Zobrazeno 1 - 10
of 148
pro vyhledávání: '"Andrew S. Brohl"'
Autor:
Alison H. Kucharik, MD, Nina B. Curkovic, BS, Julio C. Chavez, MD, Kenneth Y. Tsai, MD, PhD, Andrew S. Brohl, MD, James M. Grichnik, MD, PhD
Publikováno v:
JAAD Case Reports, Vol 51, Iss , Pp 17-21 (2024)
Externí odkaz:
https://doaj.org/article/cf6009596b1044ac8f6e465a815ebcc4
Autor:
Goodwin G. Jinesh, Marian T. Smallin, Nino Mtchedlidze, Marco Napoli, John H. Lockhart, Elsa R. Flores, Andrew S. Brohl
Publikováno v:
iScience, Vol 27, Iss 11, Pp 111132- (2024)
Summary: The chromosome-19 miRNA cluster (C19MC) restricts viruses depending on the multinucleated state of placental trophoblasts. However, the relationship of C19MC to multinucleation is unknown. Here we show that C19MC is coexpressed in multiple c
Externí odkaz:
https://doaj.org/article/769c0b021f7f4c40ae301ee8a4976892
Autor:
Aasha I. Hoogland, Andrew S. Brohl, Brent J. Small, Lauren Michael, Evan Wuthrick, Zeynep Eroglu, Dukagjin Blakaj, Claire Verschraegen, Nikhil I. Khushalani, Heather S. L. Jim, Sungjune Kim
Publikováno v:
Cancer Medicine, Vol 13, Iss 14, Pp n/a-n/a (2024)
Abstract Background Merkel cell carcinoma is a rare skin cancer associated with poor survival. Based on a previous Phase II trial of adults with advanced Merkel cell carcinoma by Kim and colleagues (2022), there is now a strong rationale for combinat
Externí odkaz:
https://doaj.org/article/e3252975446043b48e54b4043aea4bb3
Autor:
Goodwin G. Jinesh, Marian T. Smallin, Nino Mtchedlidze, Isha Godwin, Marco Napoli, Nicole Hackel, Manali S. Phadke, Avani A. Deshpande, Xiaobo Li, John H. Lockhart, Jaden R. Baldwin, Suehelay Acevedo-Acevedo, Yifeng Gao, Michelle A. Reiser, Keiran S.M. Smalley, Elsa R. Flores, Andrew S. Brohl
Publikováno v:
Genes and Diseases, Vol 11, Iss 1, Pp 60-63 (2024)
Externí odkaz:
https://doaj.org/article/624c4cc1c1cb42cfb037970ea5e0a8af
Autor:
Darcy L. Welch, Brooke L. Fridley, Ling Cen, Jamie K. Teer, Sean J. Yoder, Fredrik Pettersson, Liping Xu, Chia-Ho Cheng, Yonghong Zhang, Mark G. Alexandrow, Shengyan Xiang, Mark Robertson-Tessi, Joel S. Brown, Jonathan Metts, Andrew S. Brohl, Damon R. Reed
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Osteosarcoma is the most common bone sarcoma in children and young adults. While universally delivered, chemotherapy only benefits roughly half of patients with localized disease. Increasingly, intratumoral heterogeneity is recognized as a s
Externí odkaz:
https://doaj.org/article/f7513fb0926f4a94b84dd06a5b81bbee
Autor:
Goodwin G. Jinesh, Andrew S. Brohl
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 7, Iss 1, Pp 1-17 (2022)
Abstract Metastasis is a pivotal event that accelerates the prognosis of cancer patients towards mortality. Therapies that aim to induce cell death in metastatic cells require a more detailed understanding of the metastasis for better mitigation. Tow
Externí odkaz:
https://doaj.org/article/cf9129dedb9d4c748cb2a8f0e9757431
Autor:
Todd C. Knepper, Robyn A. Panchaud, Elnara Muradova, Leah Cohen, James A. DeCaprio, Nikhil I. Khushalani, Kenneth Y. Tsai, Andrew S. Brohl
Publikováno v:
Cancer Medicine, Vol 10, Iss 17, Pp 5889-5896 (2021)
Abstract Background The use of targeted therapy remains a treatment consideration for some patients with advanced Merkel cell carcinoma (MCC). However, supportive data on the use of targeted therapy approaches are limited. Thus, we sought to evaluate
Externí odkaz:
https://doaj.org/article/03143699f2cc4cb1b346c3d03f6e54ed
Autor:
Goodwin G. Jinesh, Marco Napoli, Marian T. Smallin, Andrew Davis, Hayley D. Ackerman, Payal Raulji, Nicole Montey, Elsa R. Flores, Andrew S. Brohl
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract A subset of hepatocellular carcinoma (HCC) overexpresses the chromosome 19 miRNA cluster (C19MC) and is associated with an undifferentiated phenotype marked by overexpression of cancer testis antigens (CTAs) including anti-apoptotic melanoma
Externí odkaz:
https://doaj.org/article/f977964cb58a4ac9af6d2441471a3653
Autor:
Bradley H. Sipe, Sarah G. Običan, Evita Henderson-Jackson, Nicole D. Riddle, Rikesh Makanji, Ricardo J. Gonzalez, Andrew S. Brohl
Publikováno v:
Case Reports in Oncological Medicine, Vol 2021 (2021)
We report a case of a 25-year-old pregnant woman diagnosed with a large, unresectable retroperitoneal synovial sarcoma. Successful neoadjuvant treatment with doxorubicin plus ifosfamide prepartum and continuing postpartum resulted in significant dise
Externí odkaz:
https://doaj.org/article/cd8f9379527d4fb3b8c6124ee8b5f633
Publikováno v:
Diagnostic Pathology, Vol 13, Iss 1, Pp 1-4 (2018)
Abstract Background RAF family activating fusions have been described as a potentially targetable molecular finding in a subset of soft tissue sarcomas. To further expand upon the landscape of this genetic feature, we describe a novel MTAP-RAF1 activ
Externí odkaz:
https://doaj.org/article/922e9eb970904958a7173129ae8a707a