Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Andrew T Quaile"'
Autor:
Malene L Urbanus, Andrew T Quaile, Peter J Stogios, Mariya Morar, Chitong Rao, Rosa Di Leo, Elena Evdokimova, Mandy Lam, Christina Oatway, Marianne E Cuff, Jerzy Osipiuk, Karolina Michalska, Boguslaw P Nocek, Mikko Taipale, Alexei Savchenko, Alexander W Ensminger
Publikováno v:
Molecular Systems Biology, Vol 12, Iss 12, Pp 1-20 (2016)
Abstract Pathogens deliver complex arsenals of translocated effector proteins to host cells during infection, but the extent to which these proteins are regulated once inside the eukaryotic cell remains poorly defined. Among all bacterial pathogens,
Externí odkaz:
https://doaj.org/article/90c7ff684d7f4248a728c84036429cc9
Autor:
Anh Cao, Nouf Alluqmani, Fatima Hifza Mohammed Buhari, Laabiah Wasim, Logan K. Smith, Andrew T. Quaile, Michael Shannon, Zaki Hakim, Hossai Furmli, Dylan M. Owen, Alexei Savchenko, Bebhinn Treanor
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-18 (2018)
The galectin family of secreted lectins are important regulators of immune cell function; however, their role in B cell responses is poorly understood. Here, the authors identify IgM-BCR as a ligand for galectin-9. In resting naive cells, they show t
Externí odkaz:
https://doaj.org/article/4521a98af6a84e3a91478894d92db95c
Autor:
Dylan Valleau, Andrew T. Quaile, Hong Cui, Xiaohui Xu, Elena Evdokimova, Changsoo Chang, Marianne E. Cuff, Malene L. Urbanus, Scott Houliston, Cheryl H. Arrowsmith, Alexander W. Ensminger, Alexei Savchenko
Publikováno v:
Cell Reports, Vol 23, Iss 2, Pp 568-583 (2018)
Summary: Legionella pneumophila translocates the largest known arsenal of over 330 pathogenic factors, called “effectors,” into host cells during infection, enabling L. pneumophila to establish a replicative niche inside diverse amebas and human
Externí odkaz:
https://doaj.org/article/4a5302e8183f41a78230f4eb34018504
Autor:
William D. Gwynne, Yujin Suk, Stefan Custers, Nicholas Mikolajewicz, Jeremy K. Chan, Zsolt Zador, Shawn C. Chafe, Kui Zhai, Laura Escudero, Cunjie Zhang, Olga Zaslaver, Chirayu Chokshi, Muhammad Vaseem Shaikh, David Bakhshinyan, Ian Burns, Iqra Chaudhry, Omri Nachmani, Daniel Mobilio, William T. Maich, Patricia Mero, Kevin R. Brown, Andrew T. Quaile, Chitra Venugopal, Jason Moffat, J. Rafael Montenegro-Burke, Sheila K. Singh
Publikováno v:
Cancer cell. 40(12)
MYC-driven medulloblastoma (MB) is an aggressive pediatric brain tumor characterized by therapy resistance and disease recurrence. Here, we integrated data from unbiased genetic screening and metabolomic profiling to identify multiple cancer-selectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0234cd716b41da8132bba24ff35c66b
https://pubmed.ncbi.nlm.nih.gov/36368321
https://pubmed.ncbi.nlm.nih.gov/36368321
Autor:
Cheryl H. Arrowsmith, Andrew T. Quaile, Alexander Lemak, Alexei Savchenko, Dustin J. Little, Scott Houliston, Brian K. Coombes, Tatiana Skarina, Dylan Valleau, Rosa Di Leo, Dominika Borek
Publikováno v:
Proceedings of the National Academy of Sciences. 115:10004-10009
The pathogenic strategy of Escherichia coli and many other gram-negative pathogens relies on the translocation of a specific set of proteins, called effectors, into the eukaryotic host cell during infection. These effectors act in concert to modulate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b15f21f4082f8e6cd30b3b04aa30c603
https://doi.org/10.1073/pnas.1718350115
https://doi.org/10.1073/pnas.1718350115
Autor:
Alexei Savchenko, Fatima Hifza Mohammed Buhari, Andrew T. Quaile, Nouf Alluqmani, Zaki Hakim, Logan K. Smith, Michael Shannon, Hossai Furmli, Bebhinn Treanor, Laabiah Wasim, Anh Cao, Dylan M. Owen
