Distinct distribution of ectopically expressed histone variants H2A.Bbd and MacroH2A in open and closed chromatin domains.

Autor: Elena S Ioudinkova, Ana Barat, Andrey Pichugin, Elena Markova, Ilya Sklyar, Iryna Pirozhkova, Chloe Robin, Marc Lipinski, Vasily Ogryzko, Yegor S Vassetzky, Sergey V Razin

Publikováno v: PLoS ONE, Vol 7, Iss 10, p e47157 (2012)

BACKGROUND:It becomes increasingly evident that nuclesomes are far from being identical to each other. This nucleosome diversity is due partially to the existence of histone variants encoded by separate genes. Among the known histone variants the les

Externí odkaz: https://doaj.org/article/ab25aa0999524a24b0288e6fa52ba604

Development and assessment of herpes simplex virus type 1 (HSV-1) amplicon vectors with sensory neuron-selective promoters

Autor: Charles Joussain, Olivier Le Coz, Andrey Pichugin, Peggy Marconi, Filip Lim, Mariaconcetta Sicurella, Keith Foster, François Giuliano, Alberto L. Epstein, Alejandro Aranda Muñoz

Publikováno v: International Journal of Molecular Sciences; Volume 23; Issue 15; Pages: 8474

Background: Neurogenic detrusor overactivity (NDO) is a severe pathological condition characterized by involuntary detrusor contractions leading to urine leakage. This condition is frequent after spinal cord injury (SCI). Gene therapy for NDO require

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f3b35df91e81a96971612a8f4d38434
https://doi.org/10.3390/ijms23158474

Nuclear localization of translocation partners in differentiating B-cells

Autor: I. V. Sklyar, E. S. Vassetzky, Olga V. Iarovaia, Sergey V. Razin, Andrey Pichugin

Publikováno v: Doklady Biochemistry and Biophysics. 464:312-314

We studied the nuclear localization and relative position in the nuclear space of malignant translocation partner genes c-Myc, CCND1, and IGH locus in naive and differentiating B cells. We have shown that, during B-cell maturation, c-Myc and IGH loci

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99d991f8d9cfb08a21ef0edb9d1ddac8
https://doi.org/10.1134/s1607672915050129

Distinct Patterns of Colocalization of the CCND1 and CMYC Genes With Their Potential Translocation Partner IGH at Successive Stages of B-Cell Differentiation

Autor: Ilya, Sklyar, Olga V, Iarovaia, Alexey A, Gavrilov, Andrey, Pichugin, Diego, Germini, Tatiana, Tsfasman, Gersende, Caron, Thierry, Fest, Marc, Lipinski, Sergey V, Razin, Yegor S, Vassetzky

Publikováno v: Journal of Cellular Biochemistry
Journal of Cellular Biochemistry, Wiley, 2016, 117 (7), pp.1506-1510. ⟨10.1002/jcb.25516⟩
Journal of Cellular Biochemistry, 2016, 117 (7), pp.1506-1510. ⟨10.1002/jcb.25516⟩

The immunoglobulin heavy chain (IGH) locus is submitted to intra-chromosomal DNA breakages and rearrangements during normal B cell differentiation that create a risk for illegitimate inter-chromosomal translocations leading to a variety of B-cell mal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::aca6eedfa2738c4eb8698c7b604a87fb
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01295670

Dynamics of constitutive heterochromatin: two contrasted kinetics of genome restructuring in early cloned bovine embryos

Autor: Gaetan Lehmann, Jean Paul Renard, Nathalie Beaujean, Pierre Adenot, Xavier Vignon, Andrey Pichugin, Christophe Audouard, Daniel Le Bourhis

Publikováno v: Reproduction
Reproduction, BioScientifica, 2010, 139 (1), pp.129-137. ⟨10.1530/REP-08-0435⟩

International audience; Efficient reprograming of the donor cell genome in nuclear transfer (NT) embryos is linked to the ability of the embryos to sustain full-term development. As the nuclear architecture has recently emerged as a key factor in the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99f371ec3b19ddee654469afe77a8964
https://doi.org/10.1530/rep-08-0435