Výsledky vyhledávání - "Andrew Samy AbdelMalak"

A study of the allosteric inhibition of HCV RNA-dependent RNA polymerase and implementing virtual screening for the selection of promising dual-site inhibitors with low resistance potential

Autor: Andrew Samy AbdelMalak, Fady N. Baselious, Nasser S.M. Ismail, Heba S.A. El-Zahabi, Peter Sabry, Fady Hanna

Publikováno v: Journal of Receptors and Signal Transduction. 37:341-354

Structure-based pharmacophores were generated and validated using the bioactive conformations of different co-crystallized enzyme-inhibitor complexes for allosteric palm-1 and thumb-2 inhibitors of NS5B. Two pharmacophore models were obtained, one fo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b8feb39cff3adc3fbb20930fc94ff1e
https://doi.org/10.1080/10799893.2016.1248293

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