Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Andrew S. Flies"'
Autor:
Andrew S. Flies, Emily J. Flies, Nicholas M. Fountain-Jones, Ruth E. Musgrove, Rodrigo K. Hamede, Annie Philips, Matthew R. F. Perrott, Magdalena Dunowska
Publikováno v:
mBio, Vol 14, Iss 4 (2023)
ABSTRACT Wildlife is the source of many emerging infectious diseases. Several viruses from the order Nidovirales have recently emerged in wildlife, sometimes with severe consequences for endangered species. The order Nidovirales is currently classifi
Externí odkaz:
https://doaj.org/article/ee253fbf1d03434fb77cd32b0986578d
Autor:
Chrissie E. B. Ong, Yuanyuan Cheng, Hannah V. Siddle, A. Bruce Lyons, Gregory M. Woods, Andrew S. Flies
Publikováno v:
Open Biology, Vol 12, Iss 10 (2022)
MHC-I and MHC-II molecules are critical components of antigen presentation and T cell immunity to pathogens and cancer. The two monoclonal transmissible devil facial tumours (DFT1, DFT2) exploit MHC-I pathways to overcome immunological anti-tumour an
Externí odkaz:
https://doaj.org/article/9cf22af03f78459993435df2140aef2c
Publikováno v:
Frontiers in Immunology, Vol 9 (2019)
The Tasmanian devil facial tumor (DFT) disease has led to an 80% reduction in the wild Tasmanian devil (Sarcophilus harrisii) population since 1996. The limited genetic diversity of wild devils and the lack of MHC-I expression on DFT cells have been
Externí odkaz:
https://doaj.org/article/478231e664964cc8a0ef8b9ac16b931a
Autor:
Andrew S. Flies, Gregory M. Woods
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Externí odkaz:
https://doaj.org/article/600db5319c054b009965e5cb078d343e
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Immune checkpoint molecules function as a system of checks and balances that enhance or inhibit immune responses to infectious agents, foreign tissues, and cancerous cells. Immunotherapies that target immune checkpoint molecules, particularly the inh
Externí odkaz:
https://doaj.org/article/7977ac92dfbd49dca7806dba5934aee6
Autor:
Grace G Russell, Chiara Palmieri, Jocelyn Darby, Gary P. Morris, Nicholas M. Fountain-Jones, Ruth J. Pye, Andrew S. Flies
The wild Tasmanian devil (Sarchophilus harrisii) population has suffered a devastating decline due to two clonal transmissible cancers. Devil facial tumor 1 (DFT1) was first observed in 1996, followed by a second genetically distinct transmissible tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::26bb792951ee1d34ecfce9496b406a76
https://doi.org/10.1101/2022.10.31.513798
https://doi.org/10.1101/2022.10.31.513798
Autor:
null Chrissie E. B. Ong, null Yuanyuan Cheng, null Hannah V. Siddle, null A. Bruce Lyons, null Gregory M. Woods, null Andrew S. Flies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c535b85b7e7737eb7d0000858144457
https://doi.org/10.1098/rsob.220208/v2/response1
https://doi.org/10.1098/rsob.220208/v2/response1
Autor:
Ahab N. Kayigwe, Jocelyn M. Darby, A. Bruce Lyons, Amanda L. Patchett, Leszek Lisowski, Guei-Sheung Liu, Andrew S. Flies
The devil facial tumour disease (DFTD) has led to a massive decline in the wild Tasmanian devil (Sarcophilus harrisii) population. The disease is caused by two independent devil facial tumours (DFT1 and DFT2). These transmissible cancers have a morta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ece75573dd4dff1485463740c1e2b17
https://doi.org/10.1101/2022.05.29.493930
https://doi.org/10.1101/2022.05.29.493930
Publikováno v:
Current Oncology Reports. 23
Immune checkpoint immunotherapies (ICI) are now approved for over 20 types of cancer and there are almost 6000 ongoing clinical trials investigating immuno-modulators as cancer therapies. This review investigated the effect of monoclonal antibody-bas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b34a1ac1cd7770a7f9c4150c73d9533
https://doi.org/10.1007/s11912-021-01095-x
https://doi.org/10.1007/s11912-021-01095-x
Autor:
Scott Carver, Luke Yates, Emily J. Flies, Nicholas M. Fountain-Jones, Michael A. Charleston, Andrew S. Flies
Some countries have been crippled by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic while others have emerged with few infections and fatalities; the factors underscoring this macro-epidemiological variation is one of the m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0bdcd13ed559203fb6c6e22596b0fcd
https://doi.org/10.1101/2021.07.12.21260394
https://doi.org/10.1101/2021.07.12.21260394