Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Andrew Stalker"'
Autor:
Frederic St‐Denis‐Bissonnette, Shirley Qiu, Sarah E. Cummings, Melanie Kirkby, Yohannes Haile, Sarah Wassmer, Gauri Muradia, Jelica Mehic, Andrew Stalker, Amit Shrestha, Michele Ardolino, Seung‐Hwan Lee, Dylan Burger, Lisheng Wang, Jessie R. Lavoie
Publikováno v:
Journal of Extracellular Biology, Vol 3, Iss 7, Pp n/a-n/a (2024)
Abstract Natural killer cell‐derived extracellular vesicles (NK‐EVs) are candidate biotherapeutics against various cancers. However, standardised potency assays are necessary for a reliable assessment of NK‐EVs' cytotoxicity. This study aims to
Externí odkaz:
https://doaj.org/article/e9c74a4ae6444282ad687844f70ffab3
Autor:
Sarah E. Cummings, Sean P. Delaney, Frederic St-Denis Bissonnette, Andrew Stalker, Gauri Muradia, Jelica Mehic, Tyson E. Graber, Tommy Alain, Jessie R. Lavoie
Publikováno v:
iScience, Vol 27, Iss 1, Pp 108708- (2024)
Summary: Extracellular vesicles (EVs) are entering the clinical arena as novel biologics for infectious diseases, potentially serving as the immunogenic components of next generation vaccines. However, relevant human assays to evaluate the immunogeni
Externí odkaz:
https://doaj.org/article/46998e4c994a4f13a53d86c66f5bea2f
Autor:
Frederic St‐Denis‐Bissonnette, Sarah E. Cummings, Shirley Qiu, Andrew Stalker, Gauri Muradia, Jelica Mehic, Karan Mediratta, Shelby Kaczmarek, Dylan Burger, Seung‐Hwan Lee, Lisheng Wang, Jessie R. Lavoie
Publikováno v:
Journal of Extracellular Vesicles, Vol 12, Iss 12, Pp n/a-n/a (2023)
Abstract Natural killer cell‐derived extracellular vesicles (NK‐EVs) have shown promising potential as biotherapeutics for cancer due to their unique attributes as cytotoxic nanovesicles against cancer cells and immune‐modulatory activity towar
Externí odkaz:
https://doaj.org/article/1906ed4190454e6db53b02b8e2e4579a
Autor:
Grayson Hatfield, Lioudmila Tepliakova, Genevieve Gingras, Andrew Stalker, Xuguang Li, Yves Aubin, Roger Y. Tam
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Monoclonal antibodies (mAbs) comprise an essential type of biologic therapeutics and are used to treat diseases because of their anti-cancer and anti-inflammatory properties, and their ability to protect against respiratory infections. Its production
Externí odkaz:
https://doaj.org/article/c2390b51eba64c2492d1927ed94ccfb6
Autor:
Jonathan Gobin, Gauri Muradia, Jelica Mehic, Carole Westwood, Lauren Couvrette, Andrew Stalker, Stewart Bigelow, Christian C. Luebbert, Frédéric St-Denis Bissonnette, Michael J. W. Johnston, Simon Sauvé, Roger Y. Tam, Lisheng Wang, Michael Rosu-Myles, Jessie R. Lavoie
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-20 (2021)
Abstract Background Extracellular vesicles (EVs) produced by human bone marrow-derived mesenchymal stromal cells (hBM-MSCs) are currently investigated for their clinical effectiveness towards immune-mediated diseases. The large amounts of stem cell-d
Externí odkaz:
https://doaj.org/article/a55f2bdc68d84265a2f18242fd0f7540
Autor:
Afnan Munshi, Jelica Mehic, Marybeth Creskey, Jonathan Gobin, Jun Gao, Emma Rigg, Gauri Muradia, Christian C. Luebbert, Carole Westwood, Andrew Stalker, David S. Allan, Michael J. W. Johnston, Terry Cyr, Michael Rosu-Myles, Jessie R. Lavoie
Publikováno v:
Stem Cell Research & Therapy, Vol 10, Iss 1, Pp 1-18 (2019)
Abstract Background Clinical applications have shown extracellular vesicles (EVs) to be a major paracrine effector in therapeutic responses produced by human mesenchymal stromal/stem cells (hMSCs). As the regenerative capacity of EVs is mainly ascrib
Externí odkaz:
https://doaj.org/article/699ae8e7d7ea4864b8c63797fe386e89
Autor:
Simon Sauvé, Andrew Stalker, Michael Rosu-Myles, Jonathan Gobin, Christian C. Luebbert, Michael V. Johnston, Lisheng Wang, Jessie R. Lavoie, Roger Y. Tam, Carole Westwood, Jelica Mehic, Stewart Bigelow, Gauri Muradia, Frédéric St-Denis Bissonnette, Lauren Couvrette
Publikováno v:
Stem Cell Research & Therapy
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-20 (2021)
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-20 (2021)
Background Extracellular vesicles (EVs) produced by human bone marrow-derived mesenchymal stromal cells (hBM-MSCs) are currently investigated for their clinical effectiveness towards immune-mediated diseases. The large amounts of stem cell-derived EV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::113b73b201fb56586ef87abc59d6aec7
https://doi.org/10.1186/s13287-021-02190-3
https://doi.org/10.1186/s13287-021-02190-3
Publikováno v:
Talanta. 222
Many methods have been reported to detect Cryptosporidium parvum (C. parvum) oocysts in the water environment using monoclonal antibodies. Herein, we report the use of DNA aptamers as an alternative ligand. We present the highly sensitive detection o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ca4a0d244858f4719e66c03d3a2cfeb
https://pubmed.ncbi.nlm.nih.gov/33167272
https://pubmed.ncbi.nlm.nih.gov/33167272
Publikováno v:
Environmental Toxicology and Pharmacology. 86:103662
Although considerable inter-individual variability exists in health effects associated with air pollutant exposure, underlying reasons remain unclear. We examined whether innate differences in stress axis function modify lung glucocorticoid and macro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dd466693b9c06e2e82b65f7237f897b
https://doi.org/10.1016/j.etap.2021.103662
https://doi.org/10.1016/j.etap.2021.103662
Autor:
Aida, Sivro, Alexandra, Schuetz, Daniel, Sheward, Vineet, Joag, Sergey, Yegorov, Lenine J, Liebenberg, Nonhlanhla, Yende-Zuma, Andrew, Stalker, Ruth S, Mwatelah, Philippe, Selhorst, Nigel, Garrett, Natasha, Samsunder, Anisha, Balgobin, Fatima, Nawaz, Claudia, Cicala, James, Arthos, Anthony S, Fauci, Aggrey Omu, Anzala, Joshua, Kimani, Bernard S, Bagaya, Noah, Kiwanuka, Carolyn, Williamson, Rupert, Kaul, Jo-Ann S, Passmore, Nittaya, Phanuphak, Jintanat, Ananworanich, Aftab, Ansari, Quarraisha, Abdool Karim, Salim S, Abdool Karim, Lyle R, McKinnon
Publikováno v:
Science translational medicine. 10(425)
The gastrointestinal (GI) mucosa is central to HIV pathogenesis, and the integrin α(4)β(7) promotes the homing of immune cells to this site. Data from SIV animal models suggest that α(4)β(7) blockade provides prophylactic and therapeutic benefits
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::327075ba5aaf62d493169b6a723695a0
https://pubmed.ncbi.nlm.nih.gov/29367348
https://pubmed.ncbi.nlm.nih.gov/29367348