Výsledky vyhledávání - "Andrew S. Pierson"

Phase I trial of low-dose oral Clofarabine in myelodysplastic syndromes patients who have failed frontline therapy

Autor: Venkatesh K. Rudrapatna, Kenneth M. Boucher, Kimberly A. Morley, Andrew S. Pierson, James P. Kushner, Paul J. Shami, Christian T. Shull

Publikováno v: Leukemia research. 39(8)

We investigated protracted low-dose oral Clofarabine for the treatment of myelodysplastic syndromes (MDS). Adults with an International Prognostic Scoring System (IPSS) score of INT-1 or higher who had failed first line therapy were eligible. INT-1 p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a019dc2fe605e6a5cc30616d50b6edb4
https://pubmed.ncbi.nlm.nih.gov/26038120

Zobrazit plný text záznamu

Abstract LB-178: Phase I trial of low-dose oral clofarabine in myelodysplastic syndromes patients who have failed frontline therapy

Autor: Paul J. Shami, Christian T. Shull, Kimberly Morley, Venkatesh K. Rudrapatna, Andrew S. Pierson, James P. Kushner

Publikováno v: Cancer Research. 73:LB-178

Introduction: The nucleoside analogue clofarabine, given orally at 20 - 40 mg/m2 daily for 5 consecutive days, achieved a response rate of 43% in patients with high-risk MDS (J Clin Oncol 28:2755-60,2010). Toxicity was better at lower doses, with sim

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2c8d53dc6348f2c7395783b006f4fb65
https://doi.org/10.1158/1538-7445.am2013-lb-178

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání