Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Andrew T.C. Tsin"'
Publikováno v:
Journal of Lipid Research, Vol 39, Iss 3, Pp 604-612 (1998)
In the eye, hydrolysis of stored retinyl esters is catalyzed by retinyl ester hydrolase (REH) activities in retinal pigment epithelium (RPE) membranes. In the present study, biochemical analyses were conducted to determine the substrate specificity o
Externí odkaz:
https://doaj.org/article/25b1140ecaa74eb8a9e19dc0ee83d7f0
Publikováno v:
Cell Biology & Cell Metabolism. 3:1-4
Previous studies have shown that in diabetic patients, there is an increase of retinal capillaries associated with the development of diabetic retinopathy in the eye. The objective of current study is to investigate the effect of glucose on retinal e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e977301e07cea18a0c656f3b736bc6e
https://doi.org/10.24966/cbcm-1943/100008
https://doi.org/10.24966/cbcm-1943/100008
Publikováno v:
The Open Neurology Journal
The aim of this research is to determine whether oxidative stress induces cellular senescence in human retinal pigment epithelial cells. Cultured ARPE19 cells were subjected to different concentrations of hydrogen peroxide to induce oxidative stress.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfefc907241a0d85b5a75e25d641c766
http://europepmc.org/articles/PMC5012081
http://europepmc.org/articles/PMC5012081
Autor:
Reto Asmis, Clyde F. Phelix, Robert J. Moritz, Rajesha Rupaimoole, Hong Seok Kim, Andrew T.C. Tsin, Richard G. LeBaron
Publikováno v:
International Journal of Clinical Medicine. :496-510
Metabolically stressed kidney is in part characterized by infiltrating macrophages and macrophage-derived TGF-β1 that promote the synthesis of various ECM molecules. TGF-β1 strongly enhances the expression of the gene TGFBI that encodes a cell-adhe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::044eefb62e4abf8bd447e9b734bd72db
https://doi.org/10.4236/ijcm.2016.77055
https://doi.org/10.4236/ijcm.2016.77055
Autor:
Brian Yust, Dhiraj K. Sardar, Federico Gonzalez-Fernandez, Brandi S Betts-Obregon, Joshua Mimun, Andrew T.C. Tsin, Dongjin Sung
Publikováno v:
Photochemistry and Photobiology. 91:371-378
Retinol degrades rapidly in light into a variety of photoproducts. It is remarkable that visual cycle retinoids can evade photodegradation as they are exchanged between the photoreceptors, retinal pigment epithelium and Müller glia. Within the inter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad02720e830df0ae60724b89dca8dbdf
https://doi.org/10.1111/php.12416
https://doi.org/10.1111/php.12416
Autor:
Iram P. Rodriguez-Sanchez, Antonio Alí Pérez-Maya, Carlos Arámburo, Diana Cristina Pérez-Ibave, Hugo A. Barrera-Saldaña, Jesus Mohamed-Hamsho, Andrew T.C. Tsin, María Lourdes Garza-Rodríguez, Maricela Luna, Karim Mohamed-Noriega, George Perry, Jibran Mohamed-Noriega, Humberto Cavazos-Adame
Publikováno v:
Experimental eye research. 169
The human growth hormone (GH) locus is comprised by two GH (GH1 and GH2) genes and three chorionic somatomammotropin (CSH1, CSH2 and CSH-L) genes. While GH1 is expressed in the pituitary gland, the rest are expressed in the placenta. However, GH1 is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::226eb5486a464b668177957f08e029ba
https://pubmed.ncbi.nlm.nih.gov/29407222
https://pubmed.ncbi.nlm.nih.gov/29407222
Publikováno v:
Europe PubMed Central
Purpose: Diabetic retinopathy is manifested by excessive angiogenesis and high level of vascular endothelial growth factor (VEGF) in the eye. Methods: Human (MIO-M1) and rat (rMC-1) Müller cells were treated with 0, 5.5, or 30mM glucose for 24 hours
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40c18613498d078b3379e04d9053b8f5
Background: Rb1 is a ginsenoside steroid glycoside found exclusively in the plant Panax ginseng. In an earlier report, we showed that Rb1 increased cell proliferation and reduced VEGF (vascular endothelial growth factor) secretion by human retinal pi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::625a030d4d1b10f838d7496beb688581
https://europepmc.org/articles/PMC5425158/
https://europepmc.org/articles/PMC5425158/
Publikováno v:
Biophysical chemistry.
Human carbonic anhydrase II (hCAII) represents an ultimate example of the perfectly efficient metalloenzymes, which is capable of catalyzing the hydration of carbon dioxide with a rate approaching the diffusion controlled limit. Extensive experimenta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7025133c994794ae4f73f4cf053c2dad
https://pubmed.ncbi.nlm.nih.gov/27232456
https://pubmed.ncbi.nlm.nih.gov/27232456
Autor:
Federico Gonzalez-Fernandez, Reto Asmis, Richard G. LeBaron, Andrew T.C. Tsin, Andrew S. Mendiola, Brandi S Betts-Obregon, Albert A. Mondragon, T Zou
Publikováno v:
Eye (London, England). 30(12)
PurposeOne of the earliest hallmarks of diabetic retinopathy is the loss of retinal pericytes. However, the mechanisms that promote pericyte dropout are unknown. In the present study, we propose a novel pathway in which pericyte apoptosis is mediated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::815bba56bfbaad1853e308fbeb3eff79
https://pubmed.ncbi.nlm.nih.gov/27564721
https://pubmed.ncbi.nlm.nih.gov/27564721