Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Andrew T. M. Bagshaw"'
Autor:
Andrew T M Bagshaw, L John Horwood, Youfang Liu, David M Fergusson, Patrick F Sullivan, Martin A Kennedy
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e55208 (2013)
Variation in human intelligence is approximately 50% heritable, but understanding of the genes involved is limited. Several forms of genetic variation remain under-studied in relation to intelligence, one of which is copy number variation (CNV). Usin
Externí odkaz:
https://doaj.org/article/9df9db90c7fd4aa3b45b57ba2b21215f
Autor:
Andrew T. M. Bagshaw
Publikováno v:
Genome Biology and Evolution
Microsatellite repeat DNA is best known for its length mutability, which is implicated in several neurological diseases and cancers, and often exploited as a genetic marker. Less well-known is the body of work exploring the widespread and surprisingl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d845e5b7d669bff14cde74c72b9476d3
https://pubmed.ncbi.nlm.nih.gov/28957459
https://pubmed.ncbi.nlm.nih.gov/28957459
Publikováno v:
Nucleic Acids Research
Short tandem repeats (STR) are ubiquitous components of the genomic architecture of most living organisms. Recent work has highlighted the widespread functional significance of such repeats, particularly around gene regulation, but the mutational pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b66c2498192cd0e279d1649173e3a13f
https://pubmed.ncbi.nlm.nih.gov/29300948
https://pubmed.ncbi.nlm.nih.gov/29300948
Autor:
Andrew T. M. Bagshaw, Martin A. Kennedy, Neil J. Gemmell, L. John Horwood, David M. Fergusson
Publikováno v:
BMC Medical Genetics
Background The genetic and environmental influences on human personality and behaviour are a complex matter of ongoing debate. Accumulating evidence indicates that short tandem repeats (STRs) in regulatory regions are good candidates to explain herit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33e3b3d7e36057a0e0262cac67a50e5c
https://pubmed.ncbi.nlm.nih.gov/28158988
https://pubmed.ncbi.nlm.nih.gov/28158988
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e113862 (2014)
PLoS ONE
PLoS ONE
To date we have little knowledge of how accurate next-generation sequencing (NGS) technologies are in sequencing repetitive sequences beyond known limitations to accurately sequence homopolymers. Only a handful of previous reports have evaluated the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e364f4fab4c4013bcbe22f16b4ddbde
http://europepmc.org/articles/PMC4250034?pdf=render
http://europepmc.org/articles/PMC4250034?pdf=render
Autor:
Emmanuel Buschiazzo, Angelika Merkel, Neil J. Gemmell, Andrew T. M. Bagshaw, Iris M. Vargas Jentzsch
Publikováno v:
eLS
Microsatellites are highly mutable nucleotide arrays composed of short motifs repeated in tandem. They are ubiquitously distributed in bacterial and eukaryotic genomes and their abundance and mutability has made them a widely used genetic marker for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46839c35e314439d043dc898382041fe
https://doi.org/10.1002/9780470015902.a0020847.pub2
https://doi.org/10.1002/9780470015902.a0020847.pub2
Autor:
Youfang Liu, David M. Fergusson, Martin A. Kennedy, L. John Horwood, Andrew T. M. Bagshaw, Patrick F. Sullivan
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 1, p e55208 (2013)
PLoS ONE, Vol 8, Iss 1, p e55208 (2013)
Variation in human intelligence is approximately 50% heritable, but understanding of the genes involved is limited. Several forms of genetic variation remain under-studied in relation to intelligence, one of which is copy number variation (CNV). Usin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83e7e51b260d375f1fee33a76ff35252
http://europepmc.org/articles/PMC3559383
http://europepmc.org/articles/PMC3559383
Autor:
Chih-Lin Hsieh, Neil J. Gemmell, Markus Müschen, Albert G. Tsai, Andrew T. M. Bagshaw, Noritaka Adachi, Xiaoping Cui, Aya Kurosawa, Zhengfei Lu, Michael R. Lieber, Lars Klemm
Publikováno v:
Molecular and cellular biology. 33(5)
The t(14;18) chromosomal translocation typically involves breakage at the bcl-2 major breakpoint region (MBR) to cause human follicular lymphoma. A theory to explain the striking propensity of the MBR breaks at three CpG clusters within the 175-bp MB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed07276d1599e26ba55498da630f07fb
https://pubmed.ncbi.nlm.nih.gov/23263985
https://pubmed.ncbi.nlm.nih.gov/23263985
Autor:
Andrew T. M. Bagshaw, Pankaj Kumar, Neil J. Gemmell, Shantanu Chowdhury, Michael A. Black, Sterling Sawaya, Emmanuel Buschiazzo
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 2, p e54710 (2013)
PLoS ONE, Vol 8, Iss 2, p e54710 (2013)
Tandem repeats are genomic elements that are prone to changes in repeat number and are thus often polymorphic. These sequences are found at a high density at the start of human genes, in the gene's promoter. Increasing empirical evidence suggests tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e48b7e91dae13baad0830938a561cd5
https://pubmed.ncbi.nlm.nih.gov/23405090
https://pubmed.ncbi.nlm.nih.gov/23405090
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9781461454335
Microsatellites in and around genes have been shown to modulate levels of gene expression in multiple organisms, ranging from bacteria to humans. Here we will discuss promoter microsatellites known to modulate gene expression, with a few key examples
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb62dfc400ea3ee04e63a7c68095674e
https://doi.org/10.1007/978-1-4614-5434-2_4
https://doi.org/10.1007/978-1-4614-5434-2_4
