Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Andrew j Bryant"'
Autor:
Alexandra a Aybar-Torres, Lennon A Saldarriaga, Ann T Pham, Amir M Emtiazjoo, Ashish K Sharma, Andrew j Bryant, Lei Jin
Publikováno v:
eLife, Vol 13 (2024)
The significance of STING1 gene in tissue inflammation and cancer immunotherapy has been increasingly recognized. Intriguingly, common human STING1 alleles R71H-G230A-R293Q (HAQ) and G230A-R293Q (AQ) are carried by ~60% of East Asians and ~40% of Afr
Externí odkaz:
https://doaj.org/article/f131d83056f845feb9ecbff5f78d6858
Autor:
Melody Walker, Helen Moore, Ali Ataya, Ann Pham, Paul A. Corris, Reinhard Laubenbacher, Andrew J. Bryant
Publikováno v:
Pulmonary Circulation, Vol 14, Iss 2, Pp n/a-n/a (2024)
Abstract Pulmonary hypertension (PH) is a severe medical condition with a number of treatment options, the majority of which are introduced without consideration of the underlying mechanisms driving it within an individual and thus a lack of tailored
Externí odkaz:
https://doaj.org/article/19747005a1a144959b14b8674e4095d4
Autor:
Aline C. Oliveira, Marianthi M. Karas, Matthew Alves, Jacky He, Annette D. de Kloet, Eric G. Krause, Elaine M. Richards, Andrew J. Bryant, Mohan K. Raizada
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
BackgroundPulmonary hypertension (PH), characterized by elevated pulmonary pressure and right heart failure, is a systemic disease involving inappropriate sympathetic activation and an impaired gut-brain-lung axis. Global overexpression of angiotensi
Externí odkaz:
https://doaj.org/article/da7756bc35f84345bd3d43a87f32c381
Autor:
Christopher A. Wolff, Miguel A. Gutierrez-Monreal, Lingsong Meng, Xiping Zhang, Lauren G. Douma, Hannah M. Costello, Collin M. Douglas, Elnaz Ebrahimi, Ann Pham, Aline C. Oliveira, Chunhua Fu, Amy Nguyen, Bryan R. Alava, Stuart J. Hesketh, Andrew R. Morris, Mehari M. Endale, G. Ryan Crislip, Kit-yan Cheng, Elizabeth A. Schroder, Brian P. Delisle, Andrew J. Bryant, Michelle L. Gumz, Zhiguang Huo, Andrew C. Liu, Karyn A. Esser
Publikováno v:
Cell Reports, Vol 42, Iss 1, Pp 111982- (2023)
Summary: Cellular circadian clocks direct a daily transcriptional program that supports homeostasis and resilience. Emerging evidence has demonstrated age-associated changes in circadian functions. To define age-dependent changes at the systems level
Externí odkaz:
https://doaj.org/article/2f18b4dcc2854c8b81ce1f23e09506dc
Autor:
Rudolf K. F. Oliveira, Peter S. Nyasulu, Adeel Ahmed Iqbal, Muhammad Hamdan Gul, Eloara V. M. Ferreira, John William Leclair, Zin Mar Htun, Luke S. Howard, Ana O. Mocumbi, Andrew J. Bryant, Jacques L. Tamuzi, Sergey Avdeev, Nicola Petrosillo, Ahmed Hassan, Ghazwan Butrous, Vinicio de Jesus Perez
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
COVID-19 infection primarily targets the lungs, which in severe cases progresses to cytokine storm, acute respiratory distress syndrome, multiorgan dysfunction, and shock. Survivors are now presenting evidence of cardiopulmonary sequelae such as pers
Externí odkaz:
https://doaj.org/article/f06121117d61446bb342dcc5a5fbbeb1
Autor:
Aline C. Oliveira, Tao Yang, Jing Li, Ravindra K. Sharma, Marianthi K. Karas, Andrew J. Bryant, Annette D. deKloet, Eric G. Krause, Bina Joe, Elaine M. Richards, Mohan K. Raizada
Publikováno v:
Pulmonary Circulation, Vol 12, Iss 1, Pp n/a-n/a (2022)
Abstract Recent evidence suggests pulmonary hypertension (PH), a disease of the pulmonary vasculature actually has multiorgan pathophysiology and perhaps etiology. Herein, we demonstrated that fecal matter transplantation from angiotensin‐convertin
Externí odkaz:
https://doaj.org/article/fa58f9f0edaf4278899313deb32170b5
Publikováno v:
Pulmonary Circulation, Vol 11 (2021)
For as long as nucleic acids have been utilized to vertically and horizontally transfer genetic material, living organisms have had to develop methods of recognizing cytosolic DNA as either pathogenic (microbial invasion) or physiologic (mitosis and
Externí odkaz:
https://doaj.org/article/a74dbab7911f4376a064e659e85e9c31
Autor:
Gene Ryan Crislip, Stephanie E. Wohlgemuth, Christopher A. Wolff, Miguel A. Gutierrez-Monreal, Collin M. Douglas, Elnaz Ebrahimi, Kit-Yan Cheng, Sarah H. Masten, Dominique Barral, Andrew J. Bryant, Karyn A. Esser, Michelle L. Gumz
Publikováno v:
Biomolecules, Vol 12, Iss 2, p 261 (2022)
BMAL1 is a core mammalian circadian clock transcription factor responsible for the regulation of the expression of thousands of genes. Previously, male skeletal-muscle-specific BMAL1-inducible-knockout (iMS-BMAL1 KO) mice have been described as a mod
Externí odkaz:
https://doaj.org/article/b478ab60a791410b8896f97c86721efd
Autor:
L. Cody Smith, Santiago Moreno, Lauren Robertson, Sarah Robinson, Kristal Gant, Andrew J. Bryant, Tara Sabo-Attwood
Publikováno v:
Respiratory Research, Vol 19, Iss 1, Pp 1-17 (2018)
Abstract Background Sex differences in idiopathic pulmonary fibrosis (IPF) suggest a protective role for estrogen (E2); however, mechanistic studies in animal models have produced mixed results. Reports using cell lines have investigated molecular in
Externí odkaz:
https://doaj.org/article/c8286471ef884e93b78159318f44b77f
Autor:
Andrew J. Bryant, Chunhua Fu, Yuanquing Lu, Mark L. Brantly, Borna Mehrad, Lyle L. Moldawer, Todd M. Brusko, Evan L. Brittain, James D. West, Eric D. Austin, Rizwan Hamid
Publikováno v:
Pulmonary Circulation, Vol 9 (2019)
Externí odkaz:
https://doaj.org/article/83b4b142c41c4478b870dcd0849de48a