Zobrazeno 1 - 10
of 124
pro vyhledávání: '"Andrew R. Kompa"'
Publikováno v:
Toxins, Vol 14, Iss 2, p 100 (2022)
The uremic toxin indoxyl sulfate (IS), elevated in chronic kidney disease (CKD), is known to contribute towards progressive cardiovascular disease. IS activates the aryl hydrocarbon receptor (AhR) mediating oxidative stress and endothelial dysfunctio
Externí odkaz:
https://doaj.org/article/05a5457125e7444e904d4936ee6d329f
Autor:
Claire L. Curl, Vennetia R. Danes, James R. Bell, Antonia J. A. Raaijmakers, Wendy T. K. Ip, Chanchal Chandramouli, Tristan W. Harding, Enzo R. Porrello, Jeffrey R. Erickson, Fadi J. Charchar, Andrew R. Kompa, Amanda J. Edgley, David J. Crossman, Christian Soeller, Kimberley M. Mellor, Jonathan M. Kalman, Stephen B. Harrap, Lea M. D. Delbridge
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 11 (2018)
BackgroundAmong the growing numbers of patients with heart failure, up to one half have heart failure with preserved ejection fraction (HFpEF). The lack of effective treatments for HFpEF is a substantial and escalating unmet clinical need—and the l
Externí odkaz:
https://doaj.org/article/1d494628ead14a7dbee011a799b45a35
Autor:
Bing Hui Wang, Ella Zomer, Zanfina Ademi, Feby Savira, Danny Liew, Andrew R Kompa, Alice J. Owen
Publikováno v:
J Am Soc Nephrol
Background Kidney disease is associated with impaired work productivity. However, the collective effect of missed work days, reduced output at work, and early withdrawal from the workforce is rarely considered in health-economic evaluations. Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2d1395e0f8490b6f27822e8867a639c
https://doi.org/10.1681/asn.2020081148
https://doi.org/10.1681/asn.2020081148
Autor:
Bing Hui Wang, Amanda J. Edgley, Robert N. Willette, Feby Savira, Andrew R Kompa, Beat M. Jucker, Henry Krum, Darren J. Kelly
Publikováno v:
International Journal of Cardiology. 310:128-136
Background Cardiorenal syndrome (CRS) is a major health burden worldwide in need of novel therapies, as current treatments remain suboptimal. The present study assessed the therapeutic potential of apoptosis signal-regulating kinase 1 (ASK1) inhibiti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47784adab863ad880d146ae64e0d8122
https://doi.org/10.1016/j.ijcard.2020.04.015
https://doi.org/10.1016/j.ijcard.2020.04.015
Autor:
Haoyun Fang, Derek J. Hausenloy, Andrew Newcomb, Thomas Loudovaris, Lina Mariana, Raymond C.B. Wong, Priyadharshini Sivakumaran, Anne M. Kong, Shiang Y. Lim, Cameron Kos, Ritika Saxena, Bakhos A. Tannous, Andrew R Kompa, David W. Greening, Jarmon G Lees, Paul J. McMillan
Publikováno v:
Cardiovasc Res
Aims To establish pre-clinical proof of concept that sustained subcutaneous delivery of the secretome of human cardiac stem cells (CSCs) can be achieved in vivo to produce significant cardioreparative outcomes in the setting of myocardial infarction.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4fd42181e47448f99b8db5852f74394
Autor:
Dovile Anderson, David M. Kaye, Bernard L. Flynn, Danny Liew, Bing Hui Wang, Carmen V. Scullino, Ruth R Magaye, Darren J. Creek, Christopher M. Reid, Yue Hua, Andrew R Kompa, Li Huang, Xin Xiong, Stuart M. Pitson, Feby Savira
Non-dialysable protein-bound uremic toxins (PBUTs) contribute to the development of cardiovascular disease (CVD) in chronic kidney disease (CKD) and vice versa. PBUTs have been shown to alter sphingolipid imbalance. Dihydroceramide desaturase 1 (Des1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2841aa34de246c4a3de7fdcc183096f
https://hdl.handle.net/11541.2/148203
https://hdl.handle.net/11541.2/148203
Autor:
Feby Savira, Bing Hui Wang, Ella Zomer, Zanfina Ademi, Alice J. Owen, Andrew R Kompa, Danny Liew
Publikováno v:
European Heart Journal. 41
Background Coronary heart disease (CHD) is the highest individual disease burden in Australia and associated with productivity losses through unplanned absence from work, reduced output while at work and early labour force withdrawal. Approximately e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a1d867e26b4c9c8d9e79b02defcb1007
https://doi.org/10.1093/ehjci/ehaa946.1491
https://doi.org/10.1093/ehjci/ehaa946.1491
Autor:
Beat M. Jucker, Darren J. Kelly, Henry Krum, Robert N. Willette, Feby Savira, Bing Hui Wang, Andrew R Kompa, Amanda J. Edgley
Publikováno v:
International journal of cardiology. 323
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36d3a87f0efb2fee950d1d88c1e8d162
https://pubmed.ncbi.nlm.nih.gov/32712112
https://pubmed.ncbi.nlm.nih.gov/32712112
Autor:
Carmen V. Scullino, Stuart M. Pitson, Andrew R Kompa, Christopher A. Reid, David M. Kaye, Bing Hui Wang, Bernard L. Flynn, Feby Savira, Danny Liew, Darren J. Kelly, Li Huang, Xin Xiong, Ruth Magaye
Publikováno v:
Vascular pharmacology. 141
Protein-bound uremic toxins (PBUTs) have adverse effects on vascular function, which is imperative in the progression of cardiovascular and renal diseases. The role of sphingolipids in PBUT-mediated vasculo-endothelial pathophysiology is unclear. Thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b725b23e0fc362f234b595449550265e
https://pubmed.ncbi.nlm.nih.gov/34600152
https://pubmed.ncbi.nlm.nih.gov/34600152
Autor:
Andrew R Kompa, Bing Hui Wang, Zanfina Ademi, Feby Savira, Alice J. Owen, Ella Zomer, Danny Liew
Publikováno v:
European journal of preventive cardiology. 28(4)
Aims To determine the impact of preventing new (incident) cases of coronary heart disease (CHD) on years of life and productivity, using the novel measure ‘productivity-adjusted life year’ (PALY), over the next 10 years. Methods and results A dyn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::019f7f3c8b45713aa42537f370f7b50c
https://pubmed.ncbi.nlm.nih.gov/33623990
https://pubmed.ncbi.nlm.nih.gov/33623990