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-18 (2018)
Cao, A, Alluqmani, N, Buhari, F H M, Wasim, L, Smith, L K, Quaile, A T, Shannon, M, Hakim, Z, Furmli, H, Owen, D M, Savchenko, A & Treanor, B 2018, ' Galectin-9 binds IgM-BCR to regulate B cell signaling ', Nature Communications, vol. 9, no. 1, 3288 . https://doi.org/10.1038/s41467-018-05771-8
Nature Communications
Cao, A, Alluqmani, N, Buhari, F H M, Wasim, L, Smith, L K, Quaile, A T, Shannon, M, Hakim, Z, Furmli, H, Owen, D M, Savchenko, A & Treanor, B 2018, ' Galectin-9 binds IgM-BCR to regulate B cell signaling ', Nature Communications, vol. 9, no. 1, 3288 . https://doi.org/10.1038/s41467-018-05771-8
Nature Communications
The galectin family of secreted lectins have emerged as important regulators of immune cell function; however, their role in B-cell responses is poorly understood. Here we identify IgM-BCR as a ligand for galectin-9. Furthermore, we show enhanced BCR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::341e404c5d9de1743a48de37615c97de
https://doaj.org/article/4521a98af6a84e3a91478894d92db95c
https://doaj.org/article/4521a98af6a84e3a91478894d92db95c
Autor:
Elena Evdokimova, Olga Egorova, Alexander F. Yakunin, Sergio G. Peisajovich, Boguslaw Nocek, Alexei Savchenko, Purnima S. Kompella, Andrew T. Quaile, Alexander W. Ensminger, Dylan Valleau, Peter J. Stogios
Publikováno v:
Journal of Biological Chemistry. 293:3307-3320
Host colonization by Gram-negative pathogens often involves delivery of bacterial proteins called “effectors” into the host cell. The pneumonia-causing pathogen Legionella pneumophila delivers more than 330 effectors into the host cell via its ty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e614aee7a7976f29245b5269fa35cc5
https://doi.org/10.1074/jbc.m117.812727
https://doi.org/10.1074/jbc.m117.812727
Autor:
Po Hsiang Wang, Burcu Şimşir, Yongchao Yin, Elizabeth A. Edwards, Abigail T. Farmer, Yi Yang, Shawn R. Campagna, Olivia Molenda, Nannan Jiang, Andrew T. Quaile, Allen K. Bourdon, Jun Yan, Frank E. Löffler, Meng Bi
Publikováno v:
Nature chemical biology
Cobamides such as vitamin B12 are structurally conserved, cobalt-containing tetrapyrrole biomolecules that have essential biochemical functions in all domains of life. In organohalide respiration, a vital biological process for the global cycling of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3e3aa1e01155752d9fef8ad416c6978
https://doi.org/10.1038/nchembio.2512
https://doi.org/10.1038/nchembio.2512
Publikováno v:
Applied and Environmental Microbiology. 82:40-50
The Dehalogenimonas population in a dechlorinating enrichment culture referred to as WBC-2 was previously shown to be responsible for trans -dichloroethene (tDCE) hydrogenolysis to vinyl chloride (VC). In this study, blue native polyacrylamide gel el
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66d75ee4f120b5a7a208c2374e8be0cb
https://doi.org/10.1128/aem.02017-15
https://doi.org/10.1128/aem.02017-15
Autor:
Dylan, Valleau, Dustin J, Little, Dominika, Borek, Tatiana, Skarina, Andrew T, Quaile, Rosa, Di Leo, Scott, Houliston, Alexander, Lemak, Cheryl H, Arrowsmith, Brian K, Coombes, Alexei, Savchenko
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 115(40)
The pathogenic strategy of Escherichia coli and many other gram-negative pathogens relies on the translocation of a specific set of proteins, called effectors, into the eukaryotic host cell during infection. These effectors act in concert to modulate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6122305173d2da0e4521e3f8431fa616
https://pubmed.ncbi.nlm.nih.gov/30217892
https://pubmed.ncbi.nlm.nih.gov/30217892