Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Andrew Uzilov"'
Autor:
Huan Wang, Nina Bhardwaj, Naoko Imai, Seunghee Kim-Schulze, Takuro Saito, Jingjing Qi, Sacha Gnjatic, Sumanta K Pal, Matthew D Galsky, Manishkumar Patel, Hui Xie, Robert Sebra, Andrew Uzilov, Jonathan Anker, Rebecca Halperin, Shingo Eikawa, Noah M Hahn
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 8 (2023)
Cisplatin-based chemotherapy has been associated with durable disease control in a small subset of patients with metastatic urothelial cancer. However, the mechanistic basis for this phenomenon has remained elusive. Antitumor immunity may underlie th
Externí odkaz:
https://doaj.org/article/55cbcba3ae0649aeb88c87f1c18bdaa7
Autor:
Esra Karakose, Huan Wang, William Inabnet, Rajesh V. Thakker, Steven Libutti, Gustavo Fernandez-Ranvier, Hyunsuk Suh, Mark Stevenson, Yayoi Kinoshita, Michael Donovan, Yevgeniy Antipin, Yan Li, Xiaoxiao Liu, Fulai Jin, Peng Wang, Andrew Uzilov, Carmen Argmann, Eric E. Schadt, Andrew F. Stewart, Donald K. Scott, Luca Lambertini
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Insulinomas are rare, benign beta cell tumours which overproduce insulin and have been associated to epigenetic alterations. Here the authors characterise insulinoma methylomes, finding changes in promoter methylation and chromatin structure proposed
Externí odkaz:
https://doaj.org/article/1d219e060ef14af69f480f879ef60196
Autor:
Elena Pereira, Olga Camacho-Vanegas, Sanya Anand, Robert Sebra, Sandra Catalina Camacho, Leopold Garnar-Wortzel, Navya Nair, Erin Moshier, Melissa Wooten, Andrew Uzilov, Rong Chen, Monica Prasad-Hayes, Konstantin Zakashansky, Ann Marie Beddoe, Eric Schadt, Peter Dottino, John A Martignetti
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0145754 (2015)
BACKGROUND:High-grade serous ovarian and endometrial cancers are the most lethal female reproductive tract malignancies worldwide. In part, failure to treat these two aggressive cancers successfully centers on the fact that while the majority of pati
Externí odkaz:
https://doaj.org/article/9c3dffebfa4d46e4b9673bbaa1836c2f
Autor:
Josep M. Llovet, Daniela Sia, Sasan Roayaie, Xavier Forns, Jaclyn Neely, Andrew Uzilov, Jessica Zucman-Rossi, Eric Letouzé, Jigjidsuren Chinburen, Swan Thung, Sofía Pérez-del-Pulgar, Augusto Villanueva, Amankyeldi Yerbolat, Erdenebileg Taivanbaatar, Chinbold Enkhbold, Genís Campreciós, Patricia Taik, Ajay Ramakrishnan Varadarajan, Sara Torrecilla, Carla Montironi, Wei Qiang Leow, Roger Esteban-Fabró, Mireia García-López, Thais Leonel, Philipp K. Haber, Miho Maeda, Huan Wang, Miguel Torres-Martín, Marc Puigvehí, Laura Torrens
Supplementary Data from Hepatocellular Carcinoma in Mongolia Delineates Unique Molecular Traits and a Mutational Signature Associated with Environmental Agents
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f6bb4df5a2b7bd7decdb4928d4ceb9e
https://doi.org/10.1158/1078-0432.22488728.v1
https://doi.org/10.1158/1078-0432.22488728.v1
Autor:
Josep M. Llovet, Daniela Sia, Sasan Roayaie, Xavier Forns, Jaclyn Neely, Andrew Uzilov, Jessica Zucman-Rossi, Eric Letouzé, Jigjidsuren Chinburen, Swan Thung, Sofía Pérez-del-Pulgar, Augusto Villanueva, Amankyeldi Yerbolat, Erdenebileg Taivanbaatar, Chinbold Enkhbold, Genís Campreciós, Patricia Taik, Ajay Ramakrishnan Varadarajan, Sara Torrecilla, Carla Montironi, Wei Qiang Leow, Roger Esteban-Fabró, Mireia García-López, Thais Leonel, Philipp K. Haber, Miho Maeda, Huan Wang, Miguel Torres-Martín, Marc Puigvehí, Laura Torrens
Purpose:Mongolia has the world's highest incidence of hepatocellular carcinoma (HCC), with ∼100 cases/100,000 inhabitants, although the reasons for this have not been thoroughly delineated.Experimental Design:We performed a molecular characterizati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bd3cbdba86e150e6ffc7b50358bfc4a
https://doi.org/10.1158/1078-0432.c.6532793.v1
https://doi.org/10.1158/1078-0432.c.6532793.v1
Autor:
