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pro vyhledávání: '"Andrew Widjaja"'
Publikováno v:
Mech Ageing Dev
Stem cell aging contributes to aging-associated tissue degeneration and dysfunction. Recent studies reveal a mitochondrial metabolic checkpoint that regulates stem cell quiescence and maintenance, and dysregulation of the checkpoint leads to function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b33a27928e2102d4e3ce9f0ab5de8042
https://europepmc.org/articles/PMC7375904/
https://europepmc.org/articles/PMC7375904/
Publikováno v:
Aging Cell
Summary The mitochondrial unfolded protein response (UPR mt), a cellular protective program that ensures proteostasis in the mitochondria, has recently emerged as a regulatory mechanism for adult stem cell maintenance that is conserved across tissues