Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Andrew Sandstrom"'
Autor:
Elaine P. Dopfer, Frederike A. Hartl, Hans-Heinrich Oberg, Gabrielle M. Siegers, O. Sascha Yousefi, Sylvia Kock, Gina J. Fiala, Beatriz Garcillán, Andrew Sandstrom, Balbino Alarcón, Jose R. Regueiro, Dieter Kabelitz, Erin J. Adams, Susana Minguet, Daniela Wesch, Paul Fisch, Wolfgang W.A. Schamel
Publikováno v:
Cell Reports, Vol 7, Iss 5, Pp 1704-1715 (2014)
Activation of the T cell receptor (TCR) by antigen is the key step in adaptive immunity. In the αβTCR, antigen induces a conformational change at the CD3 subunits (CD3 CC) that is absolutely required for αβTCR activation. Here, we demonstrate tha
Externí odkaz:
https://doaj.org/article/d96a71cd8e9c4d03be71b8194bfc3b6e
Publikováno v:
Inflammasome Biology ISBN: 9780323918022
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c19ee64800f2800902a1aaf0f5ee6d1a
https://doi.org/10.1016/b978-0-323-91802-2.00012-8
https://doi.org/10.1016/b978-0-323-91802-2.00012-8
Autor:
Antonio Abbate, Ivona Aksentijevich, Marcelo Pires Amaral, Magaiver Andrade-Silva, Diego Angosto-Bazarra, Luca Antonioli, Kübra Aral, Juan I. Aróstegui, Jillian Barlow, Laura Benvenuti, Nunzia Bernardini, Massimo Bertinaria, Monika Biasizzo, Karina Ramalho Bortoluci, Dave Boucher, Laura Migliari Branco, David Brough, Petr Broz, Clare E. Bryant, Mark Cahill, Matthew Campbell, Soo Jung Cho, Shelbi Christgen, Rebecca C. Coll, Isabelle Couillin, Brianna Cyr, Sarah Dalmon, Juan Pablo de Rivero Vaccari, Francesco Di Virgilio, Andrea Dorfleutner, Sarah L. Doyle, Vanessa D'Antongiovanni, Ariel E. Feldstein, Matteo Fornai, Carlos García-Palenciano, Simone Gastaldi, Matthias Geyer, François Ghiringhelli, Anna Lisa Giuliani, José Manuel González-Navajas, Iva Hafner-Bratkovič, Shaima'a Hamarsheh, Michael T. Heneka, Thomas Henry, Jun-ichi Hikima, Inga V. Hochheiser, Alexander Hogg, Alexander Hooftman, Christopher Hoyle, Yin Huang, Sarah Huot-Marchand, Laura Hurtado-Navarro, Sushmita Jha, Thirumala-Devi Kanneganti, Benedikt Kaufmann, Andrea D. Kim, Nataša Kopitar-Jerala, Jordana Kron, Silvia Lucena Lage, Beatriz Lozano-Ruiz, Elisabetta Marini, Billie Matchett, Adolfo G. Mauro, Eleonora Mezzaroma, Michael R. Milward, Ingrid Kazue Mizuno Watanabe, Natsuki Morimoto, Sandip Mukherjee, Mar Orzáez, Luke A.J. O'Neill, Pablo Pelegrín, Carolina Pellegrini, Anaïs Perrichet, Joanna Picó, Nicola Potere, Alexander Pronko, Kishore Aravind Ravichandran, Nicolas Riteau, Kim S. Robinson, Cédric Rébé, Fadi N. Salloum, Mónica Sancho, Andrew Sandstrom, Niels Olsen Saraiva Câmara, Florian I. Schmidt, Liang Shan, Eoin Silke, Paula M. Soriano-Teruel, Christian Stehlik, Heather Stout-Delgado, Arianne L. Theiss, Jenny P.-Y. Ting, Stefano Toldo, Elviche L. Tsakem, Rebecca E. Tweedell, Amalia Tzoumpa, K. Venuprasad, Rose Wellens, Robert Zeiser, Franklin L. Zhong, Alessia Zotta
Publikováno v:
Inflammasome Biology ISBN: 9780323918022
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1df40277879d3530be000cf63f0ec15f
https://doi.org/10.1016/b978-0-323-91802-2.01002-1
https://doi.org/10.1016/b978-0-323-91802-2.01002-1
Autor:
Andrew Sandstrom
Publikováno v:
Journal of Experimental Medicine. 220
In this issue of JEM, Jenster et al. (2022. J. Exp. Med. https://doi.org/10.1084/jem.20220837) investigate how UVB radiation promotes activation of the inflammatory immune sensor NLRP1, and in doing so uncover how NLRP1 recognizes a diverse range of
Publikováno v:
Curr Opin Immunol
Nucleotide-binding domain, leucine-rich repeat (NLR) proteins constitute a diverse class of innate immune sensors that detect pathogens or stress-associated stimuli in plants and animals. Some NLRs are activated upon direct binding to pathogen-derive
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Numerous cell death-controlling genes have been identified in fungi, especially in the context of conspecific nonself discrimination (allorecognition). However, our understanding of the molecular mechanisms by which these genes trigger p
Autor:
Lisa Goers, Russell E. Vance, Edward W. Mu, Patrick S. Mitchell, Andrew Sandstrom, Cammie F. Lesser
Publikováno v:
Science (New York, N.Y.), vol 364, iss 6435
Inflammasomes are multi-protein platforms that initiate innate immunity by recruitment and activation of Caspase-1. The NLRP1B inflammasome is activated upon direct cleavage by the anthrax lethal toxin protease. However, the mechanism by which cleava
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3b70d6171efe55aedc3f5cb2d9e6bbe
https://europepmc.org/articles/PMC6532986/
https://europepmc.org/articles/PMC6532986/
Autor:
Andrew Sandstrom, Russell E. Vance
Publikováno v:
Journal of Experimental Medicine, vol 215, iss 3
The Journal of Experimental Medicine
The Journal of Experimental Medicine
In this issue of JEM, Boucher et al. report isolation of active caspase-1 from macrophages after inflammasome activation. Surprisingly, they find that caspase-1 is quickly inactivated upon autoproteolytic processing.
In this issue of JEM, Bouche
In this issue of JEM, Bouche
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c79cc463135131f1e77cd5b2185155a0
https://escholarship.org/uc/item/9ps298wr
https://escholarship.org/uc/item/9ps298wr
Autor:
Andrew Sandstrom, Gabrielle McRae, Erin J. Adams, Stephen C. Meredith, Andrew J. Hawk, Louise Scharf
Publikováno v:
Journal of Biological Chemistry. 287:6035-6043
The molecular mechanisms by which γδ T cells recognize ligand remain a mystery. The non-classical MHC molecule T22 represents the best characterized ligand for murine γδ T cells, with a motif (W … EGYEL) present in the γδ T cell receptor comp
Autor:
John H Heithaus, Erica M. Duguid, Shahir S. Rizk, Anthony A. Kossiakoff, Andrew Sandstrom, Marcin Paduch
Publikováno v:
Nature structural & molecular biology
We describe a phage display methodology for engineering synthetic antigen binders (sABs) that recognize either the apo or the ligand-bound conformation of maltose-binding protein (MBP). sABs that preferentially recognize the maltose-bound form of MBP