Zobrazeno 1 - 10
of 253
pro vyhledávání: '"Andrew W. Horne"'
Autor:
Christopher J. Hill, Marie M. Phelan, Philip J. Dutton, Paula Busuulwa, Alison Maclean, Andrew S. Davison, Josephine A. Drury, Nicola Tempest, Andrew W. Horne, Eva Caamaño Gutiérrez, Dharani K. Hapangama
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract A significant number of pregnancies are lost in the first trimester and 1–2% are ectopic pregnancies (EPs). Early pregnancy loss in general can cause significant morbidity with bleeding or infection, while EPs are the leading cause of mate
Externí odkaz:
https://doaj.org/article/1c884d8295224599943b76824990b61d
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-4 (2023)
Endometriosis is an incurable, under-diagnosed, systemic inflammatory disease affecting millions world-wide. Common symptoms include life-impacting pain, gastrointestinal/urinary symptoms, excessive fatigue, and infertility. Global public health poli
Externí odkaz:
https://doaj.org/article/c18a0ab882e94651a2cb9369d34bc541
Autor:
Sally Mortlock, Sahar Houshdaran, Idit Kosti, Nilufer Rahmioglu, Camran Nezhat, Allison F. Vitonis, Shan V. Andrews, Parker Grosjean, Manish Paranjpe, Andrew W. Horne, Alison Jacoby, Jeannette Lager, Jessica Opoku-Anane, Kim Chi Vo, Evelina Manvelyan, Sushmita Sen, Zhanna Ghukasyan, Frances Collins, Xavier Santamaria, Philippa Saunders, Kord Kober, Allan F. McRae, Kathryn L. Terry, Júlia Vallvé-Juanico, Christian Becker, Peter A. W. Rogers, Juan C. Irwin, Krina Zondervan, Grant W. Montgomery, Stacey Missmer, Marina Sirota, Linda Giudice
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-17 (2023)
Abstract Endometriosis is a leading cause of pain and infertility affecting millions of women globally. Herein, we characterize variation in DNA methylation (DNAm) and its association with menstrual cycle phase, endometriosis, and genetic variants th
Externí odkaz:
https://doaj.org/article/f61d2545020c46a2baff0d24cc8d121a
Autor:
Scott C. Mackenzie, Jacqueline Stephen, Linda Williams, Jane Daniels, John Norrie, Christian M. Becker, Dominic Byrne, Ying Cheong, T. Justin Clark, Kevin G. Cooper, Emma Cox, Ann M. Doust, Priscilla Fernandez, Jeremy Hawe, Tom Holland, Lone Hummelshoj, Louise J. Jackson, Kathleen King, Abha Maheshwari, Dan C. Martin, Lauren Sutherland, Jim Thornton, Katy Vincent, Sanjay Vyas, Andrew W. Horne, Lucy H. R. Whitaker
Publikováno v:
Trials, Vol 24, Iss 1, Pp 1-15 (2023)
Abstract Background Endometriosis affects 190 million women and those assigned female at birth worldwide. For some, it is associated with debilitating chronic pelvic pain. Diagnosis of endometriosis is often achieved through diagnostic laparoscopy. H
Externí odkaz:
https://doaj.org/article/e378d0205550443986bcd63318413961
Autor:
Dora B. Balogh, Gernot Hudelist, Dmitrijs Bļizņuks, Jayanth Raghothama, Christian M. Becker, Roman Horace, Harald Krentel, Andrew W. Horne, Nicolas Bourdel, Gabriella Marki, Carla Tomassetti, Ulrik Bak Kirk, Nandor Acs, Attila Bokor
Publikováno v:
PLoS ONE, Vol 19, Iss 5 (2024)
Externí odkaz:
https://doaj.org/article/dfca6af5b09b4e00bd5d2e839c5397c2
Autor:
Lysia Demetriou, Michal Krassowski, Pedro Abreu Mendes, Kurtis Garbutt, Allison F. Vitonis, Elizabeth Wilkins, Lydia Coxon, Lars Arendt-Nielsen, Qasim Aziz, Judy Birch, Andrew W. Horne, Anja Hoffman, Lone Hummelshoj, Claire E. Lunde, Jane Meijlink, Danielle Perro, Nilufer Rahmioglu, Kathryn L. Terry, Esther Pogatzki-Zahn, Christine B. Sieberg, Rolf-Detlef Treede, Christian M. Becker, Francisco Cruz, Stacey A. Missmer, Krina T. Zondervan, Jens Nagel, Katy Vincent
Publikováno v:
Frontiers in Reproductive Health, Vol 5 (2023)
IntroductionChronic pelvic pain (CPP) is a common condition affecting up to 26.6% of women, with many suffering for several years before diagnosis and/or treatment. Its clinical presentation is varied and there are frequently comorbid conditions both
Externí odkaz:
https://doaj.org/article/f24c4c3f6d2e4bcfb363810047da7318
Autor:
Lucy H. R. Whitaker, Ann Doust, Jacqueline Stephen, John Norrie, Kevin Cooper, Jane Daniels, Lone Hummelshoj, Emma Cox, Laura Beatty, Patrick Chien, Mayank Madhra, Katy Vincent, Andrew W. Horne
Publikováno v:
Pilot and Feasibility Studies, Vol 7, Iss 1, Pp 1-8 (2021)
Abstract Background Endometriosis (where endometrial-like tissue is found outside the uterus) affects ~ 176 million women worldwide and can lead to debilitating pelvic pain. Three subtypes of endometriosis exist, with ~ 80% of women having superficia
Externí odkaz:
https://doaj.org/article/ac96e3965eac4e2897c80fe3ea856735
Publikováno v:
Frontiers in Reproductive Health, Vol 3 (2021)
Endometriosis is a common gynecological condition characterized by the growth of endometrial-like tissue outside of the uterus which may cause symptoms such as chronic pelvic pain or subfertility. Several surgical and medical therapies are available
Externí odkaz:
https://doaj.org/article/9667a3cebbf04a80bf223fb76d71b541
Autor:
Ashley Dorning, Priya Dhami, Kavita Panir, Chloe Hogg, Emma Park, Gregory D. Ferguson, Diane Hargrove, James Karras, Andrew W. Horne, Erin Greaves
Publikováno v:
Disease Models & Mechanisms, Vol 14, Iss 8 (2021)
Our understanding of the aetiology and pathophysiology of endometriosis remains limited. Disease modelling in the field is problematic as many versions of induced mouse models of endometriosis exist. We integrated bioluminescent imaging of ‘lesions
Externí odkaz:
https://doaj.org/article/5054755a64ad4c8a80cbeb745bf0a821
Autor:
James May, Colin Duncan, Ben Mol, Siladitya Bhattacharya, Jane Daniels, Lee Middleton, Catherine Hewitt, Arri Coomarasamy, Davor Jurkovic, Tom Bourne, Cecilia Bottomley, Alexandra Peace-Gadsby, Ann Doust, Stephen Tong, Andrew W. Horne
Publikováno v:
Trials, Vol 19, Iss 1, Pp 1-8 (2018)
Abstract Background Tubal ectopic pregnancy (tEP) is the most common life-threatening condition in gynaecology. Treatment options include surgery and medical management. Stable women with tEPs with pre-treatment serum human chorionic gonadotrophin (h
Externí odkaz:
https://doaj.org/article/c4eebc52d7d64b2abe68d2c03dc5378e