Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Andrew S Lowe"'
Autor:
Marcus N Leiwe, Aenea C Hendry, Andrew D Bard, Stephen J Eglen, Andrew S Lowe, Ian D Thompson
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0144846 (2016)
The mouse dorsal lateral geniculate nucleus (dLGN) is an intermediary between retina and primary visual cortex (V1). Recent investigations are beginning to reveal regional complexity in mouse dLGN. Using local injections of retrograde tracers into V1
Externí odkaz:
https://doaj.org/article/a1729da7c3f346fab30ede16c8034b7d
Autor:
Myrianni Constantinou, Silvia Marino, Sebastian Brandner, Tedani El-Hassan, James Innes, Natasha Aley, Ayad Eddaoudi, Raquel Fonseca, Joanne Lau, Andrew S. Lowe
Publikováno v:
Laboratory Investigation; a Journal of Technical Methods and Pathology
The phenotype of glioma-initiating cells (GIC) is modulated by cell-intrinsic and cell-extrinsic factors. Phenotypic heterogeneity and plasticity of GIC is an important limitation to therapeutic approaches targeting cancer stem cells. Plasticity also
Publikováno v:
Developmental Neurobiology. 75:557-568
Mapping anatomical and functional parameters of the zebrafish brain is moving apace. Research communities undertaking such studies are becoming ever larger and more diverse. The unique features, tools, and technologies associated with zebrafish are p
Autor:
Gema Vizcay-Barrena, Mark Rigby, Cian O'Donnell, Roland A. Fleck, Federico W. Grillo, Juan Burrone, Andrew S. Lowe, Alison S. Walker, Guilherme Neves, Rachel E. Jackson
Publikováno v:
Walker, A S, Neves, G, Grillo, F, Jackson, R E, Rigby, M, O'Donnell, C, Lowe, A S, Vizcay-Barrena, G, Fleck, R A & Burrone, J 2017, ' Distance-dependent gradient in NMDAR-driven spine calcium signals along tapering dendrites ', Proceedings of the National Academy of Sciences of the United States of America, vol. 114, no. 10, pp. 1986-1995 . https://doi.org/10.1073/pnas.1607462114
Walker, A S, Neves, G, Grillo, F, Jackson, R E, Rigby, M, O'Donnell, C, Lowe, A S, Vizcay-Barrena, G, Fleck, R A & Burrone, J 2017, ' Distance-dependent gradient in NMDAR-driven spine calcium signals along tapering dendrites ', Proceedings of the National Academy of Sciences of the United States of America, vol. 114, no. 10, pp. E1986-E1995 . https://doi.org/10.1073/pnas.1607462114
Walker, A S, Neves, G, Grillo, F, Jackson, R E, Rigby, M, O'Donnell, C, Lowe, A S, Vizcay-Barrena, G, Fleck, R A & Burrone, J 2017, ' Distance-dependent gradient in NMDAR-driven spine calcium signals along tapering dendrites ', Proceedings of the National Academy of Sciences of the United States of America, vol. 114, no. 10, pp. E1986-E1995 . https://doi.org/10.1073/pnas.1607462114
Neurons receive a multitude of synaptic inputs along their dendritic arbor, but how this highly heterogeneous population of synaptic compartments is spatially organized remains unclear. By measuring N-methyl-d-aspartic acid receptor (NMDAR)-driven ca
Autor:
Mark Rigby, Virgile Viasnoff, Juan Burrone, Andrew S. Lowe, Stephanie Hynes, Ivo Lieberam, Carolina Barcellos Machado, Victoria Gonzalez Sabater, Peter Harley, Danielle Stevenson, Perrine Pluchon
Publikováno v:
Advanced Biosystems
Advanced Biosystems, Wiley-VCH, 2019, pp.1800307. ⟨10.1002/adbi.201800307⟩
