Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Andrew W. Duncan"'
Autor:
Jihong Ma, Xinping Tan, Yongkook Kwon, Evan R. Delgado, Arman Zarnegar, Marie C. DeFrances, Andrew W. Duncan, Reza Zarnegar
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 2, Pp 565-582 (2022)
Background & Aims: Nonalcoholic fatty liver disease is a frequent cause of hepatic dysfunction and is now a global epidemic. This ailment can progress to an advanced form called nonalcoholic steatohepatitis (NASH) and end-stage liver disease. Current
Externí odkaz:
https://doaj.org/article/7e58c9b02e0346ed9b58c9790204be6a
Autor:
Huabo Wang, Jie Lu, Frances Alencastro, Alexander Roberts, Julia Fiedor, Patrick Carroll, Robert N. Eisenman, Sarangarajan Ranganathan, Michael Torbenson, Andrew W. Duncan, Edward V. Prochownik
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 6, Pp 1785-1804 (2022)
Background & Aims: The c-Myc (Myc) Basic helix-loop-helix leucine zipper (bHLH-ZIP) transcription factor is deregulated in most cancers. In association with Max, Myc controls target genes that supervise metabolism, ribosome biogenesis, translation, a
Externí odkaz:
https://doaj.org/article/f512386ec4624aa09ce95376ee392615
Autor:
Kazuki Takeishi, Alexandra Collin de l’Hortet, Yang Wang, Kan Handa, Jorge Guzman-Lepe, Kentaro Matsubara, Kazutoyo Morita, Sae Jang, Nils Haep, Rodrigo M. Florentino, Fangchao Yuan, Ken Fukumitsu, Kimimasa Tobita, Wendell Sun, Jonathan Franks, Evan R. Delgado, Erik M. Shapiro, Nicolas A. Fraunhoffer, Andrew W. Duncan, Hiroshi Yagi, Tomoji Mashimo, Ira J. Fox, Alejandro Soto-Gutierrez
Publikováno v:
Cell Reports, Vol 31, Iss 9, Pp - (2020)
Summary: The availability of an autologous transplantable auxiliary liver would dramatically affect the treatment of liver disease. Assembly and function in vivo of a bioengineered human liver derived from induced pluripotent stem cells (iPSCs) has n
Externí odkaz:
https://doaj.org/article/2669d2ed58534d89a4a0eccc2bf0473f
Autor:
Sierra R. Wilson, Andrew W. Duncan
Publikováno v:
Gastroenterology. 162:46-48
Publikováno v:
Semin Liver Dis
Hepatocytes are the primary functional cells of the liver that perform essential roles in homeostasis, regeneration, and injury. Most mammalian somatic cells are diploid and contain pairs of each chromosome, but there are also polyploid cells contain
Autor:
Nairita Roy, Frances Alencastro, Bayley A. Roseman, Sierra R. Wilson, Evan R. Delgado, Meredith C. May, Bharat Bhushan, Fiona M. Bello, Michael J. Jurczak, Sruti Shiva, Joseph Locker, Sebastien Gingras, Andrew W. Duncan
Publikováno v:
The American journal of pathology. 192(9)
Nonalcoholic fatty liver disease (NAFLD) is an epidemic affecting 30% of the US population. It is characterized by insulin resistance, and by defective lipid metabolism and mitochondrial dysfunction in the liver. SLC25A34 is a major repressive target
Autor:
Andrew W. Duncan, John Stoops, Bharat Bhushan, George K. Michalopoulos, Jianhua Luo, Anne Orr, Yanping Yu, William C. Bowen, Wendy M. Mars, Yuhua Xue, Junyan Tao
Publikováno v:
Am J Pathol
The activation of CD81 [the portal of entry of hepatitis C virus (HCV)] by agonistic antibody results in phosphorylation of Ezrin via Syk kinase and is associated with inactivation of the Hippo pathway and increase in yes-associated protein (Yap1). T
Autor:
Bryan N. Brown, Frances Alencastro, Samuel T. LoPresti, Nairita Roy, Satdarshan P.S. Monga, Andrew W. Duncan, Elizabeth C. Stahl, Patrick D. Wilkinson, Evan R. Delgado, Clint D. Skillen, Martin J. Haschak
Publikováno v:
Am J Pathol
Aging is associated with inflammation and metabolic syndrome, which manifests in the liver as nonalcoholic fatty liver disease (NAFLD). NAFLD can range in severity from steatosis to fibrotic steatohepatitis and is a major cause of hepatic morbidity.
Publikováno v:
The Liver
Autor:
David N. Boone, Yuanyuan Chen, Kenneth J. DeHaan, Sheila Pratt, Tobias A. Baker, Steve Evans, Malihe Alikhani, Steffi Oesterreich, Jennifer M. Atkinson, Andrew W. Duncan, Deborah L. Galson, Greg M. Delgoffe, Tullia C. Bruno, Solomon Livshits, Richard D. Boyce, Joseph C. Ayoob
Publikováno v:
J STEM Outreach
The University of Pittsburgh Medical Center Hillman Cancer Center Academy (Hillman Academy) has the primary goal of reaching high school students from underrepresented and disadvantaged backgrounds and guiding them through a cutting-edge research and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa0b1ee826dad0b18fda472b94a26cbd
https://europepmc.org/articles/PMC9997544/
https://europepmc.org/articles/PMC9997544/