Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Andrew Warnock"'
Autor:
Larissa K. Dill, Natalie A. Sims, Ali Shad, Chidozie Anyaegbu, Andrew Warnock, Yilin Mao, Melinda Fitzgerald, Bridgette D. Semple
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract While it is well-established that bone responds dynamically to mechanical loading, the effects of mild traumatic brain injury (mTBI) on cranial bone composition are unclear. We hypothesized that repeated mTBI (rmTBI) would change the microst
Externí odkaz:
https://doaj.org/article/39362a8ea7ce4d37b70c770ad3507d55
Autor:
Lillian M. Toomey, Melissa Papini, Brittney Lins, Alexander J. Wright, Andrew Warnock, Terence McGonigle, Sarah C. Hellewell, Carole A. Bartlett, Chidozie Anyaegbu, Melinda Fitzgerald
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract Cuprizone is a copper-chelating agent that induces pathology similar to that within some multiple sclerosis (MS) lesions. The reliability and reproducibility of cuprizone for inducing demyelinating disease pathology depends on the animals in
Externí odkaz:
https://doaj.org/article/580b3adbc43c41d781115c06f9481e95
Autor:
Bailey Hiles-Murison, Andrew P. Lavender, Mark J. Hackett, Joshua J. Armstrong, Michael Nesbit, Samuel Rawlings, Terrence McGonigle, Andrew Warnock, Virginie Lam, John C. L. Mamo, Melinda Fitzgerald, Ryu Takechi
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Repeated sub-concussive impact (e.g. soccer ball heading), a significantly lighter form of mild traumatic brain injury, is increasingly suggested to cumulatively alter brain structure and compromise neurobehavioural function in the long-term
Externí odkaz:
https://doaj.org/article/cf82d2fd2ba345389667629116ebde2a
Autor:
Brittney R. Lins, Chidozie C. Anyaegbu, Terence McGonigle, Sarah C. Hellewell, Parth Patel, Harry Reagan, Cara Rooke-Wiesner, Andrew Warnock, Michael Archer, Jan M. Hemmi, Carole Bartlett, Melinda Fitzgerald
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 3343 (2023)
Adolescence is a critical period of postnatal development characterized by social, emotional, and cognitive changes. These changes are increasingly understood to depend on white matter development. White matter is highly vulnerable to the effects of
Externí odkaz:
https://doaj.org/article/42584b8958d142399ba2d08ef2299d28
Autor:
Lillian M. Toomey, Melissa G. Papini, Thomas O. Clarke, Alexander J. Wright, Eleanor Denham, Andrew Warnock, Terry McGonigle, Carole A. Bartlett, Melinda Fitzgerald, Chidozie C. Anyaegbu
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 3463 (2023)
Optic nerve injury causes secondary degeneration, a sequela that spreads damage from the primary injury to adjacent tissue, through mechanisms such as oxidative stress, apoptosis, and blood-brain barrier (BBB) dysfunction. Oligodendrocyte precursor c
Externí odkaz:
https://doaj.org/article/60ef5f1a63904b4b834c8b560122c178
Repeated Long-Term Sub-concussion Impacts Induce Motor Dysfunction in Rats: A Potential Rodent Model
Autor:
Andrew P. Lavender, Samuel Rawlings, Andrew Warnock, Terry McGonigle, Bailey Hiles-Murison, Michael Nesbit, Virginie Lam, Mark J. Hackett, Melinda Fitzgerald, Ryusuke Takechi
Publikováno v:
Frontiers in Neurology, Vol 11 (2020)
Whilst detrimental effects of repeated sub-concussive impacts on neurophysiological and behavioral function are increasingly reported, the underlying mechanisms are largely unknown. Here, we report that repeated sub-concussion with a light weight dro
Externí odkaz:
https://doaj.org/article/b7838249bcf247da843c39e3ec6c428e
Autor:
C. Bartlett, Melinda Fitzgerald, Sarah C Hellewell, Alexander J Wright, Brittney R. Lins, Terence McGonigle, Chidozie C. Anyaegbu, Melissa Papini, Lillian M. Toomey, Andrew Warnock
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Scientific Reports
Scientific Reports
Cuprizone is a copper-chelating agent that induces pathology similar to that within some multiple sclerosis (MS) lesions. The reliability and reproducibility of cuprizone for inducing demyelinating disease pathology depends on the animals ingesting c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2d706e44bd5329c4bc3f0614191de9a
https://doaj.org/article/580b3adbc43c41d781115c06f9481e95
https://doaj.org/article/580b3adbc43c41d781115c06f9481e95
Autor:
Michael Nesbit, John C.L. Mamo, Melinda Fitzgerald, Bailey Hiles-Murison, Mark J. Hackett, Terrence McGonigle, Ryu Takechi, Samuel Rawlings, Virginie Lam, Andrew Warnock, Joshua J. Armstrong, Andrew P. Lavender
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports
Scientific Reports
Repeated sub-concussive impact (e.g. soccer ball heading), a significantly lighter form of mild traumatic brain injury, is increasingly suggested to cumulatively alter brain structure and compromise neurobehavioural function in the long-term. However
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6db3cc83acd84605aff5b8cd12062b91
https://doaj.org/article/cf82d2fd2ba345389667629116ebde2a
https://doaj.org/article/cf82d2fd2ba345389667629116ebde2a
Autor:
Chidozie C. Anyaegbu, Yerim Won, Melinda Fitzgerald, Lillian M. Toomey, Alexander J Wright, Andrew Warnock, Katherine Fisher
Publikováno v:
Journal of Neurotrauma. 37:739-769
Traumatic brain injury (TBI) and spinal cord injury (SCI) present a significant contribution to the global disease burden. White matter tracts are susceptible to both the physical forces of trauma and cascades of pathological secondary degeneration.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac90f3545d2685102c62de372967075c
https://doi.org/10.1089/neu.2019.6890
https://doi.org/10.1089/neu.2019.6890
Autor:
Alexander Gough, Melinda Fitzgerald, Andrew Warnock, Gopana Gopalasingam, Carole A. Bartlett, Terence McGonigle, Abbey Ford, Maimuna Majimbi, Lillian M. Toomey
Publikováno v:
Multiple sclerosis and related disorders. 34
Background Multiple sclerosis (MS) has been shown to feature oxidative damage, which can be modelled using the cuprizone model of demyelinating disease. Oxidative damage can occur as a result of excessive influx of calcium ions (Ca2+) and oligodendro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::580c346dcd50b654c0696d098e249807
https://pubmed.ncbi.nlm.nih.gov/31202958
https://pubmed.ncbi.nlm.nih.gov/31202958