Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Andrew S Duncombe"'
Autor:
Lai Yee Orbell, Nouf Abutheraa, Andrew S Duncombe, Mary Frances McMullin, Ruben Mesa, Charlene M McShane, Glen James, Lesley A Anderson
Publikováno v:
eJHaem, Vol 4, Iss 4, Pp 1071-1080 (2023)
Abstract Alleviating symptom burden in patients with myeloproliferative neoplasms (MPNs) is imperative to achieving optimal management. Research remains to elucidate the relationship between the JAK2V617F (Janus kinase 2) mutation present in many MPN
Externí odkaz:
https://doaj.org/article/028c2022644a45cea8818fdbea71bab2
Autor:
Michael R Ardern-Jones, Hang T T Phan, Florina Borca, Matt Stammers, James Batchelor, Isabel C Reading, Sophie V Fletcher, Trevor Smith, Andrew S Duncombe
Publikováno v:
PLoS ONE, Vol 18, Iss 1, p e0280079 (2023)
BackgroundThe success of early dexamethasone therapy for hospitalised COVID-19 cases in treatment of Sars-CoV-2 infection may predominantly reflect its anti-inflammatory action against a hyperinflammation (HI) response. It is likely that there is sub
Externí odkaz:
https://doaj.org/article/c401526cf62b4996814b4e6ed5dc1641
Autor:
Dana M. Lewis, Nancy T.H. Colchester, David Allen, James A.R. Nicoll, Haider A. Katifi, Andrew S. Duncombe
Publikováno v:
Case Reports in Neurology, Vol 14, Iss 1, Pp 213-222 (2022)
It is well recognized that B-cell clonal disorders such as Waldenstrom’s macroglobulinaemia may affect the central nervous system by direct infiltration of malignant B cells (Bing-Neel syndrome). However, there is no recognition in the current lite
Externí odkaz:
https://doaj.org/article/23fcc1d11ab343938f301f662b201ec5
Autor:
Andrew S. Duncombe, Lesley A. Anderson, Glen James, Frank de Vocht, Lin Fritschi, Ruben Mesa, Mike Clarke, Mary Frances McMullin
Publikováno v:
HemaSphere, Vol 4, Iss 1, p e327 (2020)
Abstract. Despite the identification of acquired genetic mutations associated with Myeloproliferative Neoplasms (MPNs) there is a paucity of information relating to modifiable risk factors that may lead to these mutations. The MOSAICC Study was an ex
Externí odkaz:
https://doaj.org/article/404ef8beb7ec4f92baefcc2ec83f1d60
Autor:
Nancy T.H. Colchester, Haider A Katifi, Ashwin Pinto, David J. Allen, Robert N. Lown, Andrew S Duncombe, Tracy Burt
Publikováno v:
Haematologica
Autor:
Ying Teo, Michael R. Ardern-Jones, Hang Tt Phan, Andrew S Duncombe, Trevor Smith, Matt Stammers, Anastasia Koutalopoulou, James Batchelor, Florina Borca
Publikováno v:
Clin Med (Lond)
A significant proportion of COVID-19 patients show evidence of hyperinflammation (HI), of which secondary haemophagocytic lymphohistiocytosis (sHLH) is the most severe manifestation and diagnosed with HScore. Using a COVID-relevant modification of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72b25b9871e515d9a2e65176ac086c8a
https://eprints.soton.ac.uk/449727/
https://eprints.soton.ac.uk/449727/
Autor:
Sebastian Francis, Jaymathi Dhanapal, Lee Bond, Beth Psaila, Louise Wallis, Jennifer O'Sullivan, Anna L. Godfrey, Natalia Curto-Garcia, Andrew J. Innes, Richard Szydlo, Andrew McGregor, Laura Munro, Pratap Neelakantan, Siamak Arami, Rebecca Frewin, Adam J. Mead, Hayder Hussein, Frances Wadelin, James Russell, Steven Knapper, Peter Dyer, John Willan, Chun Huat Teh, Richard A. Salisbury, Mallika Sekhar, Manish Jain, Claire N. Harrison, Tim C. P. Somervaille, Shivani Joshi, C Cargo, Paolo Polzella, Mamta Garg, Andrew S Duncombe, Sarah Burns, Mary Frances McMullin, Dragana Milojkovic, Frederick Chen
Publikováno v:
Leukemia
Salisbury, R A, Curto-Garcia, N, O’Sullivan, J, Chen, F, Polzella, P, Godfrey, A L, Russell, J, Knapper, S, Willan, J, Frewin, R, Joshi, S, Arami, S, Burns, S, Teh, C H, Wadelin, F, Dhanapal, J, Neelakantan, P, Milojkovic, D, Psaila, B, Szydlo, R, Francis, S, Cargo, C, Jain, M, McGregor, A, Wallis, L, Duncombe, A, Hussein, H, Dyer, P, Munro, L, Bond, L, McMullin, M F, Somervaille, T C P, Garg, M, Sekhar, M, Harrison, C, Mead, A J & Innes, A J 2021, ' Results of a national UK physician reported survey of COVID-19 infection in patients with a myeloproliferative neoplasm ', Leukemia . https://doi.org/10.1038/s41375-021-01143-2
