Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Andrew T. Cheng"'
Autor:
Laura M Sanchez, Andrew T Cheng, Christopher J A Warner, Loni Townsley, Kelly C Peach, Gabriel Navarro, Nicholas J Shikuma, Walter M Bray, Romina M Riener, Fitnat H Yildiz, Roger G Linington
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0149603 (2016)
Biofilms are a ubiquitous feature of microbial community structure in both natural and host environments; they enhance transmission and infectivity of pathogens and provide protection from human defense mechanisms and antibiotics. However, few natura
Externí odkaz:
https://doaj.org/article/7730c676432941e89b9355fd21c305ee
Publikováno v:
PLoS Pathogens, Vol 11, Iss 5, p e1004933 (2015)
Two-component signal transduction systems (TCS) are used by bacteria to sense and respond to their environment. TCS are typically composed of a sensor histidine kinase (HK) and a response regulator (RR). The Vibrio cholerae genome encodes 52 RR, but
Externí odkaz:
https://doaj.org/article/42b9e9b444da400f9056f1f6c7debe8b
Autor:
Brittany De Temple, Kitty Yale, Andrew T. Cheng, Reshma Shringarpure, Erik J. Tillman, Erica Fong, Juan P. Frias, Timothy P Rolph, Stephen A. Harrison
Publikováno v:
Diabetes. 70
FGF21, an endocrine hormone that regulates whole-body metabolism during energy imbalance, is a promising therapeutic target. Efruxifermin (EFX), an Fc-FGF21 analog, is a balanced FGFR1c, 2c, and 3c agonist under investigation as a potential treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3223bcfab354a7efac3d969bd1526417
https://doi.org/10.2337/db21-119-lb
https://doi.org/10.2337/db21-119-lb
Autor:
Tianyan Song, Dharmesh Sabharwal, Jyoti Mohan Gurung, Andrew T Cheng, Annika E Sjöström, Fitnat H Yildiz, Bernt Eric Uhlin, Sun Nyunt Wai
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e101280 (2014)
Vibrio cholerae biofilms contain exopolysaccharide and three matrix proteins RbmA, RbmC and Bap1. While much is known about exopolysaccharide regulation, little is known about the mechanisms by which the matrix protein components of biofilms are regu
Externí odkaz:
https://doaj.org/article/36c5d87a7f4442be862459bf4f132fb1
Autor:
Achal Deo, Andrew T. Cheng, John Eid, Jessica Gines, Mohan S. Iyer, Brendon Stoneburner, Marcus F. Schicklberger, James H. Bullard, Michael Souza, Surabhi Tyagi, Madeleine Nemchek, Wesley T Loo, Orville G. Kolterman, Colleen Cutcliffe, Nicholas B. Justice, Paul J. McMurdie, Fanny Perraudeau
Publikováno v:
BMJ Open Diabetes Research & Care
BMJ Open Diabetes Research & Care, Vol 8, Iss 1 (2020)
BMJ Open Diabetes Research & Care, Vol 8, Iss 1 (2020)
IntroductionA growing body of evidence suggests that specific, naturally occurring gut bacteria are under-represented in the intestinal tracts of subjects with type 2 diabetes (T2D) and that their functions, like gut barrier stability and butyrate pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b857f5ff35452fbf523decbd3c78ef7f
http://europepmc.org/articles/PMC7368581
http://europepmc.org/articles/PMC7368581
Autor:
Andrew T. Cheng, Fanny Perraudeau, Jessica Gines, Mohan S. Iyer, John Eid, Colleen Cutcliffe, James H. Bullard, Brendon Stoneburner, Paul J. McMurdie, Orville G. Kolterman, Marcus F. Schicklberger, Nicholas B. Justice, Surabhi Tyagi
Publikováno v:
Diabetes. 68
Studies show that BP+MR are decreased inT2D; the impact of administering specific strains has not been reported. A 12-week, double blind, placebo-controlled study of 2 MFs prepared GMP using only GRAS constituents (MF-1: BP; MF-2: BP + MR) in T2D (dr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d64ab29531e03730cb77a2ce58fa1a3d
https://doi.org/10.2337/db19-758-p
https://doi.org/10.2337/db19-758-p
Publikováno v:
Journal of Bacteriology. 200
The biofilm growth mode is important in both the intestinal and environmental phases of the Vibrio cholerae life cycle. Regulation of biofilm formation involves several transcriptional regulators and alternative sigma factors. One such factor is the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2eca16b79c5be558091466dd29b6b957
https://doi.org/10.1128/jb.00025-18
https://doi.org/10.1128/jb.00025-18
Publikováno v:
Journal of bacteriology. 200(15)
Biofilms play an important role in the Vibrio cholerae life cycle, contributing to both environmental survival and transmission to a human host. Identifying key regulators of V. cholerae biofilm formation is necessary to fully understand how this imp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::34d426c719d6cc441b41bf17ef226891
https://pubmed.ncbi.nlm.nih.gov/29735756
https://pubmed.ncbi.nlm.nih.gov/29735756
Publikováno v:
Journal of bacteriology. 199(18)
Two-component signal transduction systems (TCSs), typically composed of a sensor histidine kinase (HK) and a response regulator (RR), are the primary mechanism by which pathogenic bacteria sense and respond to extracellular signals. The pathogenic ba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5d0984995d588d7d95cb2fc4393a3fa
https://pubmed.ncbi.nlm.nih.gov/28607158
https://pubmed.ncbi.nlm.nih.gov/28607158
Autor:
Gabriel Navarro, Andrew T. Cheng, Fitnat H. Yildiz, Roger G. Linington, Kelly C. Peach, Walter M. Bray, Valerie S. Bernan
Publikováno v:
Antimicrobial Agents and Chemotherapy. 58:1092-1099
To date, most antibiotics have primarily been developed to target bacteria in the planktonic state. However, biofilm formation allows bacteria to develop tolerance to antibiotics and provides a mechanism to evade innate immune systems. Therefore, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75f6100c065b1663151bfdc68630f387
https://doi.org/10.1128/aac.01781-13
https://doi.org/10.1128/aac.01781-13