Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Andrew Soper"'
Autor:
Lijun Ling, Manse Kim, Andrew Soper, Martina Kovarova, Rae Ann Spagnuolo, Nurjahan Begum, Jennifer Kirchherr, Nancie Archin, Diana Battaglia, Dave Cleveland, Angela Wahl, David M. Margolis, Edward P. Browne, J. Victor Garcia
Publikováno v:
mBio, Vol 15, Iss 9 (2024)
ABSTRACT The HIV reservoir is more dynamic than previously thought with around 70% of the latent reservoir originating from viruses circulating within 1 year of the initiation of antiretroviral therapy (ART). In an ex vivo model system of HIV latency
Externí odkaz:
https://doaj.org/article/11242e5bc7854ce8b4f92e9d3644d4a7
Autor:
Vanessa M. Howieson, Joy Zeng, Joachim Kloehn, Christina Spry, Chiara Marchetti, Matteo Lunghi, Emmanuel Varesio, Andrew Soper, Anthony G. Coyne, Chris Abell, Giel G. van Dooren, Kevin J. Saliba
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 22, Iss , Pp 1-8 (2023)
Toxoplasma gondii is a pervasive apicomplexan parasite that can cause severe disease and death in immunocompromised individuals and the developing foetus. The treatment of toxoplasmosis often leads to serious side effects and novel drugs and drug tar
Externí odkaz:
https://doaj.org/article/00b024bbf99f4341a185721a0ef4505e
Autor:
Yusuke Nakano, Keisuke Yamamoto, Mahoko Takahashi Ueda, Andrew Soper, Yoriyuki Konno, Izumi Kimura, Keiya Uriu, Ryuichi Kumata, Hirofumi Aso, Naoko Misawa, Shumpei Nagaoka, Soma Shimizu, Keito Mitsumune, Yusuke Kosugi, Guillermo Juarez-Fernandez, Jumpei Ito, So Nakagawa, Terumasa Ikeda, Yoshio Koyanagi, Reuben S Harris, Kei Sato
Publikováno v:
PLoS Pathogens, Vol 16, Iss 9, p e1008812 (2020)
The APOBEC3 deaminases are potent inhibitors of virus replication and barriers to cross-species transmission. For simian immunodeficiency virus (SIV) to transmit to a new primate host, as happened multiple times to seed the ongoing HIV-1 epidemic, th
Externí odkaz:
https://doaj.org/article/d550843508e54cdeb238ee8a7ee1d1a4
Autor:
Yusuke Nakano, Hirofumi Aso, Andrew Soper, Eri Yamada, Miyu Moriwaki, Guillermo Juarez-Fernandez, Yoshio Koyanagi, Kei Sato
Publikováno v:
Retrovirology, Vol 14, Iss 1, Pp 1-12 (2017)
Abstract Apolipoprotein B mRNA editing enzyme catalytic polypeptide-like 3 (APOBEC3) proteins are mammalian-specific cellular deaminases and have a robust ability to restrain lentivirus replication. To antagonize APOBEC3-mediated antiviral action, le
Externí odkaz:
https://doaj.org/article/dd78050a680e415cb625feaf9c1ea460
Autor:
Andrew Soper, Izumi Kimura, Shumpei Nagaoka, Yoriyuki Konno, Keisuke Yamamoto, Yoshio Koyanagi, Kei Sato
Publikováno v:
Frontiers in Immunology, Vol 8 (2018)
Human immunodeficiency virus type 1 (HIV-1) is the causative agent of acquired immunodeficiency syndrome and its infection leads to the onset of several disorders such as the depletion of peripheral CD4+ T cells and immune activation. HIV-1 is recogn
Externí odkaz:
https://doaj.org/article/93daa672be2d49a9844d33a219871d37
Autor:
Yusuke Nakano, Naoko Misawa, Guillermo Juarez-Fernandez, Miyu Moriwaki, Shinji Nakaoka, Takaaki Funo, Eri Yamada, Andrew Soper, Rokusuke Yoshikawa, Diako Ebrahimi, Yuuya Tachiki, Shingo Iwami, Reuben S Harris, Yoshio Koyanagi, Kei Sato
Publikováno v:
PLoS Pathogens, Vol 13, Iss 9, p e1006606 (2017)
[This corrects the article DOI: 10.1371/journal.ppat.1006348.].
Externí odkaz:
https://doaj.org/article/9a67a926bfce460fbe06094713bfc77e
Autor:
Yusuke Nakano, Naoko Misawa, Guillermo Juarez-Fernandez, Miyu Moriwaki, Shinji Nakaoka, Takaaki Funo, Eri Yamada, Andrew Soper, Rokusuke Yoshikawa, Diako Ebrahimi, Yuuya Tachiki, Shingo Iwami, Reuben S Harris, Yoshio Koyanagi, Kei Sato
Publikováno v:
PLoS Pathogens, Vol 13, Iss 5, p e1006348 (2017)
APOBEC3 (A3) family proteins are DNA cytosine deaminases recognized for contributing to HIV-1 restriction and mutation. Prior studies have demonstrated that A3D, A3F, and A3G enzymes elicit a robust anti-HIV-1 effect in cell cultures and in humanized
Externí odkaz:
https://doaj.org/article/fd904721000f45729656d8294af3f0d8
Publikováno v:
Microbiology and immunologyREFERENCES. 65(1)
The appearance of human immunodeficiency virus type 1 (HIV-1) plasma viremia is associated with progression to symptomatic disease and CD4+ T cell depletion. To locate the source of systemic viremia, this study employed a novel method to trace HIV-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::114c3d4b7b53ec83169033cc404e431a
https://pubmed.ncbi.nlm.nih.gov/33230872
https://pubmed.ncbi.nlm.nih.gov/33230872
Autor:
Kei Sato, Mahoko Takahashi Ueda, Keiya Uriu, Yusuke Kosugi, Reuben S. Harris, Yusuke Nakano, Yoshio Koyanagi, Shumpei Nagaoka, Hirofumi Aso, Keito Mitsumune, Yoriyuki Konno, Andrew Soper, Jumpei Ito, Naoko Misawa, So Nakagawa, Izumi Kimura, Terumasa Ikeda, Keisuke Yamamoto, Soma Shimizu, Guillermo Juarez-Fernandez, Ryuichi Kumata
Publikováno v:
PLoS Pathogens, Vol 16, Iss 9, p e1008812 (2020)
PLoS Pathogens
PLoS Pathogens
The APOBEC3 deaminases are potent inhibitors of virus replication and barriers to cross-species transmission. For simian immunodeficiency virus (SIV) to transmit to a new primate host, as happened multiple times to seed the ongoing HIV-1 epidemic, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a7f5977503972d44ac8fd8a588db771
https://doaj.org/article/d550843508e54cdeb238ee8a7ee1d1a4
https://doaj.org/article/d550843508e54cdeb238ee8a7ee1d1a4
Autor:
Hirofumi Nakaoka, Priscilla Turelli, Andrew Soper, Alexandre Coudray, Izumi Kimura, Jumpei Ito, Yoshio Koyanagi, Didier Trono, Kei Sato, Ituro Inoue
Numerous genes are aberrantly expressed in tumors, but its cause remains unclear. Human endogenous retroviruses (HERVs) are repetitive elements in the genome and have a potential to work as enhancers modulating adjacent genes. Since numerous HERVs ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7879bdee889b820d3e0ee0b4060c9e1e
https://doi.org/10.1101/2020.02.02.931501
https://doi.org/10.1101/2020.02.02.931501
