Mammary epithelial-specific knockout of the ephrin-B2 gene leads to precocious epithelial cell death at lactation

Autor: Stéphanie Weiler, Andrew Ziemiecki, Anne-Catherine Andres, Ralf H. Adams, Valeria Rohrbach, Thekla Pulvirenti

Publikováno v: Development, Growth & Differentiation. 51:809-819

The family of Eph receptor tyrosine kinases and their membrane bound ligands, the ephrins, are involved in a wide variety of morphogenic processes during embryonic development and adult tissue homeostasis. Receptor-ligand interaction requires direct

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ea23723b6a1c4b6959c688823a944431
https://doi.org/10.1111/j.1440-169x.2009.01140.x

Activation of the receptor protein tyrosine kinase EphB4 in endometrial hyperplasia and endometrial carcinoma

Autor: L. Mazzucchelli, Andrew Ziemiecki, Evanthia Karamitopoulou, Anne-Catherine Andres, Gilles Berclaz, Valeria Rohrbach, E. Dreher

Publikováno v: Berclaz, G.; Karamitopoulou, E.; Mazzucchelli, L.; Rohrbach, V.; Dreher, E.; Ziemiecki, A.; Andres, A.-C. (2003). Activation of the receptor protein tyrosine kinase EphB4 in endometrial hyperplasia and endometrial carcinoma. Annals of oncology, 14(2), pp. 220-226. Oxford University Press 10.1093/annonc/mdg072

Background: Members of the Eph family of tyrosine kinases have been implicated in embryonic pattern formation and vascular development; however, little is known about their role in the adult organism. We have observed estrogen-dependent EphB4 express

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d904aec51346cb7ce51eec9abae11800
https://doi.org/10.1093/annonc/mdg072

Regulation and Function of the Cytokine-Inducible SH-2 Domain Proteins, CIS and SOCS3, in Mammary Epithelial Cells

Autor: Olivier Goupille, Andrew Ziemiecki, Wolfgang Doppler, Claudia Soratroi, Martin Tonko, Sibylle Tonko-Geymayer, Charles H. Streuli, Reinhard Kofler, Akihiko Yoshimura

Publikováno v: Molecular Endocrinology. 16:1680-1695

The cytokine-inducible src homology 2 (SH-2) proteins, CIS (cytokine inducible SH-2 domain protein) and SOCS3 (suppressor of cytokine signaling 3), are implicated in the negative regulation of prolactin (PRL) receptor-mediated activation of signal tr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e537bdcf9c1f64fa625135c1a284e89e
https://doi.org/10.1210/mend.16.7.0872

Pmg-1 and Pmg-2 constitute a novel family of KAP genes differentially expressed during skin and mammary gland development

Autor: Andrew Ziemiecki, Anne-Catherine Andres, Anne Range, Caro Lassing, Mathias Mueller, Franziska Kuhn, Thomas Hunziker

Publikováno v: Mechanisms of Development. 86(1-2):193-196

The epidermis, by invagination of the undifferentiated ectodermal cells, gives rise to several distinct structures including hair, sebaceous, eccrine sweat and mammary glands. We have recently isolated a novel gene, pmg-1, expressed in the pubertal m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfe90134275dd06ad56ed69fafb13332

Protein tyrosine kinase expression during the estrous cycle and carcinogenesis of the mammary gland

Autor: Martin Flueck, Anne-Catherine Andres, Andrew Ziemiecki, Valentin Djonov, Gisela Zuercher

Publikováno v: International Journal of Cancer. 63:288-296

The susceptibility of the mammary epithelium to neoplastic transformation is linked to the exposure to estrogen during the estrous cycle. The effects of the estrous cycle on the mouse mammary gland have been investigated by analyzing 3 H-thymidine in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d94b1763231794a1d9ecd16b5326fe92
https://doi.org/10.1002/ijc.2910630224