Zobrazeno 1 - 10
of 147
pro vyhledávání: '"Andrew T M Vaughan"'
Autor:
Yang Cui, Lili Qin, Jing Wu, Xuan Qu, Chen Hou, Wenyan Sun, Shiyong Li, Andrew T M Vaughan, Jian Jian Li, Jiankang Liu
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0129834 (2015)
SIRT3 is a key NAD+-dependent protein deacetylase in the mitochondria of mammalian cells, functioning to prevent cell aging and transformation via regulation of mitochondrial metabolic homeostasis. However, SIRT3 is also found to express in some huma
Externí odkaz:
https://doaj.org/article/654d60130bce45b19d34ab8fce3ef49e
Autor:
Robert C. Read, Alison R Hill, Andrew T M Vaughan, Diane Gbesemete, Muktar Ibrahim, Guy A. M. Berbers, Hans de Graaf, Anne-Marie Buisman, Andrew Gorringe, Kent E. Kester, Dimitri A. Diavatopoulos, Saul N. Faust, Andrew Preston
Publikováno v:
Clinical Infectious Diseases, 71, 2, pp. 403-411
Clinical Infectious Diseases
Clin Infect Dis
Clinical Infectious Diseases, 71, 403-411
Clinical Infectious Diseases
Clin Infect Dis
Clinical Infectious Diseases, 71, 403-411
Background Bordetella pertussis is among the leading causes of vaccine-preventable deaths and morbidity globally. Human asymptomatic carriage as a reservoir for community transmission of infections might be a target of future vaccine strategies, but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::505247258302b4dec841398f7d25f7b0
https://hdl.handle.net/2066/225112
https://hdl.handle.net/2066/225112
Autor:
Robert C. Read, Muktar Ibrahim, Hans de Graaf, Andrew Gorringe, Diane Gbesemete, Saul N. Faust, Andrew T M Vaughan, Jay R. Laver
Publikováno v:
BMJ Open
IntroductionNeisseria lactamicais a commensal organism found in the human nasopharynx and is closely related to the pathogenN. meningitidis(meningococcus). Carriage ofN. lactamicais associated with reduced meningococcal carriage and disease. We summa
Publikováno v:
The Journal of Immunology. 197:1587-1596
SHIP is an important regulator of immune cell signaling that functions to dephosphorylate the phosphoinositide phosphatidylinositol 3,4,5-trisphosphate at the plasma membrane and mediate protein–protein interactions. One established paradigm for SH
Publikováno v:
International Journal of Radiation Biology. 92:229-240
Purpose The rejoining of fragmented nuclear DNA caused by ionizing radiation may lead to lethal chromosome rearrangements, such as rings or dicentrics. The clinically useful linear quadratic relationship between dose and cell survival has been interp
Autor:
Lekh N. Dahal, Keith W. Chan, H.T. Claude Chan, Jinny H. Kim, Chie Yin Huang, Stephen A. Beers, Andrew T M Vaughan, Abbie Mead, Priyanka Narang, Juliet X. Bowater, Martin C. Taylor, Richard J. Stopforth, Francesco Forconi
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 201(4)
Rituximab is an anti-CD20 mAb used in the treatment of B cell malignancies. Loss of surface CD20 Ag from the surface of target cells is thought to be one mechanism governing resistance to rituximab, but how this occurs is not completely understood. T
Autor:
Demet Candas, Ralph R. Weichselbaum, J.M. Wang, Ming Fan, C.X. Pan, Gayle E. Woloschak, K. Lam, Arta M. Monjazeb, L. Liu, Lun-Quan Sun, David J. Grdina, C. Sweeney, S. Azgahdi, H. Chen, Y. Zhang, O. Ozpiskin, Andrew T M Vaughan, B. Xie, Jian Jian Li, William J. Murphy, S. Xia, L. Zhang
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 105:E39
Autor:
D. Gregory Farwell, Allen M. Chen, Andrew T M Vaughan, Megan E. Daly, Talia Zahra, Regina F Gandour-Edwards, Quang Luu
Publikováno v:
Head & Neck. 35:1652-1656
Background To report a single institutional experience with definitive radiation therapy alone for human papillomavirus (HPV)–positive head and neck cancer. Methods A total of 67 patients were treated by radiation therapy alone to a median dose of
Autor:
Demet Candas, Andrew T M Vaughan, Jeffrey S. Murley, Ming Fan, Jian Jian Li, Gayle E. Woloschak, Danupon Nantajit, David J. Grdina
Publikováno v:
Journal of Molecular Cell Biology. 5:166-175
Manganese superoxide dismutase (MnSOD), a major antioxidant enzyme within the mitochondria, is responsible for the detoxification of free radicals generated by cellular metabolism and environmental/therapeutic irradiation. Cell cycle-dependent kinase
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 740:34-42
Radiation treatment or chemotherapy has been linked with a higher risk of secondary cancers such as therapy related Acute Myeloid Leukemia (tAML). Several of these cancers have been shown to be correlated to the introduction of double stranded breaks