Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Andrey Alexandrovich Ivashchenko"'
Autor:
Stanislav V Poyarkov, Natalia V Krivonos, Elena N Simakina, Olga S Rosinkova, Elena A. Merkulova, Nikolay Filippovich Savchuk, Dmitry V. Kravchenko, Alina N. Egorova, Valeria N Azarova, Elena V Yakubova, Ruben N. Karapetian, Alexandre V. Ivachtchenko, Mikhail A Topr, Andrey Alexandrovich Ivashchenko, Vladimir G Loginov
Publikováno v:
Viruses, Vol 13, Iss 1253, p 1253 (2021)
Viruses
Viruses
COVID-19 is a contagious multisystem inflammatory disease caused by a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We studied the efficacy of Aprotinin (nonspecific serine proteases inhibitor) in combination with Avifavir® or Hydrox
Autor:
Elena A. Merkulova, Dmitriy S. Gorchakov, Oleg D. Mitkin, Nataliya A. Penchul, Alina N. Egorova, George E. Rupchev, Allan G. Beniashvily, Denis S. Burminskiy, Lala N. Kasimova, Ruben N. Karapetian, Natalia V. Vostokova, Lubov Y. Gluskina, Olga A. Bukhanovskaya, Margarita A. Morozova, Taissia A. Lepilkina, Dmitry V. Kravchenko, Andrey Alexandrovich Ivashchenko, Sergey S. Potanin, Alexandre V. Ivachtchenko
Publikováno v:
Journal of psychiatric research. 143
Generalized anxiety disorder (GAD) is associated with an imbalance in the functioning of the stimulating neurotransmitter systems in human's brain. We studied the safety and therapeutic efficacy of aviandr, the new noradrenergic and specific serotone
Autor:
Elena A Smolyarchuk, Natalia V. Vostokova, Andrew A. Blinow, Elena V Yakubova, Ruben N. Karapetian, Elena G. Tikhomolova, Nikolay Filippovich Savchuk, Tagir A. Sitdekov, Elena A. Merkulova, Kirill A. Dmitriev, Elena N Simakina, Elena P. Pavlikova, Valeria N Azarova, Natalia A. Papazova, Andrey Alexandrovich Ivashchenko, Alexandre V. Ivachtchenko, Alina N. Egorova, Nikita V. Lomakin, Dmitry V. Kravchenko, Alexey P. Ilin, Ivan G. Gordeev
Publikováno v:
Clinical Infectious Diseases
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
In May 2020 the Russian Ministry of Health granted fast-track marketing authorization to RNA polymerase inhibitor AVIFAVIR (favipiravir) for the treatment of COVID-19 patients. In the pilot stage of Phase II/III clinical trial, AVIFAVIR enabled SARS-
Autor:
Ivan G. Gordeev, Andrey Alexandrovich Ivashchenko, Alexey P. Ilin, Dmitry V. Kravchenko, Nikolay Filippovich Savchuk, Kirill A. Dmitriev, Nikita V. Lomakin, Elena V Yakubova, Ruben N. Karapetian, Elena G. Tikhomolova, Elena N Simakina, Elena A. Merkulova, Natalia V. Vostokova, Natalia A. Papazova, Elena A Smolyarchuk, Alexandre V. Ivachtchenko, Andrew A. Blinow, Elena P. Pavlikova, Tagir A. Sitdekov, Alina N. Egorova, Valeria N Azarova
In May 2020 the Russian Ministry of Health granted fast-track marketing authorization to RNA polymerase inhibitor AVIFAVIR (favipiravir) for the treatment of COVID-19 patients. In the pilot stage of Phase II/III clinical trial, AVIFAVIR enabled SARS-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee4c74b1b527e94b4d82f6b1475524f5
Autor:
Vladimir A. Aladinskiy, Ramiz Salimov, Alexandre V. Ivachtchenko, Angela G. Koryakova, Ruben Karapetyan, Ilya Bezprozvanny, Yan A. Ivanenkov, Oleg D. Mitkin, Ilya Okun, Andrey Alexandrovich Ivashchenko
Publikováno v:
Journal of Alzheimer's Disease. 58:1043-1063
Discovery of 5-HT6 receptor subtype and its exclusive localization within the central nervous system led to extensive investigations of its role in Alzheimer's disease, schizophrenia, and obesity. In the present study, we present preclinical evaluati
Autor:
Elena V Yakubova, Alexandre V. Ivachtchenko, Nikolay Filippovich Savchuk, Andrey Alexandrovich Ivashchenko
Publikováno v:
Clinical Infectious Diseases. 73:e848-e849
Autor:
Bogdan A. Zagribelnyy, Nikolai P. Savchuk, Yan A. Ivanenkov, Ruben N. Karapetian, Dmitry V. Kravchenko, Andrey Alexandrovich Ivashchenko, Angela G. Koryakova, Vladimir A. Aladinskiy, Alexey A Ryakhovskiy, Oleg D. Mitkin, Alexander Vasilievich Ivashchenko
Publikováno v:
Bioorganic & Medicinal Chemistry. 28:115716
A series of novel small-molecule pan-genotypic hepatitis C virus (HCV) NS5A inhibitors with picomolar activity containing 2-[(2S)-pyrrolidin-2-yl]-5-[4-(4-{2-[(2S)-pyrrolidin-2-yl]-1H-imidazol-5-yl}buta-1,3-diyn-1-yl)phenyl]-1H-imidazole core was des
Autor:
Andrey Alexandrovich Ivashchenko, Nikolai P. Savchuk, Alexander Vasilievich Ivashchenko, Ruben N. Karapetian, Dmitry V. Kravchenko, Oleg D. Mitkin, Angela G. Koryakova, Yan A. Ivanenkov, Vladimir A. Aladinskiy
Publikováno v:
European Journal of Medicinal Chemistry. 189:112064
Although a relatively wide range of therapeutic options is currently available for the treatment of HIV/AIDS, it is still among the most serious and virulent diseases and is associated with a high mortality rate. Integrase strand transfer inhibitors
Autor:
Pavel M. Yamanushkin, Elena A. Bulanova, O. M. Korzinov, Vadim V. Bichko, Ezhova Ev, Andrey Alexandrovich Ivashchenko, Oleg D. Mitkin, Alexandre V. Ivachtchenko
Publikováno v:
Pharmaceutical Chemistry Journal. 49:352-361
A focused library of heterocyclic compounds including a 2-aminomethyl-1H-benzimidazole (1 – 19), 2-aminomethylindole (20 – 83), benzofuran-2-ylmethylamine (84 – 92), or 2-piperazin-1-ylmethylbenzoxazole (93) fragment was screened for the abilit
Autor:
O. M. Korzinov, V. Yu. Vedenskii, Vadim V. Bichko, Andrey Alexandrovich Ivashchenko, Ya. A. Ivanenkov, Elena A. Bulanova, Oleg D. Mitkin, Ilya Okun, Alexandre Vasilievich Ivachtchenko, I. A. Leneva, V. M. Kisil, Pavel M. Yamanushkin
Publikováno v:
Pharmaceutical Chemistry Journal. 49:151-162
Novel substituted 5-hydroxy-2-aminomethyl-1H-indole-3-carboxylic acids and their derivatives were synthesized. The antiviral properties of these compounds were investigated in relation to bovine viral diarrhea virus (BVDV), hepatitis C virus (HCV), a