Barcellos Machado, C, Pluchon, P, Harley, P, Rigby, M, Gonzalez Sabater Budilov, V, Stevenson, D C, Hynes, S, Lowe, A, Burrone, J, Viasnoff, V & Lieberam, I 2019, ' In Vitro Modeling of Nerve–Muscle Connectivity in a Compartmentalized Tissue Culture Device ', Advanced Biosystems, vol. 3, no. 7, 1800307, pp. 1-14 . https://doi.org/10.1002/adbi.201800307
Advanced Biosystems, Wiley-VCH, 2019, pp.1800307. ⟨10.1002/adbi.201800307⟩
Barcellos Machado, C, Pluchon, P, Harley, P, Rigby, M, Gonzalez Sabater Budilov, V, Stevenson, D C, Hynes, S, Lowe, A, Burrone, J, Viasnoff, V & Lieberam, I 2019, ' In Vitro Modeling of Nerve–Muscle Connectivity in a Compartmentalized Tissue Culture Device ', Advanced Biosystems, vol. 3, no. 7, 1800307, pp. 1-14 . https://doi.org/10.1002/adbi.201800307
Motor neurons project axons from the hindbrain and spinal cord to muscle, where they induce myofibre contractions through neurotransmitter release at neuromuscular junctions. Studies of neuromuscular junction formation and homeostasis have been large
Publikováno v:
Hunter, P R, Lowe, A S, Thompson, I & Meyer, M P 2013, ' Emergent properties of the optic tectum revealed by population analysis of direction and orientation selectivity ', Journal of Neuroscience, vol. 33, no. 35, pp. 13940-13945 . https://doi.org/10.1523/JNEUROSCI.1493-13.2013
How local circuits within the brain process visual information has classically been addressed at the single neuron level. Such reductionist approaches, however, struggle to capture the full scope of functional properties associated with even "simple"
Publikováno v:
Lowe, A S, Nikolaou, N, Hunter, P R, Thompson, I D & Meyer, M P 2013, ' A Systems-Based Dissection of Retinal Inputs to the Zebrafish Tectum Reveals Different Rules for Different Functional Classes during Development ', Journal of Neuroscience, vol. 33, no. 35, pp. 13946-13956 . https://doi.org/10.1523/JNEUROSCI.1866-13.2013
We have examined the form, diversity, and organization of three functional classes of retinal inputs to the zebrafish optic tectum during development. Our systems-based approach was to analyze data from populations of retinal ganglion cells labeled w
Autor:
Panagiotis G. Kyrtatos, Stephen L. Hart, Michele J. Writer, Cameron W. McLeod, Gavin D. Kenny, John A. Pugh, Mark F. Lythgoe, Andrew S. Lowe, Edward White, Alison Bienemann, Steven S. Gill, Claudio Villegas-Llerena
Publikováno v:
Journal of Controlled Release
Gadolinium-labelled nanocomplexes offer prospects for the development of real-time, non-invasive imaging strategies to visualise the location of gene delivery by MRI. In this study, targeted nanoparticle formulations were prepared comprising a cation
Autor:
Thomas Steckler, Andrew M. Blamire, Marleen Verhoye, Sakthivel Sekar, J. Van Audekerke, Andrew S. Lowe, Greetje Vanhoutte, A. Van der Linden, Mohammed Shoaib
Publikováno v:
Psychopharmacology
Rationale One of the key targets of psychopharmacology research is to determine the potential sites of action of antidepressants in order to characterise their underlying mechanism of action. Objective Using blood oxygenation level-dependent (BOLD) p
Autor:
J. Van Audekerke, Andrew S. Lowe, Greetje Vanhoutte, Mohammed Shoaib, Thomas Steckler, A. Van der Linden, Sakthivel Sekar, Andrew M. Blamire, Marleen Verhoye
Publikováno v:
Psychopharmacology
Rationale The majority of psychoactive compounds, including antidepressants in clinical practice, were discovered largely by serendipity. The underlying neuropharmacological mechanisms of action of these compounds leading to resolution of depressive