Zobrazeno 1 - 10
of 151
pro vyhledávání: '"Andrew T DeWan"'
Autor:
Tormod Rogne, Erik Solligård, Stephen Burgess, Ben M Brumpton, Julie Paulsen, Hallie C Prescott, Randi M Mohus, Lise T Gustad, Arne Mehl, Bjørn O Åsvold, Andrew T DeWan, Jan K Damås
Publikováno v:
PLoS Medicine, Vol 17, Iss 11, p e1003413 (2020)
BackgroundIn observational studies of the general population, higher body mass index (BMI) has been associated with increased incidence of and mortality from bloodstream infection (BSI) and sepsis. On the other hand, higher BMI has been observed to b
Externí odkaz:
https://doaj.org/article/4a02c39aa055441c856cafc338065b58
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0144114 (2015)
Asthmatics have an increased risk of being overweight/obese. Although the underlying mechanisms of this are unclear, genetic factors are believed to play an essential role. To identify common genetic variants that are associated with asthma-related B
Externí odkaz:
https://doaj.org/article/cb4ca6ff839f466ebf57d1097b2808a6
Autor:
Victoria L Patterson, Alfred J Zullo, Claire Koenig, Sean Stoessel, Hakryul Jo, Xinran Liu, Jinah Han, Murim Choi, Andrew T DeWan, Jean-Leon Thomas, Chia-Yi Kuan, Josephine Hoh
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e115789 (2014)
HTRA2, a serine protease in the intermembrane space, has important functions in mitochondrial stress signaling while its abnormal activity may contribute to the development of Parkinson's disease. Mice with a missense or null mutation of Htra2 fail t
Externí odkaz:
https://doaj.org/article/1e839ee060b74e1184e70e61f529d567
Autor:
Evgenya Y Popova, Xuming Xu, Andrew T DeWan, Anna C Salzberg, Arthur Berg, Josephine Hoh, Samuel S Zhang, Colin J Barnstable
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e46867 (2012)
The epigenetic contribution to neurogenesis is largely unknown. There is, however, growing evidence that posttranslational modification of histones is a dynamic process that shows many correlations with gene expression. Here we have followed the geno
Externí odkaz:
https://doaj.org/article/787870adfef1473ea71c1aedec947a7d
Autor:
Paola Sebastiani, Nadia Solovieff, Andrew T Dewan, Kyle M Walsh, Annibale Puca, Stephen W Hartley, Efthymia Melista, Stacy Andersen, Daniel A Dworkis, Jemma B Wilk, Richard H Myers, Martin H Steinberg, Monty Montano, Clinton T Baldwin, Josephine Hoh, Thomas T Perls
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e29848 (2012)
Like most complex phenotypes, exceptional longevity is thought to reflect a combined influence of environmental (e.g., lifestyle choices, where we live) and genetic factors. To explore the genetic contribution, we undertook a genome-wide association
Externí odkaz:
https://doaj.org/article/b1f6a912b0e84236b924f595f47ff04b
Autor:
Zicheng Li, Zuoheng Wang, Zhiyuan Chen, Heidi Voegeli, Judith H. Lichtman, Peter Smith, Ju Liu, Andrew T. DeWan, Josephine Hoh
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-26 (2023)
Abstract Background In light of previous studies that profiled breed-specific traits or used genome-wide association studies to refine loci associated with characteristic morphological features in dogs, the field has gained tremendous genetic insight
Externí odkaz:
https://doaj.org/article/c844a516b34548adac863b6003d8b45f
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-9 (2023)
Abstract Background Analysis of imputed genotypes is an important and routine component of genome-wide association studies and the increasing size of imputation reference panels has facilitated the ability to impute and test low-frequency variants fo
Externí odkaz:
https://doaj.org/article/c6e602e163224f069a6b3846ed7f9d2e
Autor:
Mayumi Hangai, Takahisa Kawaguchi, Masatoshi Takagi, Keitaro Matsuo, Soyoung Jeon, Charleston W.K. Chiang, Andrew T. Dewan, Adam J. de Smith, Toshihiko Imamura, Yasuhiro Okamoto, Akiko M. Saito, Takao Deguchi, Michiaki Kubo, Yoichi Tanaka, Yoko Ayukawa, Toshinari Hori, Kentaro Ohki, Nobutaka Kiyokawa, Takeshi Inukai, Yuki Arakawa, Makiko Mori, Daisuke Hasegawa, Daisuke Tomizawa, Hiroko Fukushima, Yuki Yuza, Yasushi Noguchi, Yuichi Taneyama, Setsuo Ota, Hiroaki Goto, Masakatsu Yanagimachi, Dai Keino, Kazutoshi Koike, Daisuke Toyama, Yozo Nakazawa, Kozue Nakamura, Koichi Moriwaki, Yujin Sekinaka, Daisuke Morita, Shinsuke Hirabayashi, Yosuke Hosoya, Yuri Yoshimoto, Hiroki Yoshihara, Miwa Ozawa, Shinobu Kobayashi, Naho Morisaki, Tshewang Gyeltshen, Osamu Takahashi, Yukinori Okada, Makiko Matsuda, Toshihiro Tanaka, Johji Inazawa, Junko Takita, Yasushi Ishida, Akira Ohara, Catherine Metayer, Joseph L. Wiemels, Xiaomei Ma, Shuki Mizutani, Katsuyoshi Koh, Yukihide Momozawa, Keizo Horibe, Fumihiko Matsuda, Motohiro Kato, Atsushi Manabe, Kevin Y. Urayama
Publikováno v:
Haematologica, Vol 109, Iss 4 (2023)
Externí odkaz:
https://doaj.org/article/33c9fce9f6da4bfcb04af4388d1b3ffd
Autor:
Andrew T. DeWan, Megan E. Cahill, Diana M. Cornejo-Sanchez, Yining Li, Zihan Dong, Tabassum Fabiha, Hao Sun, Gao Wang, Suzanne M. Leal
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Background: Asthma, type 2 diabetes (T2D), and anthropometric measures are correlated complex traits that all have a major genetic component.Objective: To investigate the overlap in genetic variants associated with these complex traits.Methods: Using
Externí odkaz:
https://doaj.org/article/0ed63eccfd5d4d77add40638f194591b
Autor:
Chung-Il Wi, Janneane F. Gent, Joshua T. Bublitz, Katherine S. King, Euijung Ryu, Keli Sorrentino, Julie Plano, Lisa McKay, Julie Porcher, Philip H. Wheeler, Sergio E. Chiarella, Andrew T. DeWan, Krystal J. Godri Pollitt, Beverley J. Sheares, Brian Leaderer, Young J. Juhn
Publikováno v:
Journal of Primary Care & Community Health, Vol 14 (2023)
Introduction: Nitrogen dioxide (NO 2 ) is known to be a trigger for asthma exacerbation. However, little is known about the role of seasonal variation in indoor and outdoor NO 2 levels in childhood asthma in a mixed rural-urban setting of North Ameri
Externí odkaz:
https://doaj.org/article/93a3c26394e64b6cae7872d0798d2420