Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Andrey M. Leontovich"'
Autor:
Alexander E. Gorbalenya, Leo L.M. Poon, Chris Lauber, Benjamin W. Neuman, Dmitry V. Samborskiy, Anastasia A. Gulyaeva, Igor A. Sidorov, John Ziebuhr, Andrey M. Leontovich, Christian Drosten, Susan C. Baker, Dmitry Penzar, Raoul J. de Groot, Bart L. Haagmans, Ralph S. Baric, Isabel Solá Gurpegui, Stanley Perlman
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
Publicado en Nature Microbiology (doi: 10.1038/s41564-020-0695-z) http://hdl.handle.net/10261/213002
The present outbreak of lower respiratory tract infections, including respiratory distress syndrome, is the third spillover, in only two decades
The present outbreak of lower respiratory tract infections, including respiratory distress syndrome, is the third spillover, in only two decades
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bf16ca1b0cffd0f2e19a2fc93b250c6
http://hdl.handle.net/10261/212994
http://hdl.handle.net/10261/212994
Autor:
Dmitry V. Samborskiy, Eric J. Snijder, Mark Ruben, Peter A. van Veelen, George M.C. Janssen, Anastasia A. Gulyaeva, Igor A. Sidorov, Alexander E. Gorbalenya, Hermen S. Overkleeft, Kathleen C. Lehmann, Andrey M. Leontovich, Alexander A. Kravchenko, Jessika C. Zevenhoven-Dobbe, Clara C. Posthuma
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, 43(17), 8416-8434
Nucleic Acids Research, 43(17), 8416-8434
RNA viruses encode an RNA-dependent RNA polymerase (RdRp) that catalyzes the synthesis of their RNA(s). In the case of positive-stranded RNA viruses belonging to the order Nidovirales, the RdRp resides in a replicase subunit that is unusually large.
Autor:
Chris Lauber, Kalina T. Zlateva, Willy J. M. Spaan, Alexander E. Gorbalenya, Alexander A. Kravchenko, Eric C. J. Claas, Kelly M. Crusio, Andrey M. Leontovich
Publikováno v:
Journal of Virological Methods
Journal of Virological Methods, 177(2), 174-183
Journal of Virological Methods, 177(2), 174-183
Highlights ► We developed one-step RT-PCR assay to recognize corona- and toroviruses. ► It utilizes consensus-degenerated hybrid oligonucleotide primers. ► The primers were targeted to RNA-dependent RNA polymerase locus. ► Assay recognized vi
Autor:
K. Yu. Tokmachev, Andrey M. Leontovich
Publikováno v:
Biophysics. 51:527-534
Modifications for improving the prediction quality in a previously described adaptive algorithm of automated annotation (A 4) were considered. First, the direct use of the basis statistic η ensures a higher prediction quality than the use of a previ
Publikováno v:
Bioinformatics. 18:838-844
Motivation: It is common knowledge that the avalanche of data arriving from the sequencing projects cannot be annotated either experimentally or manually by experts. The need for a reliable and convenient tool for automated sequence annotation is bro
Autor:
Igor A. Sidorov, Alexander E. Gorbalenya, T. Alwyn Jones, Andrey M. Leontovich, Dmitry V. Samborskiy, Bruno Canard, Philippe Lieutaud, Bruno Coutard, Mark Harris, Alexander A. Kravchenko, Gerard J. Kleywegt
Publikováno v:
Antiviral Research, 87(2), 95-110
Antiviral Research
Antiviral Research
This review focuses on bioinformatics technologies employed by the EU-sponsored multidisciplinary VIZIER consortium (Comparative Structural Genomics of Viral Enzymes Involved in Replication, FP6 Project: 2004-511960, active from 1 November 2004 to 30
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a3e2defd46ffed36e7bfe8b890f6d82
https://hdl.handle.net/1887/88135
https://hdl.handle.net/1887/88135
Autor:
Paul A. Tucker, P. La Colla, Rémi N. Charrel, Ernest A. Gould, Helene Norder, Torsten Unge, Johan Neyts, Eric J. Snijder, Boris Klempa, Jacques Rohayem, Bruno Coutard, Martino Bolognesi, G. Puerstinger, X. de Lamballerie, Jean-Paul Gonzalez, Anne Poupon, Pär Nordlund, Gérard Bricogne, Jean-Louis Romette, T.A. Jones, Andrey M. Leontovich, Jonathan M. Grimes, Andrea Mattevi, Stephan Günther, Rolf Hilgenfeld, Hervé Bourhy, Christian Cambillau, Raymond J. Owens, Johan Åqvist, David I. Stuart, Miquel Coll, E. L’hermite, Alexander E. Gorbalenya, Bruno Canard, Eric M. Leroy
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Antiviral Research
instname
Antiviral Research
Coutard, B. et al.
Life-threatening RNA viruses emerge regularly, and often in an unpredictable manner. Yet, the very few drugs available against known RNA viruses have sometimes required decades of research for development. Can we generate prep
Life-threatening RNA viruses emerge regularly, and often in an unpredictable manner. Yet, the very few drugs available against known RNA viruses have sometimes required decades of research for development. Can we generate prep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::032159b157d0f5bc8841a99c001e6d78
http://hdl.handle.net/10261/109018
http://hdl.handle.net/10261/109018
Publikováno v:
BMC Bioinformatics
BMC Bioinformatics, Vol 9, Iss 1, p 31 (2008)
BMC Bioinformatics, Vol 9, Iss 1, p 31 (2008)
Background This paper discusses the problem of automated annotation. It is a continuation of the previous work on the A4-algorithm (Adaptive algorithm of automated annotation) developed by Leontovich and others. Results A number of new statistics for
Publikováno v:
Bio Systems. 30(1-3)
A novel algorithm for construction of complete maps of local similarity for two biopolymer sequences is described. The algorithm is much faster than the related Altschul-Erickson procedure, it is implemented as the Dot-Helix module within the GeneBee