Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Andrew Stiegler"'
Systemic administration of choline acetyltransferase decreases blood pressure in murine hypertension
Autor:
Andrew Stiegler, Jian-Hua Li, Vivek Shah, Tea Tsaava, Aisling Tynan, Huan Yang, Yehuda Tamari, Michael Brines, Kevin J. Tracey, Sangeeta S. Chavan
Publikováno v:
Molecular Medicine, Vol 27, Iss 1, Pp 1-12 (2021)
Abstract Acetylcholine (ACh) decreases blood pressure by stimulating endothelium nitric oxide-dependent vasodilation in resistance arterioles. Normal plasma contains choline acetyltransferase (ChAT) and its biosynthetic product ACh at appreciable con
Externí odkaz:
https://doaj.org/article/de421aefc6ae4f1a93e2a0bcae9ebfc3
Autor:
Harold A. Silverman, Andrew Stiegler, Téa Tsaava, Justin Newman, Benjamin E. Steinberg, Emily Battinelli Masi, Sergio Robbiati, Chad Bouton, Patricio T. Huerta, Sangeeta S. Chavan, Kevin J. Tracey
Publikováno v:
Bioelectronic Medicine, Vol 4, Iss 1, Pp 1-13 (2018)
Abstract Background The vagus nerve plays an important role in the regulation of organ function, including reflex pathways that regulate immunity and inflammation. Recent studies using genetically modified mice have improved our understanding of mole
Externí odkaz:
https://doaj.org/article/eff1c9bddb264f14aa5d096d268bfa09
Autor:
Benjamin E. Steinberg, Harold A. Silverman, Sergio Robbiati, Manoj K. Gunasekaran, Téa Tsaava, Emily Battinelli, Andrew Stiegler, Chad E. Bouton, Sangeeta S. Chavan, Kevin J. Tracey, Patricio T. Huerta
Publikováno v:
Bioelectronic Medicine, Vol 3, Iss 1, Pp 7-17 (2016)
Abstract The axons of the sensory, or afferent, vagus nerve transmit action potentials to the central nervous system in response to changes in the body’s metabolic and physiological status. Recent advances in identifying neural circuits that regula
Externí odkaz:
https://doaj.org/article/82e7f528c9314d10b323e8a3723b5551
Autor:
Zhongliang Ju, Sangeeta S Chavan, Daniel J Antoine, Meghan Dancho, Teá Tsaava, Jianhua Li, Ben Lu, Yaakov A Levine, Andrew Stiegler, Yehuda Tamari, Yousef Al-Abed, Jesse Roth, Kevin J Tracey, Huan Yang
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e103992 (2014)
Inflammatory bowel disease (IBD) is chronic inflammation of the gastrointestinal tract that affects millions of people worldwide. Although the etiology of IBD is not clear, it is known that products from stressed cells and enteric microbes promote in
Externí odkaz:
https://doaj.org/article/9e7610d3a8a0427284075b90bfcba6cf
Systemic administration of choline acetyltransferase decreases blood pressure in murine hypertension
Autor:
Aisling Tynan, Andrew Stiegler, Jianhua Li, Sangeeta S. Chavan, Tea Tsaava, Michael Brines, Kevin J. Tracey, Yehuda Tamari, Huan Yang, Vivek Shah
Publikováno v:
Molecular Medicine, Vol 27, Iss 1, Pp 1-12 (2021)
Molecular Medicine
Molecular Medicine
Acetylcholine (ACh) decreases blood pressure by stimulating endothelium nitric oxide-dependent vasodilation in resistance arterioles. Normal plasma contains choline acetyltransferase (ChAT) and its biosynthetic product ACh at appreciable concentratio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0fdc0d112109782916175aaf2c9c8f2
https://doaj.org/article/de421aefc6ae4f1a93e2a0bcae9ebfc3
https://doaj.org/article/de421aefc6ae4f1a93e2a0bcae9ebfc3
Autor:
Sangeeta S. Chavan, Vivek Shah, Jian-Hua Li, Kevin J. Tracey, Aisling Tynan, Andrew Stiegler, Tea Tsaava, Yehuda Tamari
Publikováno v:
The FASEB Journal. 35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2a7e97ab3e91304dc2978ed58d78918
https://doi.org/10.1096/fasebj.2021.35.s1.04623
https://doi.org/10.1096/fasebj.2021.35.s1.04623
Autor:
Manojkumar Gunasekaran, Eric H. Chang, Kevin J. Tracey, Qing Chang, Valentin A. Pavlov, Sangeeta S. Chavan, Jianhua Li, Meghan E. Addorisio, Adam M. Kressel, Tea Tsaava, Andrew Stiegler, Ulf Andersson, Harold A. Silverman, Tomás S. Huerta
Survival of an organism requires mechanisms to sense damaging factors in the environment. In mammals, bacterial toxins and inflammatory mediators stimulate nociceptive sensory neurons to activate protective reflexes. Whereas the vagus nerve reflex ci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99d4e595a4a65c2e17e04efff729effe
https://doi.org/10.1101/822734
https://doi.org/10.1101/822734
Autor:
Tea Tsaava, Sangeeta S. Chavan, Benjamin E. Steinberg, Harold A. Silverman, Emily Battinelli, Manojkumar Gunasekaran, Sergio Robbiati, Chad E. Bouton, Kevin J. Tracey, Patricio T. Huerta, Andrew Stiegler
Publikováno v:
Bioelectronic Medicine, Vol 3, Iss 1, Pp 7-17 (2016)
The axons of the sensory, or afferent, vagus nerve transmit action potentials to the central nervous system in response to changes in the body’s metabolic and physiological status. Recent advances in identifying neural circuits that regulate immune
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72716d71d86bbc7a7ef58a818f98dcd9
https://doi.org/10.15424/bioelectronmed.2016.00007
https://doi.org/10.15424/bioelectronmed.2016.00007
Autor:
Chad E. Bouton, Benjamin E. Steinberg, Sergio Robbiati, Tea Tsaava, Kevin J. Tracey, Patricio T. Huerta, Emily Battinelli Masi, Justin Newman, Andrew Stiegler, Harold A. Silverman, Sangeeta S. Chavan
Publikováno v:
Bioelectronic Medicine
Bioelectronic Medicine, Vol 4, Iss 1, Pp 1-13 (2018)
Bioelectronic Medicine, Vol 4, Iss 1, Pp 1-13 (2018)
Background The vagus nerve plays an important role in the regulation of organ function, including reflex pathways that regulate immunity and inflammation. Recent studies using genetically modified mice have improved our understanding of molecular mec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccb78fdb858aae20e66bd2780981d16c
https://pubmed.ncbi.nlm.nih.gov/32232079
https://pubmed.ncbi.nlm.nih.gov/32232079
Autor:
Harold A. Silverman, Meghan Addorisio, Tea Tsaava, Andrew Stiegler, Adam M. Kressel, Christopher A. Chin, Manojkumar Gunasekaran, Valentin A. Pavlov, Sangeeta S. Chavan, Kevin J. Tracey
Publikováno v:
The Journal of Immunology. 200:170.27-170.27
The vagus nerve plays an important role in maintaining an organism’s immune homeostasis through the inflammatory reflex. Inflammatory molecules including LPS, TNF and IL-1β can mediate electrophysiological changes in vagus nerve signaling. Reasoni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a3d9bfafb3ecd80ca91bfaaf1bc4f32c
https://doi.org/10.4049/jimmunol.200.supp.170.27
https://doi.org/10.4049/jimmunol.200.supp.170.27