Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Andrew Slee"'
Autor:
David W. Hogg, Andrea L. Reid, Thomas L. Dodsworth, Yani Chen, Ross M. Reid, Mei Xu, Mia Husic, Peggy R. Biga, Andrew Slee, Leslie T. Buck, Dalia Barsyte-Lovejoy, Marius Locke, David A. Lovejoy
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Skeletal muscle regulation is responsible for voluntary muscular movement in vertebrates. The genes of two essential proteins, teneurins and latrophilins (LPHN), evolving in ancestors of multicellular animals form a ligand-receptor pair, and are now
Externí odkaz:
https://doaj.org/article/075dc888e57640939d361dc8d39d5494
Autor:
Andrew Slee, James Shanahan, Bradley Carver, Adam Nir, Peter Cornelius, Benjamin Mayes, Sara Little, Nir Raphael
Publikováno v:
Cancer Research. 80:P3-11
Mutations in the PI3K pathway have been observed in about 40% of ER+/Her2- breast cancer patients. Amplification as well as mutation of the catalytic p110α subunit of PI3K results in activation of this pathway within tumors, conferring a growth adva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47c8eb04d5dad70aa8785198cca92fac
https://doi.org/10.1158/1538-7445.sabcs19-p3-11-13
https://doi.org/10.1158/1538-7445.sabcs19-p3-11-13
Autor:
Olga Udartseva, Malgorzata Pupecka-Swider, Pilar Garcia-Broncano, Naxin Guo, Spencer Campbell, Elizabeth Klakus, Rebecca Ward, Priyadarshini Iyer, Christine Brittsan, Beth Wensley, Benjamin Morin, Andrew Slee, Dhan Chand, Claire Galand, Olga Ignatovich, Emmanuel Briend, David Savitsky
Publikováno v:
Cancer Research. 82:2906-2906
Background: Ig-Like Transcript 2 (ILT2, LILRB1) is an inhibitory receptor prominently expressed on resting macrophages, monocytes, and dendritic cells (DCs), with variable expression on CD4+ T cells, CD8+ T cells, B cells, NK cells, and NKT cells in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19a2d21317a8d108ad0a20adc35b2bc9
https://doi.org/10.1158/1538-7445.am2022-2906
https://doi.org/10.1158/1538-7445.am2022-2906
Autor:
Adam Nir, Benjamin Mayes, Nir Raphael, Bradley Carver, Peter Cornelius, Sara Little, Andrew Slee, Pierre Dufour, James Shanahan
Publikováno v:
Cancer Research. 81:1068-1068
Small molecule MetAP2 inhibitor TNP-470 previously showed clinical anti-tumor activity, however CNS side effects and poor drug-like properties limited its development. SDX-7320 is a polymer-drug conjugate of a novel MetAP2 inhibitor (SDX-7539), inten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dedc8be0e478169de40906631fc23fb1
https://doi.org/10.1158/1538-7445.am2021-1068
https://doi.org/10.1158/1538-7445.am2021-1068
Autor:
Peter Cornelius, James Shanahan, Bradley Carver, Sara Little, David J. Turnquist, Andrew Slee, Benjamin Mayes
Publikováno v:
Cancer Research. 79:1226-1226
Obese patients with certain cancers face a greater risk of dying from their cancer compared to non-obese patients. Obesity may contribute to cancer progression via multiple mechanisms: increased leptin, decreased adiponectin, increased adipose tissue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2d24cfeb04d3e1c74e81291b9ab8ecf
https://doi.org/10.1158/1538-7445.am2019-1226
https://doi.org/10.1158/1538-7445.am2019-1226
Abstract 4919: Preclinical activity of SDX-7320 in mouse models of obesity and obesity-driven cancer
Autor:
Andrew Slee, Bradley Carver, Benjamin Mayes, Peter Cornelius, Alfred Anderson-Villaluz, James Shanahan, Robert J. Lutz, Petersen John S, David J. Turnquist, Sara Little, Kimberly Sullivan
Publikováno v:
Cancer Research. 78:4919-4919
Cancer patients who are obese face a greater risk of dying from cancer compared to nonobese patients (Calle, 2003). Obesity is believed to contribute to metastasis and progression of cancer via multiple mechanisms: increased secretion of the adipose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d36aa290c5ac9ac7c85694de67f0acb
https://doi.org/10.1158/1538-7445.am2018-4919
https://doi.org/10.1158/1538-7445.am2018-4919