Zobrazeno 1 - 10
of 254
pro vyhledávání: '"Andrew W, Horne"'
Autor:
Lydia Coxon, Maryam Amer, Jane Daniels, Ann M. Doust, Scott C. Mackenzie, Andrew W. Horne, Katy Vincent
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
IntroductionChronic pelvic pain affects up to 24% of women worldwide and for up to 55% of these there is no associated pathology. Despite this there are no established treatments in this cohort. This is a secondary analysis of a randomised-controlled
Externí odkaz:
https://doaj.org/article/1d707212413646b6abd32e63febdfbfc
Publikováno v:
Reproduction and Fertility, Vol 5, Iss 2, Pp 1-20 (2024)
Endometriosis is a chronic inflammatory condition affecting one in ten women and those assigned female at birth, defined by the presence of endometrial-like tissue outside the uterus. It is commonly associated with pain, infertility, and mood disorde
Externí odkaz:
https://doaj.org/article/2e841c33c6094505b9b42380a215444f
Autor:
Christopher J. Hill, Marie M. Phelan, Philip J. Dutton, Paula Busuulwa, Alison Maclean, Andrew S. Davison, Josephine A. Drury, Nicola Tempest, Andrew W. Horne, Eva Caamaño Gutiérrez, Dharani K. Hapangama
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract A significant number of pregnancies are lost in the first trimester and 1–2% are ectopic pregnancies (EPs). Early pregnancy loss in general can cause significant morbidity with bleeding or infection, while EPs are the leading cause of mate
Externí odkaz:
https://doaj.org/article/1c884d8295224599943b76824990b61d
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-4 (2023)
Endometriosis is an incurable, under-diagnosed, systemic inflammatory disease affecting millions world-wide. Common symptoms include life-impacting pain, gastrointestinal/urinary symptoms, excessive fatigue, and infertility. Global public health poli
Externí odkaz:
https://doaj.org/article/c18a0ab882e94651a2cb9369d34bc541
Autor:
Sally Mortlock, Sahar Houshdaran, Idit Kosti, Nilufer Rahmioglu, Camran Nezhat, Allison F. Vitonis, Shan V. Andrews, Parker Grosjean, Manish Paranjpe, Andrew W. Horne, Alison Jacoby, Jeannette Lager, Jessica Opoku-Anane, Kim Chi Vo, Evelina Manvelyan, Sushmita Sen, Zhanna Ghukasyan, Frances Collins, Xavier Santamaria, Philippa Saunders, Kord Kober, Allan F. McRae, Kathryn L. Terry, Júlia Vallvé-Juanico, Christian Becker, Peter A. W. Rogers, Juan C. Irwin, Krina Zondervan, Grant W. Montgomery, Stacey Missmer, Marina Sirota, Linda Giudice
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-17 (2023)
Abstract Endometriosis is a leading cause of pain and infertility affecting millions of women globally. Herein, we characterize variation in DNA methylation (DNAm) and its association with menstrual cycle phase, endometriosis, and genetic variants th
Externí odkaz:
https://doaj.org/article/f61d2545020c46a2baff0d24cc8d121a
Autor:
Dora B Balogh, Gernot Hudelist, Dmitrijs Bļizņuks, Jayanth Raghothama, Christian M Becker, Roman Horace, Harald Krentel, Andrew W Horne, Nicolas Bourdel, Gabriella Marki, Carla Tomassetti, Ulrik Bak Kirk, Nandor Acs, Attila Bokor
Publikováno v:
PLoS ONE, Vol 19, Iss 5, p e0300186 (2024)
IntroductionEndometriosis is a chronic disease that affects up to 190 million women and those assigned female at birth and remains unresolved mainly in terms of etiology and optimal therapy. It is defined by the presence of endometrium-like tissue ou
Externí odkaz:
https://doaj.org/article/f8de5814722340358a49294e5aa8a6c8
Autor:
Scott C. Mackenzie, Jacqueline Stephen, Linda Williams, Jane Daniels, John Norrie, Christian M. Becker, Dominic Byrne, Ying Cheong, T. Justin Clark, Kevin G. Cooper, Emma Cox, Ann M. Doust, Priscilla Fernandez, Jeremy Hawe, Tom Holland, Lone Hummelshoj, Louise J. Jackson, Kathleen King, Abha Maheshwari, Dan C. Martin, Lauren Sutherland, Jim Thornton, Katy Vincent, Sanjay Vyas, Andrew W. Horne, Lucy H. R. Whitaker
Publikováno v:
Trials, Vol 24, Iss 1, Pp 1-15 (2023)
Abstract Background Endometriosis affects 190 million women and those assigned female at birth worldwide. For some, it is associated with debilitating chronic pelvic pain. Diagnosis of endometriosis is often achieved through diagnostic laparoscopy. H
Externí odkaz:
https://doaj.org/article/e378d0205550443986bcd63318413961
Publikováno v:
Reproduction and Fertility, Vol 4, Iss 2, Pp 1-9 (2023)
Patients with chronic pelvic pain (CPP) may experience pain exacerbations requiring hospital admissions. Due to the effects of backlogged elective surgeries and outpatient gynaecology appointments resulting from the COVID-19 pandemic, we hypothesised
Externí odkaz:
https://doaj.org/article/b37e2e3a5e8f4818bd22eb98bf811e2a
Publikováno v:
Reproduction and Fertility, Vol 4, Iss 2, Pp 1-3 (2023)
An ectopic pregnancy occurs when an embryo implants outside of the uterus, usually in a fallopian tube. When detected early, treatment is often with a medication called methotrexate. When methotrexate does not work, surgery is required. A recent clin
Externí odkaz:
https://doaj.org/article/416c5a4a1b9240bf9147cb48c79e5e58
Autor:
Lysia Demetriou, Michal Krassowski, Pedro Abreu Mendes, Kurtis Garbutt, Allison F. Vitonis, Elizabeth Wilkins, Lydia Coxon, Lars Arendt-Nielsen, Qasim Aziz, Judy Birch, Andrew W. Horne, Anja Hoffman, Lone Hummelshoj, Claire E. Lunde, Jane Meijlink, Danielle Perro, Nilufer Rahmioglu, Kathryn L. Terry, Esther Pogatzki-Zahn, Christine B. Sieberg, Rolf-Detlef Treede, Christian M. Becker, Francisco Cruz, Stacey A. Missmer, Krina T. Zondervan, Jens Nagel, Katy Vincent
Publikováno v:
Frontiers in Reproductive Health, Vol 5 (2023)
IntroductionChronic pelvic pain (CPP) is a common condition affecting up to 26.6% of women, with many suffering for several years before diagnosis and/or treatment. Its clinical presentation is varied and there are frequently comorbid conditions both
Externí odkaz:
https://doaj.org/article/f24c4c3f6d2e4bcfb363810047da7318