C-11-Laniquidar Kinetics in the Brain ', Journal of Nuclear Medicine, vol. 56, no. 11, pp. 1730-1735 . https://doi.org/10.2967/jnumed.115.157586
Froklage, E A M, Boellaard, R, Bakker, E N, Hendrikse, N H, Reijneveld, J C, Schuit, R C, Windhorst, A D, Schober, P, van Berckel, B N M, Lammertsma, A A & Postnov, A 2015, ' Quantification of C-11-Laniquidar Kinetics in the Brain ', Journal of Nuclear Medicine, vol. 56, no. 11, pp. 1730-1735 . https://doi.org/10.2967/jnumed.115.157586
Overexpression of the multidrug efflux transport P-glycoprotein may play an important role in pharmacoresistance. 11C-laniquidar is a newly developed tracer of P-glycoprotein expression. The aim of this study was to develop a pharmacokinetic model fo
Autor:
Jan de Hoon, Michael Klimas, Manu Chakravarthy, Christophe Deroose, Ruben Declercq, Inge De Lepeleire, Corinne Vandermeulen, Andrey Postnov, Justin Dennie, Olivier Gheysens, Koen Van Laere, Lori A. Mixson
Publikováno v:
Journal of Nuclear Medicine. 56:1520-1526
The quantification and variability of skeletal muscle glucose utilization (SMGU) in healthy subjects under basal (low insulin) conditions are poorly known. This information is essential early in clinical drug development to effectively interrogate no
Autor:
Andrey, Postnov, Mark E, Schmidt, Darrel J, Pemberton, Jan, de Hoon, Anne, van Hecken, Maarten, van den Boer, Peter, Zannikos, Peter, van der Ark, James A, Palmer, Stef, Rassnick, Sofie, Celen, Guy, Bormans, Koen, van Laere
Publikováno v:
Clinical and Translational Science
Inhibition of fatty acid amide hydrolase (FAAH) potentiates endocannabinoid activity and is hypothesized to have therapeutic potential for mood and anxiety disorders and pain. The clinical profile of JNJ‐42165279, an oral selective FAAH inhibitor,