Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Andrew W. Shyjan"'
Autor:
Andrew W. Shyjan, Deborah L. Nagle, Jing Shao, Karen J. Moore, Barry J. Dussault, John J. Hunter, Elizabeth A. Woolf, John S. Smutko, Lisa Holmgren
Publikováno v:
Genomics. 54:116-123
We recently described a novel gene, melastatin, whose expression is inversely correlated with melanoma aggressiveness. Chromosomal localization of this gene places it on mouse chromosome 7 and in the 15q13–q14 region of the human genome. Although e
Autor:
Nanhua Deng, Andrew W. Shyjan, Marlene Dembski, Stephen J Ellis, Ruth E. Gimeno, Francois Iris, Xun Weng, Louis A. Tartaglia, Carlos J. Gimeno, Elizabeth A. Woolf
Publikováno v:
Diabetes. 46:900-906
We have identified a novel cDNA encoding a protein highly homologous to the mammalian brown fat uncoupling protein (UCP). Unlike the known UCP, which is expressed specifically in brown adipose tissue, the UCP homolog (UCPH) mRNA is expressed in a var
Publikováno v:
Genomics. 11:435-442
We have cloned and characterized the mouse Na,K-ATPase beta 2 subunit gene (Atp1b2). The gene spans approximately 7 kb and is split into seven exons. The transcription initiation site has been mapped and consensus TATA and putative CAAT sequences hav
Publikováno v:
Journal of Histochemistry & Cytochemistry. 39:507-517
Na,K-ATPase plays a central role in the visual sensitivity of photoreceptors by driving the dark current of vision. The alpha 3 and beta 2 isoforms of Na,K-ATPase were previously shown to be the major alpha and beta subunit mRNAs expressed in photore
Publikováno v:
Journal of Biological Chemistry. 265:5166-5169
We have used a cloned fusion protein as antigen to generate an antiserum specific for the rat Na,K-ATPase beta 2 subunit. Utilizing this antiserum, we analyzed some of the structural features and tissue distribution of the beta 2 subunit. Treatment o
Autor:
William L. Perry, Anne H. Dantzig, Andrea Lesoon, Shengfang Jin, Mark Rolfe, Kathryn A. O'Brien, Michelle Tighe, Victoria L. Peek, Venkatesh Krishnan, Mark Williamson, Benjamin C. Yaden, Andrew W. Shyjan, William W. Chin, Philip W. Iversen, Robert E. Moore, Robert L. Shepard, Janardhan Sampath
Publikováno v:
Cancer research. 65(15)
The splicing factor SPF45 (RBM17) is frequently overexpressed in many solid tumors, and stable expression in HeLa cells confers resistance to doxorubicin and vincristine. In this study, we characterized stable transfectants of A2780 ovarian carcinoma
Publikováno v:
The Journal of biological chemistry. 270(49)
Rtg1p is a basic helix-loop-helix transcription factor in the yeast Saccharomyces cerevisiae that is required for basal and regulated expression of CIT2, the gene encoding a peroxisomal isoform of citrate synthase. In respiratory incompetent rho degr
Publikováno v:
Brain research. Molecular brain research. 21(3-4)
We have analyzed the expression pattern of Na,K-ATPase alpha and beta subunit isoforms within the rodent and primate central nervous system. Membrane fractions prepared from rat cerebral cortical type-1 astrocytes and rat cerebellar granule and hippo
Autor:
Andrew W. Shyjan, Robert Levenson
Publikováno v:
Biochemistry. 28(11)
We have developed a panel of antibodies specific for the alpha 1, alpha 2, alpha 3, and beta subunits of the rat Na,K-ATPase. TrpE-alpha subunit isoform fusion proteins were used to generate three antisera, each of which reacted specifically with a d