Výsledky vyhledávání - "Andrew Sewell"

Akademický článek

Structure-guided engineering of immunotherapies targeting TRBC1 and TRBC2 in T cell malignancies

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)

Abstract Peripheral T cell lymphomas are typically aggressive with a poor prognosis. Unlike other hematologic malignancies, the lack of target antigens to discriminate healthy from malignant cells limits the efficacy of immunotherapeutic approaches.

Externí odkaz: https://doaj.org/article/0a0cba1c19b24f4e8e75069f7a2b0924

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Akademický článek

Navigation-Guided Transnasal Endoscopic Delineation of the Posterior Margin for Maxillary Sinus Cancers: A Preclinical Study

Autor: Stefano Taboni, Marco Ferrari, Michael J. Daly, Harley H. L. Chan, Donovan Eu, Tommaso Gualtieri, Ashok R. Jethwa, Axel Sahovaler, Andrew Sewell, Wael Hasan, Ilyes Berania, Jimmy Qiu, John de Almeida, Piero Nicolai, Ralph W. Gilbert, Jonathan C. Irish

Publikováno v: Frontiers in Oncology, Vol 11 (2021)

BackgroundThe resection of advanced maxillary sinus cancers can be challenging due to the anatomical proximity to surrounding critical anatomical structures. Transnasal endoscopy can effectively aid the delineation of the posterior margin of resectio

Externí odkaz: https://doaj.org/article/e2248754c77247fcbcc5bc3a65efeb20

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Akademický článek

Editorial: L2 Phonology Meets L2 Pronunciation

Autor: John Archibald, Mary Grantham O’Brien, Andrew Sewell

Publikováno v: Frontiers in Communication, Vol 6 (2021)

Externí odkaz: https://doaj.org/article/26f161093c4e4163ac86123627a1c049

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Akademický článek

Functional Load and the Teaching-Learning Relationship in L2 Pronunciation

Autor: Andrew Sewell

Publikováno v: Frontiers in Communication, Vol 6 (2021)

Though frequent recourse has been made to the functional load (or FL) principle in establishing priorities for L2 pronunciation teaching, it remains an under-theorized and relatively under-utilized concept. This is despite the existence of empirical

Externí odkaz: https://doaj.org/article/32bd62d3bf1548fdbd5ce6cb3c567b87

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Akademický článek

Magnitude and Kinetics of T Cell and Antibody Responses During H1N1pdm09 Infection in Inbred Babraham Pigs and Outbred Pigs

Autor: Matthew Edmans, Adam McNee, Emily Porter, Eleni Vatzia, Basu Paudyal, Veronica Martini, Simon Gubbins, Ore Francis, Ross Harley, Amy Thomas, Rachel Burt, Sophie Morgan, Anna Fuller, Andrew Sewell, Bryan Charleston, Mick Bailey, Elma Tchilian

Publikováno v: Frontiers in Immunology, Vol 11 (2021)

We have used the pig, a large natural host animal for influenza with many physiological similarities to humans, to characterize αβ, γδ T cell and antibody (Ab) immune responses to the 2009 pandemic H1N1 virus infection. We evaluated the kinetic o

Externí odkaz: https://doaj.org/article/0992007ecdf24d4e9a275a2c3c219d65

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Exploratory investigation of a patient‐informed low‐dose psilocybin pulse regimen in the suppression of cluster headache: Results from a randomized, double‐blind, placebo‐controlled trial

Autor: Emmanuelle A. D. Schindler, R. Andrew Sewell, Christopher H. Gottschalk, Christina Luddy, L. Taylor Flynn, Yutong Zhu, Hayley Lindsey, Brian P. Pittman, Nicholas V. Cozzi, Deepak C. D'Souza

Publikováno v: Headache: The Journal of Head and Face Pain. 62:1383-1394

Using a patient-informed regimen, we conducted an exploratory randomized, double-blind, placebo-controlled study to systematically investigate the effects of psilocybin in cluster headache.Sustained reductions in cluster headache burden after limited

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ff59f9b6dafdf31bbf6520e6605f639
https://doi.org/10.1111/head.14420

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Figure S1 from Demethylation Therapy as a Targeted Treatment for Human Papillomavirus–Associated Head and Neck Cancer

Autor: Natalia Issaeva, Wendell G. Yarbrough, Saral Mehra, Benjamin Judson, Barbara Burtness, Aarti Bhatia, Hari A. Deshpande, Gary Bellinger, Cyril Gary, Andrew Sewell, Michael Hajek, Asel Biktasova

A. Cytokeratin levels in HPV+ and HPV- cells used in the study; human osteosarcoma cells U2OS were used as a negative control. B. TP53 mRNA levels in UMSCC47 cells expressing control, or two different p53 shRNAs. C. Cytokeratin levels in tumors from

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::190de4497e81eb21b747d7309cfe6624
https://doi.org/10.1158/1078-0432.22467017

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