Salisbury, R A, Curto-Garcia, N, O’Sullivan, J, Chen, F, Polzella, P, Godfrey, A L, Russell, J, Knapper, S, Willan, J, Frewin, R, Joshi, S, Arami, S, Burns, S, Teh, C H, Wadelin, F, Dhanapal, J, Neelakantan, P, Milojkovic, D, Psaila, B, Szydlo, R, Francis, S, Cargo, C, Jain, M, McGregor, A, Wallis, L, Duncombe, A, Hussein, H, Dyer, P, Munro, L, Bond, L, McMullin, M F, Somervaille, T C P, Garg, M, Sekhar, M, Harrison, C, Mead, A J & Innes, A J 2021, ' Results of a national UK physician reported survey of COVID-19 infection in patients with a myeloproliferative neoplasm ', Leukemia . https://doi.org/10.1038/s41375-021-01143-2
Funder: Cancer Research UK (CRUK); doi: https://doi.org/10.13039/501100000289
Funder: DH | National Institute for Health Research (NIHR); doi: https://doi.org/10.13039/501100000272
Funder: DH | National Institute for Health Research (NIHR); doi: https://doi.org/10.13039/501100000272
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3cc49236661f92f59956750192b753b
Autor:
Trevor R.F. Smith, Isabel Reading, Michael R. Ardern-Jones, Hang T.T. Phan, Andrew S Duncombe, Sophie V. Fletcher, Matthew Stammers, Florina Borca, James Batchelor
BackgroundThe success of early dexamethasone therapy for hospitalised COVID-19 cases in treatment of Sars-CoV-2 infection may predominantly reflect its anti-inflammatory action against a hyperinflammation (HI) response. It is likely that there is sub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13c7e3d2f517116db79edfe5a53ebced
https://doi.org/10.1101/2021.06.16.21259011
https://doi.org/10.1101/2021.06.16.21259011
Autor:
Nancy TH Colchester, David Allen, Haider A Katifi, Tracy Burt, Robert N Lown, Ashwin A Pinto, Andrew S Duncombe
Publikováno v:
Journal of Neurology, Neurosurgery & Psychiatry. 93:A39.4-A40
There is ongoing debate as to the optimum treatment for IgM paraproteinaemic neuropathy, although there is accumulating evidence that rituximab benefits a proportion of patients. We present a case series of 18 patients with IgM paraproteinaemic neuro
Autor:
Philip George, Yvette Hoade, Sahra Ali, Simon Watt, Varun Mehra, Catherine Cargo, Fergus Jack, Paul Evans, Tiziana Fanelli, William J. Tapper, Alastair Whiteway, Gabriela Sciuccati, Iwo Pieniak, Jamie Cavenagh, Emma Das-Gupta, Andres Virchis, Nicole Naumann, Kavita Patel, Rowena Thomas-Dewing, Patrick Thornton, Kris Zegocki, Louise Wallis, Charlotte Grimley, Gonzalo Carreño-Tarragona, Peter Forsyth, Andreas Reiter, Nicholas C.P. Cross, Laura Munro, Kaljit Bhuller, Andrew S Duncombe, Andrew Chase, Barbara J. Bain, Mohamad Jawhar, Johannes Lübke, Ali Rismani, Sonja Burgstaller
Publikováno v:
Leukemia
Cross, N C P, Hoade, Y, Tapper, W J, Carreno-tarragona, G, Fanelli, T, Jawhar, M, Naumann, N, Pieniak, I, Lübke, J, Ali, S, Bhuller, K, Burgstaller, S, Cargo, C, Cavenagh, J, Duncombe, A S, Das-gupta, E, Evans, P, Forsyth, P, George, P, Grimley, C, Jack, F, Munro, L, Mehra, V, Patel, K, Rismani, A, Sciuccati, G, Thomas-dewing, R, Thornton, P, Virchis, A, Watt, S, Wallis, L, Whiteway, A, Zegocki, K, Bain, B J, Reiter, A & Chase, A 2018, ' Recurrent activating STAT5B N642H mutation in myeloid neoplasms with eosinophilia ', Leukemia . https://doi.org/10.1038/s41375-018-0342-3
Cross, N C P, Hoade, Y, Tapper, W J, Carreno-tarragona, G, Fanelli, T, Jawhar, M, Naumann, N, Pieniak, I, Lübke, J, Ali, S, Bhuller, K, Burgstaller, S, Cargo, C, Cavenagh, J, Duncombe, A S, Das-gupta, E, Evans, P, Forsyth, P, George, P, Grimley, C, Jack, F, Munro, L, Mehra, V, Patel, K, Rismani, A, Sciuccati, G, Thomas-dewing, R, Thornton, P, Virchis, A, Watt, S, Wallis, L, Whiteway, A, Zegocki, K, Bain, B J, Reiter, A & Chase, A 2018, ' Recurrent activating STAT5B N642H mutation in myeloid neoplasms with eosinophilia ', Leukemia . https://doi.org/10.1038/s41375-018-0342-3
Determining the underlying cause of persistent eosinophilia is important for effective clinical management but remains a diagnostic challenge in many cases. We identified STAT5B N642H, an established oncogenic mutation, in 27/1715 (1.6%) cases referr