Josep M. Llovet, Daniela Sia, Sasan Roayaie, Xavier Forns, Jaclyn Neely, Andrew Uzilov, Jessica Zucman-Rossi, Eric Letouzé, Jigjidsuren Chinburen, Swan Thung, Sofía Pérez-del-Pulgar, Augusto Villanueva, Amankyeldi Yerbolat, Erdenebileg Taivanbaatar, Chinbold Enkhbold, Genís Campreciós, Patricia Taik, Ajay Ramakrishnan Varadarajan, Sara Torrecilla, Carla Montironi, Wei Qiang Leow, Roger Esteban-Fabró, Mireia García-López, Thais Leonel, Philipp K. Haber, Miho Maeda, Huan Wang, Miguel Torres-Martín, Marc Puigvehí, Laura Torrens
Supplementary Figure from Hepatocellular Carcinoma in Mongolia Delineates Unique Molecular Traits and a Mutational Signature Associated with Environmental Agents
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31fc68007438aaaa460800152dbffb77
https://doi.org/10.1158/1078-0432.22488698.v1
https://doi.org/10.1158/1078-0432.22488698.v1
Autor:
John A. Martignetti, Peter Dottino, Morten Mau-Sørensen, Mansoor R. Mirza, Michael Kauffman, Tami Rashal, Yosef Landesman, Dilara McCauley, Sharon Shacham, Jean-Noel Billaud, Richard Halpert, Rileen Sinha, Rong Chen, Andrew Uzilov, Robert Sebra, Tamara Kalir, Faisal Khan, Michael Donovan, Estefania Rodriguez, Nolan Priedigkeit, Fei Huang, Susan J. Ramus, Brad R. Evans, Elena Pereira, Eva Kalir, John F. Gerecitano, Nashat Y. Gabrail, Albiruni R.A. Razak, Thomas R. Silvers, Sandra Catalina Camacho, Ying Chen
Supplementary Material and Method
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bd94388a9ace123fadf893e903e3182
https://doi.org/10.1158/1078-0432.22464165.v1
https://doi.org/10.1158/1078-0432.22464165.v1
Autor:
John A. Martignetti, Peter Dottino, Morten Mau-Sørensen, Mansoor R. Mirza, Michael Kauffman, Tami Rashal, Yosef Landesman, Dilara McCauley, Sharon Shacham, Jean-Noel Billaud, Richard Halpert, Rileen Sinha, Rong Chen, Andrew Uzilov, Robert Sebra, Tamara Kalir, Faisal Khan, Michael Donovan, Estefania Rodriguez, Nolan Priedigkeit, Fei Huang, Susan J. Ramus, Brad R. Evans, Elena Pereira, Eva Kalir, John F. Gerecitano, Nashat Y. Gabrail, Albiruni R.A. Razak, Thomas R. Silvers, Sandra Catalina Camacho, Ying Chen
Supplementary Figure 1. Overview of XPO1's role in nuclear:cytoplasmic transport. Supplementary Figure 2. KPT-185 is much less toxic to patient-derived benign cells than patient-derived serous high grade OvCa cells. Supplementary Figure 3. FACS cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bda5ace0e09d7253667d7c8ae0026f8
https://doi.org/10.1158/1078-0432.22464168
https://doi.org/10.1158/1078-0432.22464168
Autor:
John A. Martignetti, Peter Dottino, Morten Mau-Sørensen, Mansoor R. Mirza, Michael Kauffman, Tami Rashal, Yosef Landesman, Dilara McCauley, Sharon Shacham, Jean-Noel Billaud, Richard Halpert, Rileen Sinha, Rong Chen, Andrew Uzilov, Robert Sebra, Tamara Kalir, Faisal Khan, Michael Donovan, Estefania Rodriguez, Nolan Priedigkeit, Fei Huang, Susan J. Ramus, Brad R. Evans, Elena Pereira, Eva Kalir, John F. Gerecitano, Nashat Y. Gabrail, Albiruni R.A. Razak, Thomas R. Silvers, Sandra Catalina Camacho, Ying Chen
Purpose: The high fatality-to-case ratio of ovarian cancer is directly related to platinum resistance. Exportin-1 (XPO1) is a nuclear exporter that mediates nuclear export of multiple tumor suppressors. We investigated possible clinicopathologic corr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0145a7f4193fe36b646da6771fbef93b
https://doi.org/10.1158/1078-0432.c.6525636.v1
https://doi.org/10.1158/1078-0432.c.6525636.v1
Autor:
John A. Martignetti, Peter Dottino, Morten Mau-Sørensen, Mansoor R. Mirza, Michael Kauffman, Tami Rashal, Yosef Landesman, Dilara McCauley, Sharon Shacham, Jean-Noel Billaud, Richard Halpert, Rileen Sinha, Rong Chen, Andrew Uzilov, Robert Sebra, Tamara Kalir, Faisal Khan, Michael Donovan, Estefania Rodriguez, Nolan Priedigkeit, Fei Huang, Susan J. Ramus, Brad R. Evans, Elena Pereira, Eva Kalir, John F. Gerecitano, Nashat Y. Gabrail, Albiruni R.A. Razak, Thomas R. Silvers, Sandra Catalina Camacho, Ying Chen
Supplementary Figure Legend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37be2227d7e7d5b4425f5fb0ff89b03d
https://doi.org/10.1158/1078-0432.22464174.v1
https://doi.org/10.1158/1078-0432.22464174.v1