Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Andrey G. Tereshchenkov"'
Autor:
Inna A. Volynkina, Elena N. Bychkova, Anastasiia O. Karakchieva, Alexander S. Tikhomirov, George V. Zatonsky, Svetlana E. Solovieva, Maksim M. Martynov, Natalia E. Grammatikova, Andrey G. Tereshchenkov, Alena Paleskava, Andrey L. Konevega, Petr V. Sergiev, Olga A. Dontsova, Ilya A. Osterman, Andrey E. Shchekotikhin, Anna N. Tevyashova
Publikováno v:
Pharmaceuticals, Vol 17, Iss 2, p 187 (2024)
The sustained rise of antimicrobial resistance (AMR) causes a strong need to develop new antibacterial agents. One of the methods for addressing the problem of antibiotic resistance is through the design of hybrid antibiotics. In this work, we propos
Externí odkaz:
https://doaj.org/article/807737912d584410b6286cfbdcf876e1
Autor:
Andrey G. Tereshchenkov, Zimfira Z. Khairullina, Inna A. Volynkina, Dmitrii A. Lukianov, Pavel A. Nazarov, Julia A. Pavlova, Vadim N. Tashlitsky, Elizaveta A. Razumova, Daria A. Ipatova, Yury V. Timchenko, Dmitry A. Senko, Olga V. Efremenkova, Alena Paleskava, Andrey L. Konevega, Ilya A. Osterman, Igor A. Rodin, Petr V. Sergiev, Olga A. Dontsova, Alexey A. Bogdanov, Natalia V. Sumbatyan
Publikováno v:
Pharmaceutics, Vol 16, Iss 1, p 148 (2024)
Antimicrobial peptides (AMPs) have recently attracted attention as promising antibacterial agents capable of acting against resistant bacterial strains. In this work, an approach was applied, consisting of the conjugation of a peptide related to the
Externí odkaz:
https://doaj.org/article/070a9d24e6dc4c41b6503f6e3a7c5d29
Autor:
Julia A. Pavlova, Andrey G. Tereshchenkov, Pavel A. Nazarov, Dmitrii A. Lukianov, Dmitry A. Skvortsov, Vladimir I. Polshakov, Byasilya F. Vasilieva, Olga V. Efremenkova, Mikhail Y. Kaiumov, Alena Paleskava, Andrey L. Konevega, Olga A. Dontsova, Ilya A. Osterman, Alexey A. Bogdanov, Natalia V. Sumbatyan
Publikováno v:
Antibiotics, Vol 12, Iss 1, p 15 (2022)
In order to obtain antimicrobial compounds with improved properties, new conjugates comprising two different biologically active agents within a single chimeric molecule based on chloramphenicol (CHL) and a hydrophobic cation were synthesized and stu
Externí odkaz:
https://doaj.org/article/a605ba928b33422cadcd2b7d2d8bc6a5
Autor:
Chih-Wei Chen, Julia A. Pavlova, Dmitrii A. Lukianov, Andrey G. Tereshchenkov, Gennady I. Makarov, Zimfira Z. Khairullina, Vadim N. Tashlitsky, Alena Paleskava, Andrey L. Konevega, Alexey A. Bogdanov, Ilya A. Osterman, Natalia V. Sumbatyan, Yury S. Polikanov
Publikováno v:
Antibiotics, Vol 10, Iss 4, p 390 (2021)
Chloramphenicol (CHL) is a ribosome-targeting antibiotic that binds to the peptidyl transferase center (PTC) of the bacterial ribosome and inhibits peptide bond formation. As an approach for modifying and potentially improving the properties of this
Externí odkaz:
https://doaj.org/article/3bcc4395e05d4903a35a3ea5653542a7
Autor:
Julia A. Pavlova, Zimfira Z. Khairullina, Andrey G. Tereshchenkov, Pavel A. Nazarov, Dmitrii A. Lukianov, Inna A. Volynkina, Dmitry A. Skvortsov, Gennady I. Makarov, Etna Abad, Somay Y. Murayama, Susumu Kajiwara, Alena Paleskava, Andrey L. Konevega, Yuri N. Antonenko, Alex Lyakhovich, Ilya A. Osterman, Alexey A. Bogdanov, Natalia V. Sumbatyan
Publikováno v:
Antibiotics, Vol 10, Iss 5, p 489 (2021)
In the current work, in continuation of our recent research, we synthesized and studied new chimeric compounds, including the ribosome-targeting antibiotic chloramphenicol (CHL) and the membrane-penetrating cation triphenylphosphonium (TPP), which ar
Externí odkaz:
https://doaj.org/article/d7e64d55801f418cb67a84cf4c2c37fb
Autor:
