Zobrazeno 1 - 10
of 163
pro vyhledávání: '"Andrew Yates"'
Autor:
John Noone, Mary F. Rooney, Marilena Karavyraki, Andrew Yates, Saoirse E. O’Sullivan, Richard K. Porter
Publikováno v:
Pharmaceuticals, Vol 16, Iss 11, p 1580 (2023)
Cachexia syndrome, leading to reduced skeletal muscle and fat mass, is highly prevalent in cancer patients, resulting in further negative implications for these patients. To date, there is no approved therapy for cachexia syndrome. The objective of t
Externí odkaz:
https://doaj.org/article/66bc15e3d2ff4348838f1d516973fd4b
Autor:
Alessandra Ruggiero, Giuseppe Rubens Pascucci, Nicola Cotugno, Sara Domínguez-Rodríguez, Stefano Rinaldi, Alfredo Tagarro, Pablo Rojo, Caroline Foster, Alasdair Bamford, Anita De Rossi, Eleni Nastouli, Nigel Klein, Elena Morrocchi, Benoit Fatou, Kinga K. Smolen, Al Ozonoff, Michela Di Pastena, Katherine Luzuriaga, Hanno Steen, Carlo Giaquinto, Philip Goulder, Paolo Rossi, Ofer Levy, Savita Pahwa, Paolo Palma, the EPIICAL Consortium, Mark Cotton, Shaun Barnabas, Thanyawee Puthanakit, Louise Kuhn, Andrew Yates, Avy Violari, Kennedy Otwombe, Paula Vaz, Maria Grazia Lain, Tacilta Nampossa, Denise Naniche, Sheila Fernandez-Luis, Elisa Lopez, Holly Peay, Moira Spyer, Vincent Calvez, Anne-Genevieve Marcelin, Maria Angeles Munoz, Annalisa Dalzini, Raffaella Petrara, Kathleen Gartner, Lesley De Armas, Pahwa Rajendra, Suresh Pallikkuth, Deborah Persaud, Nicolas Chomont, Mathias Lichterfeld, Silvia Faggion, Daniel Gomez Pena, Andrea Oletto, Alessandra Nardone, Paola Zangari, Silvia Di Cesare, Chiara Medri, Olga Kolesova, Carla Paganin, William James, Inger Lindfors - Rossi, Shrabon Samiur Hassan, Francesca Mazzetto, Hellen Akisinku, Musakanya Chingandu, Francesca Rocchi, Ilaria Pepponi, Rob J. De Boer, Juliane Schroter, Viviana Giannuzzi, Sinead Morris
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundDespite a successful antiretroviral therapy (ART), adolescents living with perinatally acquired HIV (PHIV) experience signs of B-cell hyperactivation with expansion of ‘namely’ atypical B-cell phenotypes, including double negative (CD27
Externí odkaz:
https://doaj.org/article/4c3438cc6e094cf89b7fa756b480c8ba
Autor:
Jeff E Mold, Pedro Réu, Axel Olin, Samuel Bernard, Jakob Michaëlsson, Sanket Rane, Andrew Yates, Azadeh Khosravi, Mehran Salehpour, Göran Possnert, Petter Brodin, Jonas Frisén
Publikováno v:
PLoS Biology, Vol 17, Iss 10, p e3000383 (2019)
Thymic involution and proliferation of naive T cells both contribute to shaping the naive T-cell repertoire as humans age, but a clear understanding of the roles of each throughout a human life span has been difficult to determine. By measuring nucle
Externí odkaz:
https://doaj.org/article/7967f405036848668c522851a8edc2de
Publikováno v:
Bio-Protocol, Vol 7, Iss 24 (2017)
This protocol was developed to increase the richness of information available from in vivo T cell proliferation studies. DNA labelling techniques such as BrdU incorporation allow precise control of label administration and withdrawal, so that the div
Externí odkaz:
https://doaj.org/article/2fc7caee8a284a78ad6049870c58e982
Publikováno v:
Bio-Protocol, Vol 7, Iss 24 (2017)
This protocol was developed to generate chimeric mice in which T lymphocytes could be stratified by age on the basis of congenic marker expression. The conditioning drug busulfan is used to ablate host haematopoietic stem cells while leaving the peri
Externí odkaz:
https://doaj.org/article/ff0ad5f9205f4181955468758a60d174
Publikováno v:
PLoS Computational Biology, Vol 10, Iss 9, p e1003805 (2014)
The rate at which a cytotoxic T lymphocyte (CTL) can survey for infected cells is a key ingredient of models of vertebrate immune responses to intracellular pathogens. Estimates have been obtained using in vivo cytotoxicity assays in which peptide-pu
Externí odkaz:
https://doaj.org/article/fea4525fc52f47e7bbfa7d258ead18c5
Publikováno v:
PLoS Medicine, Vol 5, Iss 1 (2008)
Externí odkaz:
https://doaj.org/article/922e37b871534eda95ea0462b1b09e37
Publikováno v:
PLoS ONE, Vol 2, Iss 12, p e1301 (2007)
Recent experimental advances have allowed the estimation of the in vivo rates of killing of infected target cells by cytotoxic T lymphocytes (CTL). We present several refinements to a method applied previously to quantify killing of targets in the sp
Externí odkaz:
https://doaj.org/article/8be9c6f0647e42c4af243ff5c26fc978
Publikováno v:
PLoS Medicine, Vol 4, Iss 5, p e177 (2007)
The asymptomatic phase of HIV infection is characterised by a slow decline of peripheral blood CD4(+) T cells. Why this decline is slow is not understood. One potential explanation is that the low average rate of homeostatic proliferation or immune a
Externí odkaz:
https://doaj.org/article/67297eb9044c4df3808175be654be2ed
Autor:
CANJIA LI1 canjiali@mpi-inf.mpg.de, ANDREW YATES2 ayates@mpi-inf.mpg.de, SEAN MACAVANEY3 sean.macavaney@glasgow.ac.uk, BEN HE4 benhe@ucas.ac.cn, YINGFEI SUN4 yfsun@ucas.ac.cn
Publikováno v:
ACM Transactions on Information Systems. Mar2024, Vol. 42 Issue 2, p1-26. 26p.