Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Andrew Vorobyov"'
Autor:
Mateusz Putyrski, Olesya Vakhrusheva, Florian Bonn, Suchithra Guntur, Andrew Vorobyov, Christian Brandts, Ivan Dikic, Andreas Ernst
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Short linear motifs (SLiMs) located in disordered regions of multidomain proteins are important for the organization of protein–protein interaction networks. By dynamic association with their binding partners, SLiMs enable assembly of multiprotein
Externí odkaz:
https://doaj.org/article/f0bd0116cf534677a1686341a8329d36
Autor:
Ivan Dikic, Maria Kuzikov, Andreas Ernst, Gabor Varga, Michael J. Parnham, Veronique Schaeffer, Masato Akutsu, Mateusz Putyrski, Andrew Vorobyov, Timurs Maculins, Volker Dötsch, Sachdev S. Sidhu, Jakob Gebel, Simin Rahighi, Andrea Zaliani, Javier Garcia-Pardo, Anamarija Skenderovic, Philipp Busse
Publikováno v:
Cell Chemical Biology. 27:1441-1451.e7
Protein-protein interactions (PPIs) govern intracellular life, and identification of PPI inhibitors is challenging. Roadblocks in assay development stemming from weak binding affinities of natural PPIs impede progress in this field. We postulated tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c154f37519cc7706af1c06ee4352c6d4
https://doi.org/10.1016/j.chembiol.2020.07.010
https://doi.org/10.1016/j.chembiol.2020.07.010
Autor:
Amélie Fradet-Turcotte, Leo C. K. Wan, Daniel Durocher, Andrew Vorobyov, Sachdev S. Sidhu, Yu Chi Juang, F Sicheri, TF Ng, Weilian Zhang, Alexandre Orthwein, Wilson, Sylvie M. Noordermeer, M Zimmermann, Andreas Ernst, Canny, Meagan Munro, N Moatti
The expanding repertoire of programmable nucleases such as Cas9 brings new opportunities in genetic medicine1–3. In many cases, these nucleases are engineered to induce a DNA double-strand break (DSB) to stimulate precise genome editing by homologo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::177b6b00a157a890234a014fe98f34a4
Autor:
Elton Zeqiraj, Laurence Pelletier, Jason Moffat, Sirano Dhe-Paganon, Avinash Persaud, Konstantina Karamboulas, Michael Moran, Pak-Kei Chan, Dante Neculai, Philipp Alberts, Yanling Zhao, Andrew Vorobyov, Daniel Durocher, John R. Walker, Daniela Rotin, Brian Raught, Andreas Ernst, George V. Avvakumov, Abdellah Allali-Hassani, Masoud Vedadi, Pankaj Garg, Yu Chi Juang, Marie-Claude Landry, Linda G. Beatty, Christina Yeh, Ana-Mirela Neculai, Mike Tyers, Yihui Fan, Jiefei Tong, Frank Sicheri, Sachdev S. Sidhu, Jianhua Yang
Publikováno v:
Science (New York, N.Y.). 339(6119)
Modifying Deubiquitinases Protein ubiquitination is a widespread mechanism for cellular regulation, and new regulators are valuable research tools and may help to generate therapeutic small molecules. Ernst et al. (p. 590 , published online 3 January
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41cc99d73f0382c808fe0b4e737df16d
https://pubmed.ncbi.nlm.nih.gov/23287719
https://pubmed.ncbi.nlm.nih.gov/23287719
Autor:
Emmanuel Lemichez, Brenda A. Schulman, Zhenyue Hao, Sachdev S. Sidhu, Nan Li, Ryan Murchie, Wei Zhang, Maria A. Sartori, Kuen-Phon Wu, Jason Moffat, John R. Walker, Avinash Persaud, Yi Sheng, Alban Ordureau, Jicheng Hu, Chong Jiang, Manjeet Mukherjee, Kevin R. Brown, Yufeng Tong, Yanjun Li, Junjie Chen, Anne Doye, Peter Y. Mercredi, Daniela Rotin, Hari B. Kamadurai, J. Wade Harper
Publikováno v:
Molecular Cell
Molecular Cell, Elsevier, 2016, 62 (1), pp.121-136. ⟨10.1016/j.molcel.2016.02.005⟩
Molecular Cell, Elsevier, 2016, 62 (1), pp.121-136. ⟨10.1016/j.molcel.2016.02.005⟩
Comment in : A Billion Ubiquitin Variants to Probe and Modulate the UPS. [Mol Cell. 2016]; International audience; HECT-family E3 ligases ubiquitinate protein substrates to control virtually every eukaryotic process and are misregulated in numerous d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c0423280b3710b384d45c649c83c073
https://doi.org/10.1016/j.molcel.2016.02.005
https://doi.org/10.1016/j.molcel.2016.02.005