Zobrazeno 1 - 10
of 137
pro vyhledávání: '"Andrew S Lee"'
Autor:
Ryan T Willett, N Sumru Bayin, Andrew S Lee, Anjana Krishnamurthy, Alexandre Wojcinski, Zhimin Lao, Daniel Stephen, Alberto Rosello-Diez, Katherine L Dauber-Decker, Grant D Orvis, Zhuhao Wu, Marc Tessier-Lavigne, Alexandra L Joyner
Publikováno v:
eLife, Vol 8 (2019)
For neural systems to function effectively, the numbers of each cell type must be proportioned properly during development. We found that conditional knockout of the mouse homeobox genes En1 and En2 in the excitatory cerebellar nuclei neurons (eCN) l
Externí odkaz:
https://doaj.org/article/dac5953036a24d41a919545b03161f3f
Publikováno v:
Advances in Ophthalmology Practice and Research, Vol 4, Iss 2, Pp 78-83 (2024)
Background: Online physician reviews increase transparency in health care, helping patients make informed decisions about their provider. Language processing techniques can quantify this data and allow providers to better understand patients' experie
Externí odkaz:
https://doaj.org/article/29ee73e8ff884912970e64f04953fea4
Autor:
Sin-Yu Chen, Yi-Ling Chen, Po-Chen Li, Tai-Shan Cheng, Yeh-Shiu Chu, Yi-Shan Shen, Hsin-Tung Chen, Wei-Ni Tsai, Chien-Ling Huang, Martin Sieber, Yuan-Chieh Yeh, Hsiao-Sheng Liu, Chi-Ling Chiang, Chih-Hung Chang, Andrew S. Lee, Yen-Han Tseng, Ly James Lee, Hsiu-Jung Liao, Hon-Kan Yip, Chi-Ying F. Huang
Publikováno v:
Journal of Biomedical Science, Vol 31, Iss 1, Pp 1-18 (2024)
Abstract Background Acute lung injury (ALI) is a life-threatening respiratory condition characterized by severe inflammation and lung tissue damage, frequently causing rapid respiratory failure and long-term complications. The microRNA let-7a-5p is i
Externí odkaz:
https://doaj.org/article/9dec6478d6d34d14974d0294891227b6
Autor:
Chi-Ling Chiang, Yifan Ma, Ya-Chin Hou, Junjie Pan, Sin-Yu Chen, Ming-Hsien Chien, Zhi-Xuan Zhang, Wei-Hsiang Hsu, Xinyu Wang, Jingjing Zhang, Hong Li, Lili Sun, Shannon Fallen, Inyoul Lee, Xing-Yu Chen, Yeh-Shiu Chu, Chi Zhang, Tai-Shan Cheng, Wen Jiang, Betty Y. S. Kim, Eduardo Reategui, Robert Lee, Yuan Yuan, Hsiao-Chun Liu, Kai Wang, Michael Hsiao, Chi-Ying F. Huang, Yan-Shen Shan, Andrew S. Lee, L. James Lee
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Pancreatic ductal adenocarcinoma (PDAC) tumours carry multiple gene mutations and respond poorly to treatments. There is currently an unmet need for drug carriers that can deliver multiple gene cargoes to target high solid tumour burden like
Externí odkaz:
https://doaj.org/article/af563ac9db814eeda373f30019d84562
Autor:
Shiyan Dong, Xuan Liu, Ye Bi, Yifan Wang, Abin Antony, DaeYong Lee, Kristin Huntoon, Seongdong Jeong, Yifan Ma, Xuefeng Li, Weiye Deng, Benjamin R. Schrank, Adam J. Grippin, JongHoon Ha, Minjeong Kang, Mengyu Chang, Yarong Zhao, Rongze Sun, Xiangshi Sun, Jie Yang, Jiayi Chen, Sarah K. Tang, L. James Lee, Andrew S. Lee, Lirong Teng, Shengnian Wang, Lesheng Teng, Betty Y. S. Kim, Zhaogang Yang, Wen Jiang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract The recent success of mRNA therapeutics against pathogenic infections has increased interest in their use for other human diseases including cancer. However, the precise delivery of the genetic cargo to cells and tissues of interest remains
