Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Andrew W Lindsley"'
Autor:
Sarah J. Potter, Li Zhang, Michael Kotliar, Yuehong Wu, Caitlin Schafer, Kurtis Stefan, Leandros Boukas, Dima Qu’d, Olaf Bodamer, Brittany N. Simpson, Artem Barski, Andrew W. Lindsley, Hans T. Bjornsson
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Individuals with Kabuki syndrome present with immunodeficiency; however, how pathogenic variants in the gene encoding the histone-modifying enzyme lysine methyltransferase 2D (KMT2D) lead to immune alterations remain poorly understood. Following up o
Externí odkaz:
https://doaj.org/article/cf9678b7fb124e57af5f1be2328c292d
Autor:
NJIRA L LUGOGO, PRAVEEN AKUTHOTA, SAMEER K MATHUR, AUTUMN BURNETTE, KAHARU SUMINO, NIKITA ARYA, NICOLE CLARKE, ANDREW W LINDSLEY, JEAN-PIERRE LLANOS ACKERT, CHRISTOPHER AMBROSE, WILLIAM COOK, BENJAMIN EMMANUEL
Publikováno v:
Chest. 162:A37-A40
Autor:
Jonathan Corren, Christopher S. Ambrose, Janet M. Griffiths, Åsa Hellqvist, Andrew W. Lindsley, Jean‐Pierre Llanos, Gene Colice, Andrew Menzies‐Gow
Publikováno v:
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical ImmunologyREFERENCES.
Allergic asthma is the most common phenotype among patients with severe asthma. In the phase 3 NAVIGATOR study (NCT03347279), tezepelumab significantly reduced the annualized asthma exacerbation rate (AAER) versus placebo in patients with severe, unc
Autor:
Sarah J Potter, Li Zhang, Michael Kotliar, Yuehong Wu, Caitlin Schafer, Kurtis Stefan, Leandros Boukas, Dima Qu’d, Olaf Bodamer, Brittany N Simpson, Artem Barski, Andrew W Lindsley, Hans T Bjornsson
ObjectiveThere is a clinical need to understand how dysregulated thymocyte development, caused by pathogenic variants in the gene encoding the histone-modifying enzyme, lysine methyltransferase 2D (KMT2D), contributes to immune dysfunction, including
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29c23032151b736380beb719e9be9406
https://doi.org/10.1101/2022.10.04.510662
https://doi.org/10.1101/2022.10.04.510662
Autor:
MARIO CASTRO, WILLIAM COOK, CHRISTOPHER AMBROSE, ANDREW W LINDSLEY, GILLIAN HUNTER, NEIL MARTIN, SANDHIA PONNARAMBIL
Publikováno v:
Chest. 162:A35-A36
Autor:
Nat Nasomyont, Andrew W. Lindsley, Derek E Neilson, Cassandra C Brady, Amal Assa'ad, D. Brian Dawson, Meilan M. Rutter
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 104:4051-4057
Context Deficient anterior pituitary with variable immune deficiency (DAVID) syndrome is a recently described, rare disorder characterized by anterior pituitary hormone deficiencies and common variable immunodeficiency associated with NFKB2 mutations
Autor:
Norio Niikawa, C. T. R. M. Stumpel, Giuseppe Merla, Nobuhiko Okamoto, Albert E. Chudley, Siddharth Banka, Andrew W. Lindsley, Jaqueline Harris, Olaf Bodamer, Hiroshi Kawame, Margaret P. Adam, Noriko Miyake, Hans T. Bjornsson, Brendan C. Lanpher
Publikováno v:
Journal of Medical Genetics, 56(2), 89-95. BMJ Publishing Group
Kabuki Syndrome Medical Advisory Board 2018, ' Kabuki syndrome : international consensus diagnostic criteria ', Journal of Medical Genetics . https://doi.org/10.1136/jmedgenet-2018-105625
Kabuki Syndrome Medical Advisory Board 2018, ' Kabuki syndrome : international consensus diagnostic criteria ', Journal of Medical Genetics . https://doi.org/10.1136/jmedgenet-2018-105625
BackgroundKabuki syndrome (KS) is a clinically recognisable syndrome in which 70% of patients have a pathogenic variant in KMT2D or KDM6A. Understanding the function of these genes opens the door to targeted therapies. The purpose of this report is t
Autor:
Rebecca A. Marsh, Andrew W. Lindsley
Publikováno v:
Primary and Secondary Immunodeficiency ISBN: 9783030571566
Several genetic syndromes that feature prominent non-immune system problems can be associated with immunodeficiency. These disorders are sometimes collectively referred to as “syndromic primary immunodeficiencies” (PIDs) or “syndromic immunodef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c50ea7106427fbda4fb0a42aec6aa4c4
https://doi.org/10.1007/978-3-030-57157-3_11
https://doi.org/10.1007/978-3-030-57157-3_11
Autor:
Richard Strait, Jaclyn W. McAlees, Christopher G. McKnight, Theresa Baker, Xue Zhang, Lauren K. Houshel, Melinda Butsch Kovacic, Ian P. Lewkowich, Jocelyn Biagini, Andrew W. Lindsley
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e7a5950b483f792add0754a28090df8
https://doi.org/10.22541/au.160579640.03001605/v1
https://doi.org/10.22541/au.160579640.03001605/v1
Publikováno v:
Journal of Allergy and Clinical Immunology
The Journal of Allergy and Clinical Immunology
The Journal of Allergy and Clinical Immunology
Eosinophils are circulating and tissue-resident leukocytes that have potent proinflammatory effects in a number of diseases. Recently, eosinophils have been shown to have various other functions, including immunoregulation and antiviral activity. Eos