Zimfira Z. Khairullina, Gennady I. Makarov, Andrey G. Tereshchenkov, Vitaly S. Buev, Dmitrii A. Lukianov, Vladimir I. Polshakov, Vadim N. Tashlitsky, Ilya A. Osterman, Natalia V. Sumbatyan
Publikováno v:
Biochemistry. Biokhimiia. 87(9)
Design and synthesis of conjugates consisting of the macrolide antibiotic desmycosin and fragments of the antibacterial peptide oncocin were performed in attempt to develop new antimicrobial compounds. New compounds were shown to bind to the E. coli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aed2d405e30bd4d4d00661ff32ee9f06
https://pubmed.ncbi.nlm.nih.gov/36180983
https://pubmed.ncbi.nlm.nih.gov/36180983
Autor:
Ekaterina S. Komarova, Andrey G Tereshchenkov, Petr V. Sergiev, Dmitrii I. Shiriaev, Ilya A. Osterman, Alexander G. Myasnikov, Andrey L. Konevega, Yury S. Polikanov, Evgeny Pichkur, Alexey A. Bogdanov, Alena Paleskava, Pavel Kasatsky, Olga A. Dontsova
Publikováno v:
RNA
RNA, 2020, 26 (6), pp.715-723. ⟨10.1261/rna.073817.119⟩
RNA, 2020, 26 (6), pp.715-723. ⟨10.1261/rna.073817.119⟩
Macrolides are one of the most successful and widely used classes of antibacterials, which kill or stop the growth of pathogenic bacteria by binding near the active site of the ribosome and interfering with protein synthesis. Dirithromycin is a deriv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bb47f950d0f0c201a0d26d32bc559d4
https://doi.org/10.1261/rna.073817.119
https://doi.org/10.1261/rna.073817.119
Autor:
Andrey L. Konevega, Zimfira Z Khairullina, Yury S. Polikanov, Andrey G Tereshchenkov, Alexey A. Bogdanov, Vadim N. Tashlitsky, G. I. Makarov, Julia A. Pavlova, Natalia V. Sumbatyan, Chih-Wei Chen, Dmitrii A. Lukianov, Alena Paleskava, Ilya A. Osterman
Publikováno v:
Antibiotics
Volume 10
Issue 4
Antibiotics, Vol 10, Iss 390, p 390 (2021)
Volume 10
Issue 4
Antibiotics, Vol 10, Iss 390, p 390 (2021)
Chloramphenicol (CHL) is a ribosome-targeting antibiotic that binds to the peptidyl transferase center (PTC) of the bacterial ribosome and inhibits peptide bond formation. As an approach for modifying and potentially improving the properties of this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::043e9834cda0350a56c59bd54f5e9bc2
Autor:
Alena Paleskava, Etna Abad, Ilya A. Osterman, Pavel A. Nazarov, G. I. Makarov, Susumu Kajiwara, Yuri N. Antonenko, Dmitrii A. Lukianov, Zimfira Z Khairullina, Inna A. Volynkina, Julia A. Pavlova, Somay Y Murayama, Alex Lyakhovich, Dmitry A. Skvortsov, Natalia V. Sumbatyan, Andrey G Tereshchenkov, Alexey A. Bogdanov, Andrey L. Konevega
Publikováno v:
Antibiotics, Vol 10, Iss 489, p 489 (2021)
Scientia
Antibiotics
Volume 10
Issue 5
Scientia
Antibiotics
Volume 10
Issue 5
Activitat antibiòtica; Ribosoma bacterià; Simulacions de dinàmica molecular Actividad antibiótica; Ribosoma bacteriano; Simulaciones de dinámica molecular Antibiotic activity; Bacterial ribosome; Molecular dynamics simulations In the current wor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66a4c290144f8152e662a507a775c0e1
https://www.mdpi.com/2079-6382/10/5/489
https://www.mdpi.com/2079-6382/10/5/489
Autor:
Ilya A. Osterman, S A Zavyalova, Ekaterina S. Komarova, Andrey G Tereshchenkov, N.V. Sumbatyan, Vadim N. Tashlitsky, Zimfira Z Khairullina, Dmitrii A. Lukianov
Publikováno v:
Biochemistry. Biokhimiia. 85(11)
Virtual screening of all possible tripeptide analogues of chloramphenicol was performed using molecular docking to evaluate their affinity to bacterial ribosomes. Chloramphenicol analogues that demonstrated the lowest calculated energy of interaction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82a92ee45429e736d27bb7d99cca334b
https://pubmed.ncbi.nlm.nih.gov/33280584
https://pubmed.ncbi.nlm.nih.gov/33280584