Externí odkaz:
https://doaj.org/article/daa7ff6703414ccab6b6c9e5982dab8f
Publikováno v:
Channels, Vol 17, Iss 1 (2023)
ABSTRACTRecent human genetic studies have linked a variety of genetic variants in the CACNA1C and CACNA1D genes to neuropsychiatric and neurodevelopmental disorders. This is not surprising given the work from multiple laboratories using cell and anim
Externí odkaz:
https://doaj.org/article/8bc61feed9044c26881d1ca1bee22015
Autor:
Yifan Ma, Lili Sun, Jingjing Zhang, Chi‐ling Chiang, Junjie Pan, Xinyu Wang, Kwang Joo Kwak, Hong Li, Renliang Zhao, Xilal Y. Rima, Chi Zhang, Anan Zhang, Yutong Liu, Zirui He, Derek Hansford, Eduardo Reategui, Changsheng Liu, Andrew S. Lee, Yuan Yuan, Ly James Lee
Publikováno v:
Advanced Science, Vol 10, Iss 33, Pp n/a-n/a (2023)
Abstract Regenerative medicine in tissue engineering often relies on stem cells and specific growth factors at a supraphysiological dose. These approaches are costly and may cause severe side effects. Herein, therapeutic small extracellular vesicles
Externí odkaz:
https://doaj.org/article/be874cc7f6144b73a972bc525c73aa66
Autor:
Christina A. von Roemeling, Yifan Wang, Yaqing Qie, Hengfeng Yuan, Hai Zhao, Xiujie Liu, Zhaogang Yang, Mingming Yang, Weiye Deng, Katelyn A. Bruno, Charles K. Chan, Andrew S. Lee, Stephen S. Rosenfeld, Kyuson Yun, Aaron J. Johnson, Duane A. Mitchell, Wen Jiang, Betty Y. S. Kim
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Professional antigen presenting cells (APCs) are deterred from phagocytosing cancer cells that express CD47. Here, the authors show that in glioblastoma mouse models, temozolomide improves the phagocytosis effect of CD47 blockade in APCs and results
Externí odkaz:
https://doaj.org/article/eee195d796b64fada2ef877b68da61fb
Autor:
Grace Liang, Xianxi Huang, James Hirsch, Sanjeev Mehmi, Holly Fonda, Khin Chan, Ngan F. Huang, Oliver Aalami, Victor F. Froelicher, David P. Lee, Jonathan Myers, Andrew S. Lee, Patricia K. Nguyen
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Background: Although engaging in physical exercise has been shown to reduce the incidence of cardiovascular events, the molecular mechanisms by which exercise mediates these benefits remain unclear. Based on epidemiological evidence, reductions in tr
Externí odkaz:
https://doaj.org/article/4dca0fda971a4ca4ab843cf11fe2d3e3
Autor:
Liming Zhao, Andrew S. Lee, Koki Sasagawa, Jan Sokol, Yuting Wang, Ryan C. Ransom, Xin Zhao, Chao Ma, Holly M. Steininger, Lauren S. Koepke, Mimi R. Borrelli, Rachel E. Brewer, Lorene L.Y. Lee, Xianxi Huang, Thomas H. Ambrosi, Rahul Sinha, Malachia Y. Hoover, Jun Seita, Irving L. Weissman, Joseph C. Wu, Derrick C. Wan, Jun Xiao, Michael T. Longaker, Patricia K. Nguyen, Charles K.F. Chan
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology.
BACKGROUND: Peripheral vascular disease remains a leading cause of vascular morbidity and mortality worldwide despite advances in medical and surgical therapy. Besides traditional approaches, which can only restore blood flow to native arteries, an a