Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Andrew Seeber"'
Autor:
Verena Hurst, Christian B. Gerhold, Cleo V. D. Tarashev, Kiran Challa, Andrew Seeber, Shota Yamazaki, Britta Knapp, Stephen B. Helliwell, Bernd Bodenmiller, Masahiko Harata, Kenji Shimada, Susan M. Gasser
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-22 (2024)
Abstract Loss of cytosolic actin filaments upon TORC2 inhibition triggers chromosome fragmentation in yeast, which results from altered base excision repair of Zeocin-induced lesions. To find the link between TORC2 kinase and this yeast chromosome sh
Externí odkaz:
https://doaj.org/article/c6eea7d7981e47d3bf6b2e622889e3f4
Publikováno v:
Cell Reports, Vol 18, Iss 5, Pp 1200-1214 (2017)
Chromatin moves with subdiffusive and spatially constrained dynamics within the cell nucleus. Here, we use single-locus tracking by time-lapse fluorescence microscopy to uncover information regarding the forces that influence chromatin movement follo
Externí odkaz:
https://doaj.org/article/78c65dd2255c43b4bbc593c2c27ac8ee
Autor:
Isabella Marcomini, Kenji Shimada, Neda Delgoshaie, Io Yamamoto, Andrew Seeber, Anais Cheblal, Chihiro Horigome, Ulrike Naumann, Susan M. Gasser
Publikováno v:
Cell Reports, Vol 24, Iss 10, Pp 2614-2628.e4 (2018)
Summary: Multiple pathways regulate the repair of double-strand breaks (DSBs) to suppress potentially dangerous ectopic recombination. Both sequence and chromatin context are thought to influence pathway choice between non-homologous end-joining (NHE
Externí odkaz:
https://doaj.org/article/6090c9e0c3a348d482c16f70271fa99c
Publikováno v:
High-Speed Biomedical Imaging and Spectroscopy VIII.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43ca8540900397d5797d755f9078e939
https://doi.org/10.1117/12.2651584
https://doi.org/10.1117/12.2651584
Autor:
Kristen M. Koenig, Dushan N. Wadduwage, Anders S. Hansen, Tadasu Nozaki, Ajay S. Labade, Andrew D. Stephens, Lingluo Chu, Jan-Hendrik Spille, Assaf Amitai, Sergey Ovchinnikov, Andrew Seeber, Haitham A. Shaban, Aditi Chakrabarti, Sirui Liu, Jason D. Buenrostro, Jun-Han Su, Andrews Akwasi Agbleke
Publikováno v:
PMC
Mol Cell
Mol Cell
© 2020 Elsevier Inc. Nucleosomes package genomic DNA into chromatin. By regulating DNA access for transcription, replication, DNA repair, and epigenetic modification, chromatin forms the nexus of most nuclear processes. In addition, dynamic organiza
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0d2db1f2e54c4cd47c7e37ae1744c92
https://doi.org/10.1016/j.molcel.2020.07.003
https://doi.org/10.1016/j.molcel.2020.07.003
Publikováno v:
Trends in Cell Biology. 30:144-156
The increased mobility of damaged DNA within the nucleus can promote genome stability and cell survival. New cell biology approaches have indicated that damaged DNA mobility exhibits random and directed movements during DNA repair. Here, we review re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33cbaf89b6459f5b35de84b866325ecc
https://doi.org/10.1016/j.tcb.2019.11.003
https://doi.org/10.1016/j.tcb.2019.11.003
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 35(7)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb2d80cf75ff4dbc6ad6bfb5aceca734
https://pubmed.ncbi.nlm.nih.gov/34143494
https://pubmed.ncbi.nlm.nih.gov/34143494
Autor:
Dimos Gaidatzis, Peter Askjaer, Véronique Kalck, Jan Padeken, Susan M. Gasser, Celia Muñoz-Jiménez, Andrew Seeber, Daphne S. Cabianca
Publikováno v:
Nature
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digital.CSIC. Repositorio Institucional del CSIC
instname
The execution of developmental programs of gene expression requires an accurate partitioning of the genome into subnuclear compartments, with active euchromatin enriched centrally and silent heterochromatin at the nuclear periphery1. The existence of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8b394dced6247b96e0f8a3c8ff9d3d5
https://doi.org/10.1038/s41586-019-1243-y
https://doi.org/10.1038/s41586-019-1243-y
Autor:
Andrew Seeber, Antonin Morillon, Susan M. Gasser, Ugo Szachnowski, Marie-Bénédicte Barrault, Romain Forey, Cécile Ducrot, Jérôme Poli, Armelle Lengronne, Antoine Barthe, Julie Soutourina, Oliver J. Rando, Jennifer A. Cobb, Michel Werner, Nils Krietenstein, Mireille Tittel-Elmer, Maxime Wery, Philippe Pasero, Magdalena Skrzypczak, Karine Dubrana, Krzysztof Ginalski, Maga Rowicka
Publikováno v:
Mol Cell
Molecular Cell
Molecular Cell, Elsevier, 2020, ⟨10.1016/j.molcel.2020.11.010⟩
Molecular Cell
Molecular Cell, Elsevier, 2020, ⟨10.1016/j.molcel.2020.11.010⟩
Mre11-Rad50-Xrs2 (MRX) is a highly conserved complex with key roles in various aspects of DNA repair. Here, we report a new function for MRX in limiting transcription in budding yeast. We show that MRX interacts physically and colocalizes on chromati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce9b78dc991ade7b7fd99baabfa3cd7d
https://europepmc.org/articles/PMC8112817/
https://europepmc.org/articles/PMC8112817/
Autor:
Kiran Challa, Saho Kitagawa, Christoph D. Schmid, Assaf Amitai, Michael H. Hauer, Jan Seebacher, Susan M. Gasser, Anais Cheblal, Kenji Shimada, Andrew Seeber, Vytautas Iesmantavicius
Publikováno v:
Molecular cell. 81(4)
Eukaryotic cells package their genomes around histone octamers. In response to DNA damage, checkpoint activation in yeast induces core histone degradation resulting in 20%-40% reduction in nucleosome occupancy. To gain insight into this process, we d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7ef7c3438ce54d7cc37fa559979feb5
https://pubmed.ncbi.nlm.nih.gov/33529595
https://pubmed.ncbi.nlm.nih.gov/33529595