Zobrazeno 1 - 10 of 10 pro vyhledávání: '"Andrey Pokrovsky"'
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Akademický článek
Design, Synthesis, and Molecular Docking Study of New Tyrosyl-DNA Phosphodiesterase 1 (TDP1) Inhibitors Combining Resin Acids and Adamantane Moieties
Autor: Kseniya Kovaleva, Olga Yarovaya, Konstantin Ponomarev, Sergey Cheresiz, Amirhossein Azimirad, Irina Chernyshova, Alexandra Zakharenko, Vasily Konev, Tatiana Khlebnikova, Evgenii Mozhaytsev, Evgenii Suslov, Dmitry Nilov, Vytas Švedas, Andrey Pokrovsky, Olga Lavrik, Nariman Salakhutdinov
Publikováno v: Pharmaceuticals, Vol 14, Iss 5, p 422 (2021)
In this paper, a series of novel abietyl and dehydroabietyl ureas, thioureas, amides, and thioamides bearing adamantane moieties were designed, synthesized, and evaluated for their inhibitory activities against tyrosil-DNA-phosphodiesterase 1 (TDP1).
Externí odkaz: https://doaj.org/article/77553d11944b4a27a2b62c58064feea5
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Antisense activity of an anti-HIV oligonucleotide conjugated to linear and branched high molecular weight polyethylene glycols
Autor: Andrey Pokrovsky, FrancescoMaria Veronese, Olga Pliasunova, Simone Zaramella, GianMaria Bonora, Graziella Tocco, Valentina F. Zarytova, Eugenia M. Ivanova
Publikováno v: Farmaco (Societa chimica italiana : 1989). 53(10-11)
An anti-HIV 12mer oligonucleotide (ODN) conjugated to two different high molecular weight monomethoxy polyethylene glycols (MPEGs) has been tested for its antisense activity. The capacity of these conjugates to protect the MT-4 cells against HIV infe
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c350cc0a65251193eae0fc2891c181a0
https://pubmed.ncbi.nlm.nih.gov/10205850
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