Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Andrew S Brack"'
Publikováno v:
eLife, Vol 11 (2022)
The quiescent muscle stem cell (QSC) pool is heterogeneous and generally characterized by the presence and levels of intrinsic myogenic transcription factors. Whether extrinsic factors maintain the diversity of states across the QSC pool remains unkn
Externí odkaz:
https://doaj.org/article/6161cb6243494aedb6f5e9b29e658b79
Autor:
Emilie Barruet, Steven M Garcia, Katharine Striedinger, Jake Wu, Solomon Lee, Lauren Byrnes, Alvin Wong, Sun Xuefeng, Stanley Tamaki, Andrew S Brack, Jason H Pomerantz
Publikováno v:
eLife, Vol 9 (2020)
Although heterogeneity is recognized within the murine satellite cell pool, a comprehensive understanding of distinct subpopulations and their functional relevance in human satellite cells is lacking. We used a combination of single cell RNA sequenci
Externí odkaz:
https://doaj.org/article/5697e4aa60ac459c93de99abd3ea4723
Publikováno v:
PLoS Computational Biology, Vol 14, Iss 1, p e1005927 (2018)
Cell populations display heterogeneous and dynamic phenotypic states at multiple scales. Similar to molecular features commonly used to explore cell heterogeneity, cell behavior is a rich phenotypic space that may allow for identification of relevant
Externí odkaz:
https://doaj.org/article/7155a5a63bc740189f098f7284f912f6
Publikováno v:
eLife. 11
The quiescent muscle stem cell (QSC) pool is heterogeneous and generally characterized by the presence and levels of intrinsic myogenic transcription factors. Whether extrinsic factors maintain the diversity of states across the QSC pool remains unkn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::136c77f4c3c1edbddef947c1108018bd
https://pubmed.ncbi.nlm.nih.gov/36583937
https://pubmed.ncbi.nlm.nih.gov/36583937
SummaryThe quiescent muscle stem cell (QSC) pool is heterogeneous and generally characterized by the presence and levels of intrinsic myogenic transcription factors. Whether extrinsic factors maintain the diversity of states across the QSC pool remai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7337d6ba9dfddb978745ce63fe68b6fa
https://doi.org/10.1101/2020.10.20.347484
https://doi.org/10.1101/2020.10.20.347484
Autor:
Manmeet H. Raval, Pin-Chung Cheng, Nicholas Guardino, Sanjana Ahsan, Hao Zhou, Rajiv Lochan Tiwari, Lu Wang, Andrew Chareunsouk, Maxwell Ederer, Ara B. Hwang, Matt Ellenberger, Rob Pepin, Daniel Raftery, Daniel Promislow, Keyue Shen, Andrew S. Brack, Joseph T. Rodgers
Decline in the skeletal muscle stem cell (MuSC) function is a major contributor to age-associated impairments in muscle regeneration and function. The ability of MuSCs to activate (i.e. exit quiescence, enter the cell cycle, and divide) following inj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28d131a18ef953be98d7b655f1ee9d7b
Autor:
Alvin Wong, Andrew S. Brack, Emilie Barruet, Sun Xuefeng, Jake Wu, Jason H. Pomerantz, Solomon Lee, Lauren Byrnes, Katharine Striedinger, Stanley Tamaki, Steven M. Garcia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::033df26e83e77b9266826302ebe04a16
https://doi.org/10.7554/elife.51576.sa2
https://doi.org/10.7554/elife.51576.sa2
Publikováno v:
Development (Cambridge, England)
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Murine muscle stem cells (MuSCs) experience a transition from quiescence to activation that is required for regeneration, but it remains unknown if the trajectory and dynamics of activation change with age. Here, we use time-lapse imaging and single
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::241dfce7752a941e227f7976c63922bb
https://doi.org/10.1242/dev.183855
https://doi.org/10.1242/dev.183855