Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Andrew T Crane"'
Autor:
Andrew T Crane, Matthew R Chrostek, Venkatramana D Krishna, Maple Shiao, Nikolas G Toman, Clairice M Pearce, Sarah K Tran, Christopher J Sipe, Winston Guo, Joseph P Voth, Shivanshi Vaid, Hui Xie, Wei-Cheng Lu, Will Swanson, Andrew W Grande, Mark R Schleiss, Craig J Bierle, Maxim C-J Cheeran, Walter C Low
Publikováno v:
PLoS ONE, Vol 15, Iss 10, p e0232858 (2020)
Zika virus (ZIKV) exhibits a tropism for brain tumor cells and has been used as an oncolytic virus to target brain tumors in mice with modest effects on extending median survival. Recent studies have highlighted the potential for combining virotherap
Externí odkaz:
https://doaj.org/article/706b7e594e0242e88081ab6d357ff89b
Autor:
Andrew T. Crane, Rajagopal N. Aravalli, Atsushi Asakura, Andrew W. Grande, Venkatramana D. Krishna, Daniel F. Carlson, Maxim C.-J. Cheeran, Georgette Danczyk, James R. Dutton, Perry B. Hackett, Wei-Shou Hu, Ling Li, Wei-Cheng Lu, Zachary D. Miller, Timothy D. O’Brien, Angela Panoskaltsis-Mortari, Ann M. Parr, Clairice Pearce, Mercedes Ruiz-Estevez, Maple Shiao, Christopher J. Sipe, Nikolas G. Toman, Joseph Voth, Hui Xie, Clifford J. Steer, Walter C. Low
Publikováno v:
Cell Transplantation, Vol 28 (2019)
Blastocyst complementation combined with gene editing is an emerging approach in the field of regenerative medicine that could potentially solve the worldwide problem of organ shortages for transplantation. In theory, blastocyst complementation can g
Externí odkaz:
https://doaj.org/article/0e597a7add9c43cfb591e8698243ec66
Autor:
Maple L. Shiao, Ce Yuan, Andrew T. Crane, Joseph P. Voth, Mario Juliano, Laura L. Hocum Stone, Zhenghong Nan, Ying Zhang, Nicole Kuzmin-Nichols, Paul R. Sanberg, Andrew W. Grande, Walter C. Low
Publikováno v:
Cell Transplantation, Vol 28 (2019)
Our group previously demonstrated that administration of a CD34-negative fraction of human non- hematopoietic umbilical cord blood stem cells (UCBSC) 48 h after ischemic injury could reduce infarct volume by 50% as well as significantly ameliorate ne
Externí odkaz:
https://doaj.org/article/6dc8624213974441a96a7994b986a1fa
Autor:
Kanut Laoharawee, Matthew J. Johnson, Walker S. Lahr, Christopher J. Sipe, Evan Kleinboehl, Joseph J. Peterson, Cara-lin Lonetree, Jason B. Bell, Nicholas J. Slipek, Andrew T. Crane, Beau R. Webber, Branden S. Moriarity
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 17; Pages: 9749
Monocytes and their downstream effectors are critical components of the innate immune system. Monocytes are equipped with chemokine receptors, allowing them to migrate to various tissues, where they can differentiate into macrophage and dendritic cel
Publikováno v:
Brain Sciences, Vol 4, Iss 1, Pp 202-219 (2014)
Transplantation of stem cells for the treatment of Huntington’s disease (HD) garnered much attention prior to the turn of the century. Several studies using mesenchymal stem cells (MSCs) have indicated that these cells have enormous therapeutic pot
Externí odkaz:
https://doaj.org/article/49485c08dceb4489af2d62d697ae5c29
Autor:
Matthew R. Chrostek, Emily G. Fellows, Winston L. Guo, William J. Swanson, Andrew T. Crane, Maxim C. Cheeran, Walter C. Low, Andrew W. Grande
Publikováno v:
Brain Sciences, Vol 9, Iss 10, p 270 (2019)
Traumatic brain injuries (TBIs) are a leading cause of death and disability. Additionally, growing evidence suggests a link between TBI-induced neuroinflammation and neurodegenerative disorders. Treatments for TBI patients are limited, largely focuse
Externí odkaz:
https://doaj.org/article/f5c231b7946944df9a09a83c2a626b61
Autor:
Andrew T. Crane, Taichi Hatta, Walter C. Low, Joseph P. Voth, Jennifer L. Brown, Mercedes Ruiz-Estévez, Warren Cormack, Tsutomu Sawai, Francis X. Shen, Misao Fujita
Publikováno v:
Stem Cell Reports
Summary We report findings from a new survey of US public attitudes toward human-animal chimeric embryo (HACE) research, designed to compare with recently reported Japanese survey data. We find that 59% of the US public can personally accept the proc
Publikováno v:
Hepatic Medicine: Evidence and Research. 12:15-27
Background Primary human hepatocytes (PHHs) are the ideal candidates for studying critical liver functions such as drug metabolism and toxicity. However, as they are isolated from discarded livers that are unsuitable for transplantation, they possess
Autor:
Maple Shiao, Kevin Liaw, Huihui Kuang, Matthew R. Chrostek, Andrew T. Crane, Michael A. Harris, Efrosini Kokkoli, M. Gerard O'Sullivan, Walter C. Low, Lucy Lin, Beibei Xu, Thomas Pengo, Rangaramanujam M. Kannan, Zachary Schneiderman, Clark C. Chen, Alexandru-Flaviu Tabaran
Publikováno v:
Science Advances
Description
DNA nanotubes can cross blood-brain tumor barrier and enhance survival with no toxicity when used for the local delivery of DOX.
Effective treatment of glioblastoma remains a daunting challenge. One of the major hurdles in the d
DNA nanotubes can cross blood-brain tumor barrier and enhance survival with no toxicity when used for the local delivery of DOX.
Effective treatment of glioblastoma remains a daunting challenge. One of the major hurdles in the d
Autor:
Mercedes Ruiz-Estévez, Christopher J. Sipe, Wei Shou Hu, Ling Li, Nikolas G. Toman, Andrew W. Grande, Clairice Pearce, Daniel F. Carlson, Ann M. Parr, Timothy O'Brien, Georgette Danczyk, James R. Dutton, Joseph P. Voth, Walter C. Low, Maxim C.-J. Cheeran, Zachary D. Miller, Angela Panoskaltsis-Mortari, Clifford J. Steer, Venkatramana D. Krishna, Andrew T. Crane, Perry B. Hackett, Wei Cheng Lu, Hui Xie, Atsushi Asakura, Rajagopal N. Aravalli, Maple Shiao
Publikováno v:
Cell Transplantation
Cell Transplantation, Vol 28 (2019)
Cell Transplantation, Vol 28 (2019)
Blastocyst complementation combined with gene editing is an emerging approach in the field of regenerative medicine that could potentially solve the worldwide problem of organ shortages for transplantation. In theory, blastocyst complementation can g