Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Andrew S. Barrow"'
Autor:
Emily R. R. Mackie, Andrew S. Barrow, Marie-Claire Giel, Mark D. Hulett, Anthony R. Gendall, Santosh Panjikar, Tatiana P. Soares da Costa
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-11 (2023)
Abstract Herbicide resistance represents one of the biggest threats to our natural environment and agricultural sector. Thus, new herbicides are urgently needed to tackle the rise in herbicide-resistant weeds. Here, we employed a novel strategy to re
Externí odkaz:
https://doaj.org/article/eceeb3445de3486eb8e9a93af8083536
Autor:
Christopher J. Smedley, Paul A. Stanley, Mohannad E. Qazzaz, Andrea E. Prota, Natacha Olieric, Hilary Collins, Harry Eastman, Andrew S. Barrow, Kuan-Hon Lim, Toh-Seok Kam, Brian J. Smith, Hendrika M. Duivenvoorden, Belinda S. Parker, Tracey D. Bradshaw, Michel O. Steinmetz, John E. Moses
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-7 (2018)
Abstract The jerantinine family of Aspidosperma indole alkaloids from Tabernaemontana corymbosa are potent microtubule-targeting agents with broad spectrum anticancer activity. The natural supply of these precious metabolites has been significantly d
Externí odkaz:
https://doaj.org/article/cd703e3a1db842d9bf536015c27b64dc
Autor:
Lucio Manzi, Andrew S. Barrow, Daniel Scott, Robert Layfield, Timothy G. Wright, John E. Moses, Neil J. Oldham
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
Mapping protein-ligand interactions is fundamental to advance the understanding of cellular processes and to develop drug discovery strategies. Here, the authors present a photo-activated probe that allows highly efficient labelling and identificatio
Externí odkaz:
https://doaj.org/article/e5438de36b074b1c86bc4b655e92a87c
Autor:
Emily RR Mackie, Andrew S Barrow, Rebecca M Christoff, Belinda M Abbott, Anthony R Gendall, Tatiana P Soares da Costa
Publikováno v:
eLife, Vol 11 (2022)
Herbicides with novel modes of action are urgently needed to safeguard global agricultural industries against the damaging effects of herbicide-resistant weeds. We recently developed the first herbicidal inhibitors of lysine biosynthesis, which provi
Externí odkaz:
https://doaj.org/article/cbc58527ee934f6ab656dd0d1580b3ac
Publikováno v:
IUBMB Life. 74:1232-1252
Although the prevalence of antibiotic resistance is increasing at an alarming rate, there are a dwindling number of effective antibiotics available. Thus, the development of novel antibacterial agents should be of utmost importance. Peptidoglycan bio
Publikováno v:
Chemical Communications. 57:6991-6994
The hydration of carbon–carbon triple bonds is an important and atom economic synthetic transformation. Herein, we report a mild and selective method for the catalytic Markovnikov hydration of (E)-aryl enynes to the corresponding enones, mediated t
Autor:
Andrew S. Barrow, Alessandra Ottonello, K. Barry Sharpless, Dennis W. Wolan, Gencheng Li, Yunfei Cheng, Marie-Claire Giel, Seiya Kitamura, John E. Moses, Christopher J. Smedley, Timothy L Gialelis
Publikováno v:
Angew Chem Int Ed Engl
Diversity Oriented Clicking (DOC) is a unified click-approach for the modular synthesis of lead-like structures through application of the wide family of click transformations. DOC evolved from the concept of achieving "diversity with ease", by combi
Autor:
Christopher J. Smedley, Gencheng Li, Andrew S. Barrow, Timothy L. Gialelis, Marie‐Claire Giel, Alessandra Ottonello, Yunfei Cheng, Seiya Kitamura, Dennis W. Wolan, K. Barry Sharpless, John E. Moses
Publikováno v:
Angewandte Chemie. 132:12560-12569
Autor:
Emily R. R. Mackie, Andrew S. Barrow, Marie-Claire Giel, Mark D. Hulett, Anthony R. Gendall, Santosh Panjikar, Tatiana P. Soares da Costa
Herbicide resistance represents one of the biggest threats to our natural environment and agricultural sector. Thus, new herbicides are urgently needed to tackle the rise in herbicideresistant weeds. Here, we employed a novel strategy to repurpose a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4142f50f399c8861c709e16a57bb8dd1
https://doi.org/10.1101/2022.02.20.481218
https://doi.org/10.1101/2022.02.20.481218