Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Andrey A. Zamyatnin, Jr."'
Autor:
Dmitry Kostyushev, Sergey Brezgin, Anastasiya Kostyusheva, Natalia Ponomareva, Ekaterina Bayurova, Natalia Zakirova, Alla Kondrashova, Irina Goptar, Anastasiya Nikiforova, Anna Sudina, Yurii Babin, Ilya Gordeychuk, Alexander Lukashev, Andrey A. Zamyatnin, Jr., Alexander Ivanov, Vladimir Chulanov
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 32, Iss , Pp 478-493 (2023)
APOBEC/AID cytidine deaminases play an important role in innate immunity and antiviral defenses and were shown to suppress hepatitis B virus (HBV) replication by deaminating and destroying the major form of HBV genome, covalently closed circular DNA
Externí odkaz:
https://doaj.org/article/7ce5cd1266eb4598acd572e3f56d611b
Autor:
Dmitry Kostyushev, Anastasiya Kostyusheva, Sergey Brezgin, Natalia Ponomareva, Natalia F. Zakirova, Aleksandra Egorshina, Dmitry V. Yanvarev, Ekaterina Bayurova, Anna Sudina, Irina Goptar, Anastasiya Nikiforova, Elena Dunaeva, Tatiana Lisitsa, Ivan Abramov, Anastasiia Frolova, Alexander Lukashev, Ilya Gordeychuk, Andrey A. Zamyatnin, Jr., Alexander Ivanov, Vladimir Chulanov
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 31, Iss , Pp 482-493 (2023)
CRISPR-Cas9 systems can directly target the hepatitis B virus (HBV) major genomic form, covalently closed circular DNA (cccDNA), for decay and demonstrate remarkable anti-HBV activity. Here, we demonstrate that CRISPR-Cas9-mediated inactivation of HB
Externí odkaz:
https://doaj.org/article/72f3a80274404491b3dc8295225eee9b
Autor:
Elena O. Kutumova, Ilya R. Akberdin, Vera S. Egorova, Ekaterina P. Kolesova, Alessandro Parodi, Vadim S. Pokrovsky, Andrey A. Zamyatnin, Jr, Fedor A. Kolpakov
Publikováno v:
Heliyon, Vol 10, Iss 10, Pp e30962- (2024)
The application of nanomedicine in the treatment of acute lung injury (ALI) has great potential for the development of new therapeutic strategies. To gain insight into the kinetics of nanocarrier distribution upon time-dependent changes in tissue per
Externí odkaz:
https://doaj.org/article/c4b46517d06b4b75b5cba7e56c05a898
Autor:
Natalia Ponomareva, Sergey Brezgin, Ivan Karandashov, Anastasiya Kostyusheva, Polina Demina, Olga Slatinskaya, Ekaterina Bayurova, Denis Silachev, Vadim S. Pokrovsky, Vladimir Gegechkori, Evgeny Khaydukov, Georgy Maksimov, Anastasia Frolova, Ilya Gordeychuk, Andrey A. Zamyatnin Jr., Vladimir Chulanov, Alessandro Parodi, Dmitry Kostyushev
Publikováno v:
Pharmaceutics, Vol 16, Iss 5, p 667 (2024)
Biological nanoparticles (NPs), such as extracellular vesicles (EVs), exosome-mimetic nanovesicles (EMNVs) and nanoghosts (NGs), are perspective non-viral delivery vehicles for all types of therapeutic cargo. Biological NPs are renowned for their exc
Externí odkaz:
https://doaj.org/article/ff61713c56ed4e8093ee57670e2cdf4b
Autor:
Andrei A. Deviatkin, Yulia A. Vakulenko, Ludmila V. Akhmadishina, Vadim V. Tarasov, Marina I. Beloukhova, Andrey A. Zamyatnin Jr., Alexander N. Lukashev
Publikováno v:
Biomedicines, Vol 8, Iss 1, p 9 (2020)
Rheumatoid arthritis (RA) is a systemic inflammatory joint disease affecting about 1% of the population worldwide. Current treatment approaches do not ensure a cure for every patient. Moreover, classical regimens are based on nontargeted systemic imm
Externí odkaz:
https://doaj.org/article/3d513383447f4fc3a1556423a5d440fe
Autor:
Andrey A. Zamyatnin Jr.
Publikováno v:
Current Pharmacogenomics and Personalized Medicine. 16:165-166
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 6552-6569 (2022)
Papain-like cysteine proteases are widely expressed enzymes that mostly regulate protein turnover in the acidic conditions of lysosomes. However, in the last twenty years, these proteases have been evidenced to exert specific functions within differe
Externí odkaz:
https://doaj.org/article/f3ec7f46add54acbbed3ffe6d904f648