Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Andrew R. Lavik"'
Autor:
Andrew R Lavik, Osagie Ebekozien, Nudrat Noor, G Todd Alonso, Sarit Polsky, Scott M Blackman, Justin Chen, Sarah D Corathers, Carla Demeterco-Berggren, Mary Pat Gallagher, Margaret Greenfield, Ashley Garrity, Saketh Rompicherla, Robert Rapaport, Nana-Hawa Yayah Jones
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 107:1948-1955
Context The impact of the COVID-19 pandemic on individuals with type 1 diabetes remains poorly defined. Objective We examined United States trends in diabetic ketoacidosis (DKA) among individuals with type 1 diabetes (T1D) during the COVID-19 pandemi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1863d5c41d3393fc3e1952c5fccbe59a
https://doi.org/10.1210/clinem/dgac158
https://doi.org/10.1210/clinem/dgac158
Autor:
Andrew R, Lavik, Karen S, McColl, Fernanda O, Lemos, Martijn, Kerkhofs, Fei, Zhong, Michael, Harr, Daniela, Schlatzer, Kozo, Hamada, Katsuhiko, Mikoshiba, Francesco, Crea, Geert, Bultynck, Martin D, Bootman, Jan B, Parys, Clark W, Distelhorst
Publikováno v:
Biochimica et biophysica acta. Molecular cell research. 1869(4)
Pyruvate kinase isoform M2 (PKM2) is a rate-limiting glycolytic enzyme that is widely expressed in embryonic tissues. The expression of PKM2 declines in some tissues following embryogenesis, while other pyruvate kinase isozymes are upregulated. Howev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::81140f3336f24c93f24fb225396e384c
https://pubmed.ncbi.nlm.nih.gov/35026348
https://pubmed.ncbi.nlm.nih.gov/35026348
Autor:
Andrew R. Lavik, Karen S. McColl, Fernanda O. Lemos, Martijn Kerkhofs, Fei Zhong, Michael Harr, Daniela Schlatzer, Kozo Hamada, Katsuhiko Mikoshiba, Francesco Crea, Geert Bultynck, Martin D. Bootman, Jan B. Parys, Clark W. Distelhorst
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1869:119206
Pyruvate kinase isoform M2 (PKM2) is a rate-limiting glycolytic enzyme that is widely expressed in embryonic tissues. The expression of PKM2 declines in some tissues following embryogenesis, while other pyruvate kinase isozymes are upregulated. Howev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79297f172d870149cd2aa4c6e6492530
https://doi.org/10.1016/j.bbamcr.2021.119206
https://doi.org/10.1016/j.bbamcr.2021.119206
Autor:
Yuvraj Choudhary, Fei Zhong, John J. Pink, Ming-Jin Chang, Clark W. Distelhorst, Shigemi Matsuyama, Edward F Greenberg, Mitchell R. Smith, Frederic J. Reu, Andrew R. Lavik, Karen S. McColl
Publikováno v:
Oncotarget
Bcl-2 inhibits apoptosis by two distinct mechanisms but only one is targeted to treat Bcl-2-positive malignancies. In this mechanism, the BH1-3 domains of Bcl-2 form a hydrophobic pocket, binding and inhibiting pro-apoptotic proteins, including Bim.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b612996555438e1a3b31eab9ab9bf8e
https://doi.org/10.18632/oncotarget.4489
https://doi.org/10.18632/oncotarget.4489
Autor:
Jan B. Parys, Andrew R. Lavik, Fei Zhong, Michael J. Berridge, Ming-Jin Chang, Clark W. Distelhorst
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 111(3)
Significance The B-cell lymphoma-2 (Bcl-2) protein binds to the inositol 1,4,5-trisphosphate receptor (InsP 3 R), a ubiquitous intracellular Ca 2+ channel, thereby promoting cell survival by preventing excessive Ca 2+ elevation. We report here that t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75e952800d93df71e27cea43259db7a6
https://pubmed.ncbi.nlm.nih.gov/24395794
https://pubmed.ncbi.nlm.nih.gov/24395794
Autor:
Gil Peleg, Hanna M. Vermaat, William Tse, Zizhen Kang, Bryan L. Roth, Munna L. Agarwal, David N. Wald, Andrew R. Lavik, Kevin D. Bunting, Stanton L. Gerson, Shaolei Zang
Publikováno v:
Cancer research. 68(11)
As the pathophysiology of acute myelogenous leukemia (AML) involves a block of myeloid maturation, a desirable therapeutic strategy is to induce leukemic cell maturation to increase the efficacy and to avoid the side effects of traditional chemothera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a20ecc3ab8fdcfbb45a7221dab55bff3
https://pubmed.ncbi.nlm.nih.gov/18519698
https://pubmed.ncbi.nlm.nih.gov/18519698
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. (10):2205-2210
The anti-apoptotic protein Bcl-2 is a versatile regulator of cell survival. Its interactions with its own pro-apoptotic family members are widely recognized for their role in promoting the survival of cancer cells. These interactions are thus being t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1f3d80ba1357cf5689b83fcad849b5d