Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Andrew T. McCulloch"'
Autor:
Alessia Floerchinger, Kendelle J. Murphy, Sharissa L. Latham, Sean C. Warren, Andrew T. McCulloch, Young-Kyung Lee, Janett Stoehr, Pauline Mélénec, Cris S. Guaman, Xanthe L. Metcalf, Victoria Lee, Anaiis Zaratzian, Andrew Da Silva, Michael Tayao, Sonia Rolo, Monica Phimmachanh, Ghazal Sultani, Laura McDonald, Susan M. Mason, Nicola Ferrari, Lisa M. Ooms, Anna-Karin E. Johnsson, Heather J. Spence, Michael F. Olson, Laura M. Machesky, Owen J. Sansom, Jennifer P. Morton, Christina A. Mitchell, Michael S. Samuel, David R. Croucher, Heidi C.E. Welch, Karen Blyth, C. Elizabeth Caldon, David Herrmann, Kurt I. Anderson, Paul Timpson, Max Nobis
Publikováno v:
Cell Reports, Vol 36, Iss 11, Pp 109689- (2021)
Summary: Assessing drug response within live native tissue provides increased fidelity with regards to optimizing efficacy while minimizing off-target effects. Here, using longitudinal intravital imaging of a Rac1-Förster resonance energy transfer (
Externí odkaz:
https://doaj.org/article/60a7564e516e42fe894cc587d92fc98e
Autor:
James R. W. Conway, Sean C. Warren, Young-Kyung Lee, Andrew T. McCulloch, Astrid Magenau, Victoria Lee, Xanthe L. Metcalf, Janett Stoehr, Katharina Haigh, Lea Abdulkhalek, Cristian S. Guaman, Daniel A. Reed, Kendelle J. Murphy, Brooke A. Pereira, Pauline Mélénec, Cecilia Chambers, Sharissa L. Latham, Helen Lenthall, Elissa K. Deenick, Yuanqing Ma, Tri Phan, Elgene Lim, Anthony M. Joshua, Stacey Walters, Shane T. Grey, Yan-Chuan Shi, Lei Zhang, Herbert Herzog, David R. Croucher, Andy Philp, Colinda L.G.J. Scheele, David Herrmann, Owen J. Sansom, Jennifer P. Morton, Antonella Papa, Jody J. Haigh, Max Nobis, Paul Timpson
Publikováno v:
Science Advances. 9
Aberrant AKT activation occurs in a number of cancers, metabolic syndrome, and immune disorders, making it an important target for the treatment of many diseases. To monitor spatial and temporal AKT activity in a live setting, we generated an Akt-FRE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b6f9949213693722c610a68b2040bc6
https://doi.org/10.1126/sciadv.adf9063
https://doi.org/10.1126/sciadv.adf9063
Autor:
Laura M. Machesky, Sharissa L. Latham, Karen Blyth, Owen J. Sansom, Paul Timpson, Cris S. Guaman, Victoria Lee, Nicola Ferrari, Anaiis Zaratzian, Sean C. Warren, Susan M. Mason, Pauline Mélénec, Lisa M Ooms, C. Elizabeth Caldon, Andrew M. Da Silva, Andrew T. McCulloch, Michael F. Olson, Xanthe L. Metcalf, Ghazal Sultani, Monica Phimmachanh, David Herrmann, Michael Tayao, Max Nobis, Alessia Floerchinger, Janett Stoehr, Jennifer P. Morton, Anna-Karin E. Johnsson, Christina Anne Mitchell, Heather J. Spence, Kendelle J. Murphy, David R. Croucher, Sonia Rolo, Heidi C.E. Welch, Young-Kyung Lee, Michael S. Samuel, Laura McDonald, Kurt I. Anderson
Publikováno v:
Cell Reports, Vol 36, Iss 11, Pp 109689-(2021)
Assessing drug response within live native tissue provides increased fidelity with regards to optimizing efficacy while minimizing off-target effects. Here, using longitudinal intravital imaging of a Rac1-Forster resonance energy transfer (FRET) bios
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e60a0a238c9fea39f12263962e274fc
