Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Andrew S. Flies"'
Autor:
Andrew S. Flies, Emily J. Flies, Nicholas M. Fountain-Jones, Ruth E. Musgrove, Rodrigo K. Hamede, Annie Philips, Matthew R. F. Perrott, Magdalena Dunowska
Publikováno v:
mBio, Vol 14, Iss 4 (2023)
ABSTRACT Wildlife is the source of many emerging infectious diseases. Several viruses from the order Nidovirales have recently emerged in wildlife, sometimes with severe consequences for endangered species. The order Nidovirales is currently classifi
Externí odkaz:
https://doaj.org/article/ee253fbf1d03434fb77cd32b0986578d
Autor:
Chrissie E. B. Ong, Yuanyuan Cheng, Hannah V. Siddle, A. Bruce Lyons, Gregory M. Woods, Andrew S. Flies
Publikováno v:
Open Biology, Vol 12, Iss 10 (2022)
MHC-I and MHC-II molecules are critical components of antigen presentation and T cell immunity to pathogens and cancer. The two monoclonal transmissible devil facial tumours (DFT1, DFT2) exploit MHC-I pathways to overcome immunological anti-tumour an
Externí odkaz:
https://doaj.org/article/9cf22af03f78459993435df2140aef2c
Publikováno v:
Frontiers in Immunology, Vol 9 (2019)
The Tasmanian devil facial tumor (DFT) disease has led to an 80% reduction in the wild Tasmanian devil (Sarcophilus harrisii) population since 1996. The limited genetic diversity of wild devils and the lack of MHC-I expression on DFT cells have been
Externí odkaz:
https://doaj.org/article/478231e664964cc8a0ef8b9ac16b931a
Autor:
Andrew S. Flies, Gregory M. Woods
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Externí odkaz:
https://doaj.org/article/600db5319c054b009965e5cb078d343e
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Immune checkpoint molecules function as a system of checks and balances that enhance or inhibit immune responses to infectious agents, foreign tissues, and cancerous cells. Immunotherapies that target immune checkpoint molecules, particularly the inh
Externí odkaz:
https://doaj.org/article/7977ac92dfbd49dca7806dba5934aee6
Autor:
Ruth Pye, Jocelyn Darby, Andrew S. Flies, Samantha Fox, Scott Carver, Jodie Elmer, Kate Swift, Carolyn Hogg, David Pemberton, Gregory Woods, A. Bruce Lyons
Publikováno v:
Wildlife Research. 48:701-712
Context Disease is increasingly becoming a driver of wildlife population declines and an extinction risk. Vaccines are one of the most successful health interventions in human history, but few have been tested for mitigating wildlife disease. The tra
Autor:
Grace G Russell, Chiara Palmieri, Jocelyn Darby, Gary P. Morris, Nicholas M. Fountain-Jones, Ruth J. Pye, Andrew S. Flies
The wild Tasmanian devil (Sarchophilus harrisii) population has suffered a devastating decline due to two clonal transmissible cancers. Devil facial tumor 1 (DFT1) was first observed in 1996, followed by a second genetically distinct transmissible tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::26bb792951ee1d34ecfce9496b406a76
https://doi.org/10.1101/2022.10.31.513798
https://doi.org/10.1101/2022.10.31.513798
Autor:
null Chrissie E. B. Ong, null Yuanyuan Cheng, null Hannah V. Siddle, null A. Bruce Lyons, null Gregory M. Woods, null Andrew S. Flies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c535b85b7e7737eb7d0000858144457
https://doi.org/10.1098/rsob.220208/v2/response1
https://doi.org/10.1098/rsob.220208/v2/response1
Autor:
Ahab N. Kayigwe, Jocelyn M. Darby, A. Bruce Lyons, Amanda L. Patchett, Leszek Lisowski, Guei-Sheung Liu, Andrew S. Flies
The devil facial tumour disease (DFTD) has led to a massive decline in the wild Tasmanian devil (Sarcophilus harrisii) population. The disease is caused by two independent devil facial tumours (DFT1 and DFT2). These transmissible cancers have a morta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ece75573dd4dff1485463740c1e2b17
https://doi.org/10.1101/2022.05.29.493930
https://doi.org/10.1101/2022.05.29.493930
Autor:
Sean Dempsey, Ruth J. Pye, Amy T. Gilbert, Nicholas M. Fountain-Jones, Jennifer M. Moffat, Sarah Benson-Amram, Timothy J. Smyser, Andrew S. Flies
Publikováno v:
Wildlife Research.
ContextDiseases are increasingly contributing to wildlife population declines. Tasmanian devil (Sarcophilus harrisii) populations have locally declined by 82% largely due to the morbidity and mortality associated with two independent transmissible de